Gene detail

Detailed information of amic_s0011.g185.t2 in Acropora microphthalma

Genomic Location: sc0000011_pilon:2620707...2637121
NR annotation: XP_029204415.1, egl nine homolog 1-like isoform X4 [Acropora millepora]
Species abbreviation AMICR · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

Transcript

amic_s0011.g185.t2

TACTTTGTCAAATTCTTGCGATAGTAGTCAACTTAGGTTAAAATAGATACACCGGGTTGAAAGCTGTTAAAATTCTTTCGCCGAAGACATGTATGCCAAAGCACTATTTCAACGAAACAACATGGGAAAGACAAAAAACGTTTATCCAGGCTTAAAGTTAAATCTGCTTGGAAGGGAAGTTGATTATCGAAGAGATTATCTTATGAAGCTTTTTCTCCGTTCAAGGCTAGGAAATGACGGTTTGCTTCGCATGTCGAGCATAAATCGTACGGAAAACACTATGCGCTGCGATCTCTGCAATGAGAGAGCCTCTATCACATGTACGCGTTGTAAGATAGCGAGATATTGTTGTCCAGATCATCGAAAGGAAGATTGGAAATTTCACCAGAGAAGATGTCAAGGGCGAACTGAACAGCAATCTTCGGGTCAAGAAAGTTTCCCTAATGGTTCTCGAGTAAATGGCGAGATTGTGAGTACGGACTCGTTTCAAAATAGCGTTTCAGAGCAAGCAATTCGTGTTGTTGCTACACTTAGAAAACAAGGTTATTGTTATATCGATGACTTTCACGGTGAAACCACTGCCAAGAACATTCTAAACGAGGTTAAAAACTTACATCAAAGACAAAAGTTTACGGACGGCGAGTTGGTGTCTTCAAATGGCAACGGTAGTACACTGAACAAGAAAATTCGGGACGATAAGATAGCGTGGGTAGATGGAAGAGAAAAACATTGTGAAACAATTTCGTATCACATGAACGTCGTTAATTCATTGATAAGGAAATGCAACGAATTTGTTGAAGAATATGAAATTGAACATAGAACGAAGCAGGCCATGGTTGCTTGCTACCCAGGTCAAGGAACTGGGTACAAGAGGCACGTAGATAACCCAAGTCAAGATGGTCGCTGTATAACAACATTGTATTACCTCAACCCAGAATGGACGGAGGAGAAAGGAGGCATATTAAAACTATATCCAGGGGGTGGGGAGAAAGCTGTTCGTATTTTACCCATTCTGGACAGACTATTACTTTTTTGGTCAGATCGTAGAAATCCTCATGAAGTTGAACCATCCCATGATATCAGATATGCCATTACGCTGTGGTATTTTGACAAGAATGAAAGGGCCTTGTTTAAAGAAAAGCAAGAAGCCTTAAGGATGAAAGAACTGAACATGAAAATGAACCCCAAGGTGAATGGTCTCCAAGATGGAAATCGAAAAGACGAGAGCAGAAAGGCAGAATAGCATTGCAGATTTACAGATCATTATTAAGAACTTTGTATTCAATTTTCAAGAACGACAATGCAGCTTCCCAACAAGCAAGGCCTGATTGCATTATCAAGAGTGGAGTTACACAATCTCAGAGAGTTCATTTATGGTGCTAATGTTACCCACTCAGATTTACTATCTCTGCGACTAATTGTATAATAATCCTTTGCTGTGACTGTCTTTAAAGTCATAAAGCTTAATTCGTGTCCTGTTGCATTTGTATTCAATACAACTGCATAATGAGTTTTAGGCCACTAAAAGTCTAAGTCTTACAACTTTATCTTCTCTTGTTGGTTGGAGTTCTGGTCGTCAGAGAGACACCTAGTGATGACTAAACAACGTCACAGGAATATGTTTGGGTAGACCATGTCCAGCTTGTTGTGTTGATGGAATATTTCCATGCTCCATAGAGTTCATTTGGTTTAGCTACCTCTAAAAACAGAAATTAAGTGGCATCTTCTGTTGTTATCTTATACCCTTATATCCTTTTTTTTAAGTCTAGTGGAAGAACAAAAGAACCGAGTCAAGATTGTAGCCTTGACTGGTTTCTTTTGATCTTGCACGAAACAAGTGCGGCCTATCACACTAAAAACTATTGTACTATAAGCATTCTTCTCAGTGGCAGAACAGTGAAATTCTAACGAAATCAATACAACAAAATCGTAACATAAAGCTCTCCATTTTCTGGCACAACACAATTGTGGTTTGTATCATCAGCTTTTCTTCGTTGCTAGGAACGTGTTGTGGAGGAAAGCTATTTAATCCAGCCAATAAGGTGTTGCATAAAATGACAGCTTTATACTAGGTACTAATTCTTATTTCTATGACAAGAAGTTCTTTCTTAGAATTTCCCCAATTTTTCTGATTTTCCTTACTGTGTTGCTTAAGGGTGAAATCATTTCCATGCACTTCAACTCCAAAACGAATTTTCCATCCCTGATATTTTGCCTAATGCTATTGTCACCCTGATCATTATCAGCATCGATAACGCTTTTGTCTACTGGATAAATCTCTTTCCGCGCAGAAACATTTTGCGGTTCCACCCAACATAAACTCGAAGGCAGAAGTCATATGGCCCCAACCGAGCTGCTGAGAGAGAGGCAGGGGTCTGGCCCTAGAATGACATCACAAACTGCCTTCAAATCCAATTCTTCGTTACTCGCATGACGTCACAGTAGCCATTTTGATTAAAGAAAAGTATGGTGGCTGAGCACGGCTTTGAAAAGCAATAGCATGGAAACGCCAAGCACTTTGTTATGTAGACTCTTGCCAATTTTGTCAGTGTTTGAGCGGATTAGGCATCCCCTTTCAAACGGAAATCTGGAAGGTTAAAATGTCAAATATATGTTTTGGTGCAGCCAGAGCGAATTTTATTGAAAATAAAAGAAAAAGAAATGACAGTCGCGTTGTGAACTGGCGTTACGTACGTTAGTTATtagggagcttaagcacgcaacgtttttgagccacggacggcaaccggaagtgaacattttgcaggccaggacattggtctctcccagattttcaaagtaatcgtctctactagcgcaaagagacttaaaaatataaatgtggtagtgtgaa

