Genomic Location: sc0000018_pilon:930479...935895
NR annotation: XP_029204599.1, DEP domain-containing mTOR-interacting protein-like isoform X3 [Acropora millepora]
Species Acropora microphthalma · all data for this species · gene families
| CDS |
| amic_s0018.g120.t1 |
| Transcript |
| amic_s0018.g120.t1 |
| Protein |
| amic_s0018.g120.t1 |
| UniProt accession | Description |
|---|---|
| Q8TB45 | DEP domain-containing mTOR-interacting protein OS=Homo sapiens OX=9606 GN=DEPTOR PE=1 SV=2 |
| Q570Y9 | DEP domain-containing mTOR-interacting protein OS=Mus musculus OX=10090 GN=Deptor PE=1 SV=2 |
| Q70Z35 | Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein OS=Homo sapiens OX=9606 GN=PREX2 PE=1 SV=1 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0004374 (this species only) · gene tree & orthology |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF00610 all species → | DEP | Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) | Domain | Interproscan |
| PF17820 all species → | PDZ_6 | PDZ domain | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR036388 all species → | Homologous_superfamily | Winged helix-like DNA-binding domain superfamily | Interproscan |
| IPR036034 all species → | Homologous_superfamily | PDZ superfamily | Interproscan |
| IPR000591 all species → | Domain | DEP domain | Interproscan |
| IPR036390 all species → | Homologous_superfamily | Winged helix DNA-binding domain superfamily | Interproscan |
| IPR001478 all species → | Domain | PDZ domain | Interproscan |
| IPR051832 all species → | Family | Regulators of mTOR signaling and Rac activation | Interproscan |
| IPR041489 all species → | Domain | PDZ domain 6 | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR22829 all species → | DEP DOMAIN PROTEIN | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0005515 all species → | Molecular Function | protein binding | Interproscan |
| GO:0035556 all species → | Biological Process | intracellular signal transduction | Interproscan |
| GO:0006469 all species → | Biological Process | negative regulation of protein kinase activity | Interproscan |
| GO:0023051 all species → | Biological Process | regulation of signaling | Interproscan |
| GO:1903940 all species → | Biological Process | negative regulation of TORC2 signaling | Interproscan |
| GO:1904262 all species → | Biological Process | negative regulation of TORC1 signaling | Interproscan |
amic_s0018.g120.t1.Genes whose expression across the transcriptome samples of Acropora microphthalma tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.
No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.
Whether this gene can be visualised in the single-cell atlases of Acropora microphthalma, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.
No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.
Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.
No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.
Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.
| Analysis | What it does | Status | |
|---|---|---|---|
| Primer design | Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed. | template found | open → |
| BLAST | Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start. | template found | open → |
| Expression heatmap | Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it. | no expression matrix | – |
| Gene family / orthogroup | Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue. | open → | |
| Gene set analysis | Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it. | open → |
