Gene detail

Detailed information of amic_s0011.g91.t1 in Acropora microphthalma

Genomic Location: sc0000011_pilon:1073838...1079024
NR annotation: XP_015768874.1, PREDICTED: cathepsin L1-like isoform X4 [Acropora digitifera]
Species abbreviation AMICR · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

Transcript

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
A0A1S4F2V5	Cathepsin L-like peptidase OS=Aedes aegypti OX=7159 PE=1 SV=1
Q26636	Cathepsin L OS=Sarcophaga peregrina OX=7386 PE=1 SV=1
Q95029	Cathepsin L1 OS=Drosophila melanogaster OX=7227 GN=CtsL1 PE=2 SV=2

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0000608 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF08246 all species →	Inhibitor_I29	Cathepsin propeptide inhibitor domain (I29)	Domain	Interproscan
PF00112 all species →	Peptidase_C1	Papain family cysteine protease	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR000668 all species →	Domain	Peptidase C1A, papain C-terminal	Interproscan
IPR013128 all species →	Family	Peptidase C1A	Interproscan
IPR025661 all species →	Active_site	Cysteine peptidase, asparagine active site	Interproscan
IPR013201 all species →	Domain	Cathepsin propeptide inhibitor domain (I29)	Interproscan
IPR038765 all species →	Homologous_superfamily	Papain-like cysteine peptidase superfamily	Interproscan
IPR025660 all species →	Active_site	Cysteine peptidase, histidine active site	Interproscan
IPR000169 all species →	Active_site	Cysteine peptidase, cysteine active site	Interproscan
IPR039417 all species →	Domain	Papain-like cysteine endopeptidase	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR12411 all species →	CYSTEINE PROTEASE FAMILY C1-RELATED	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0006508 all species →	Biological Process	proteolysis	Interproscan
GO:0008234 all species →	Molecular Function	cysteine-type peptidase activity	Interproscan
GO:0004197 all species →	Molecular Function	cysteine-type endopeptidase activity	Interproscan
GO:0005615 all species →	Cellular Component	extracellular space	Interproscan
GO:0005764 all species →	Cellular Component	lysosome	Interproscan
GO:0006955 all species →	Biological Process	immune response	Interproscan
GO:0008656 all species →	Molecular Function	cysteine-type endopeptidase activator activity involved in apoptotic process	Interproscan
GO:0010952 all species →	Biological Process	positive regulation of peptidase activity	Interproscan
GO:0051603 all species →	Biological Process	proteolysis involved in protein catabolic process	Interproscan
GO:2001235 all species →	Biological Process	positive regulation of apoptotic signaling pathway	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K01365	CTSL; cathepsin L	EC:3.4.22.15	Glycosylphosphatidylinositol (GPI)-anchored proteins	ko00537	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.