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
P59722	Egl nine homolog 1 (Fragment) OS=Rattus norvegicus OX=10116 GN=Egln1 PE=2 SV=2
Q9GZT9	Egl nine homolog 1 OS=Homo sapiens OX=9606 GN=EGLN1 PE=1 SV=1
Q91YE3	Egl nine homolog 1 OS=Mus musculus OX=10090 GN=Egln1 PE=1 SV=2

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0001316 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF13640 all species →	2OG-FeII_Oxy_3	2OG-Fe(II) oxygenase superfamily	Domain	Interproscan
PF01753 all species →	zf-MYND	MYND finger	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR002893 all species →	Domain	Zinc finger, MYND-type	Interproscan
IPR044862 all species →	Domain	Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain	Interproscan
IPR005123 all species →	Domain	Oxoglutarate/iron-dependent dioxygenase	Interproscan
IPR006620 all species →	Domain	Prolyl 4-hydroxylase, alpha subunit	Interproscan
IPR051559 all species →	Family	Hypoxia-inducible factor prolyl hydroxylases	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR12907 all species →	EGL NINE HOMOLOG-RELATED	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0005506 all species →	Molecular Function	iron ion binding	Interproscan
GO:0016705 all species →	Molecular Function	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	Interproscan
GO:0031418 all species →	Molecular Function	L-ascorbic acid binding	Interproscan
GO:0008198 all species →	Molecular Function	ferrous iron binding	Interproscan
GO:0031543 all species →	Molecular Function	peptidyl-proline dioxygenase activity	Interproscan
GO:0071456 all species →	Biological Process	cellular response to hypoxia	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K09592	EGLN, HPH; hypoxia-inducible factor prolyl hydroxylase	EC:1.14.11.29	Renal cell carcinoma	ko05211	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.