Genomic Location: sc0000001_pilon:332256...364163
NR annotation: XP_029212828.2, A disintegrin and metalloproteinase with thrombospondin motifs 2-like isoform X1 [Acropora millepora]
Species Acropora microphthalma · all data for this species · gene families
| CDS |
| amic_s0001.g29.t2 |
| Transcript |
| amic_s0001.g29.t2 |
| Protein |
| amic_s0001.g29.t2 |
| UniProt accession | Description |
|---|---|
| Q8C9W3 | A disintegrin and metalloproteinase with thrombospondin motifs 2 OS=Mus musculus OX=10090 GN=Adamts2 PE=1 SV=2 |
| P79331 | A disintegrin and metalloproteinase with thrombospondin motifs 2 OS=Bos taurus OX=9913 GN=ADAMTS2 PE=1 SV=1 |
| O95450 | A disintegrin and metalloproteinase with thrombospondin motifs 2 OS=Homo sapiens OX=9606 GN=ADAMTS2 PE=1 SV=2 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0002127 (this species only) · gene tree & orthology |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF19030 all species → | TSP1_ADAMTS | Thrombospondin type 1 domain | Domain | Interproscan |
| PF01562 all species → | Pep_M12B_propep | Reprolysin family propeptide | Family | Interproscan |
| PF00090 all species → | TSP_1 | Thrombospondin type 1 domain | Domain | Interproscan |
| PF05986 all species → | ADAMTS_spacer1 | ADAM-TS Spacer 1 | Domain | Interproscan |
| PF01847 all species → | VHL | VHL beta domain | Domain | Interproscan |
| PF00629 all species → | MAM | MAM domain, meprin/A5/mu | Domain | Interproscan |
| PF01421 all species → | Reprolysin | Reprolysin (M12B) family zinc metalloprotease | Domain | Interproscan |
| PF17771 all species → | ADAMTS_CR_2 | ADAMTS cysteine-rich domain 2 | Domain | Interproscan |
| PF19236 all species → | ADAMTS_CR_3 | ADAMTS cysteine-rich domain | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR000998 all species → | Domain | MAM domain | Interproscan |
| IPR013320 all species → | Homologous_superfamily | Concanavalin A-like lectin/glucanase domain superfamily | Interproscan |
| IPR050439 all species → | Family | ADAMTS and ADAMTS-like | Interproscan |
| IPR000884 all species → | Repeat | Thrombospondin type-1 (TSP1) repeat | Interproscan |
| IPR006586 all species → | Domain | ADAM, cysteine-rich domain | Interproscan |
| IPR036383 all species → | Homologous_superfamily | Thrombospondin type-1 (TSP1) repeat superfamily | Interproscan |
| IPR010909 all species → | Domain | PLAC | Interproscan |
| IPR037140 all species → | Homologous_superfamily | von Hippel-Lindau disease tumour suppressor, beta domain superfamily | Interproscan |
| IPR036208 all species → | Homologous_superfamily | VHL superfamily | Interproscan |
| IPR002870 all species → | Domain | Peptidase M12B, propeptide | Interproscan |
| IPR024079 all species → | Homologous_superfamily | Metallopeptidase, catalytic domain superfamily | Interproscan |
| IPR010294 all species → | Domain | ADAMTS/ADAMTS-like, Spacer 1 | Interproscan |
| IPR024053 all species → | Domain | von Hippel-Lindau disease tumour suppressor, beta domain | Interproscan |
| IPR001590 all species → | Domain | Peptidase M12B, ADAM/reprolysin | Interproscan |
| IPR041645 all species → | Domain | ADAMTS, cysteine-rich domain 2 | Interproscan |
| IPR045371 all species → | Domain | ADAMTS/ADAMTS-like, cysteine-rich domain 3 | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR13723 all species → | ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0016020 all species → | Cellular Component | membrane | Interproscan |
| GO:0004222 all species → | Molecular Function | metalloendopeptidase activity | Interproscan |
| GO:0006508 all species → | Biological Process | proteolysis | Interproscan |
| GO:0030198 all species → | Biological Process | extracellular matrix organization | Interproscan |
| GO:0031012 all species → | Cellular Component | extracellular matrix | Interproscan |
| GO:0008237 all species → | Molecular Function | metallopeptidase activity | Interproscan |
amic_s0001.g29.t2.Genes whose expression across the transcriptome samples of Acropora microphthalma tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.
No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.
Whether this gene can be visualised in the single-cell atlases of Acropora microphthalma, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.
No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.
Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.
No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.
Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.
| Analysis | What it does | Status | |
|---|---|---|---|
| Primer design | Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed. | template found | open → |
| BLAST | Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start. | template found | open → |
| Expression heatmap | Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it. | no expression matrix | – |
| Gene family / orthogroup | Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue. | open → | |
| Gene set analysis | Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it. | open → |