Genomic Location: sc0000116_pilon:798286...802524
NR annotation: XP_015761821.1, PREDICTED: rap guanine nucleotide exchange factor 1-like [Acropora digitifera]
Species abbreviation AMICR · all data for this species · gene families
| CDS |
| amic_s0116.g75.t1 |
| Transcript |
| amic_s0116.g75.t1 |
| Protein |
| amic_s0116.g75.t1 |
| UniProt accession | Description |
|---|---|
| Q13905 | Rap guanine nucleotide exchange factor 1 OS=Homo sapiens OX=9606 GN=RAPGEF1 PE=1 SV=3 |
| O77086 | Guanine nucleotide-releasing factor 2 OS=Drosophila melanogaster OX=7227 GN=C3G PE=1 SV=4 |
| Q8IS14 | Ras guanine nucleotide exchange factor J OS=Dictyostelium discoideum OX=44689 GN=gefJ PE=2 SV=1 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0008261 (this species only) |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF00618 all species → | RasGEF_N | RasGEF N-terminal motif | Domain | Interproscan |
| PF00617 all species → | RasGEF | RasGEF domain | Family | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR001895 all species → | Domain | Ras guanine-nucleotide exchange factors catalytic domain | Interproscan |
| IPR008937 all species → | Family | Ras-like guanine nucleotide exchange factor | Interproscan |
| IPR023578 all species → | Homologous_superfamily | Ras guanine nucleotide exchange factor domain superfamily | Interproscan |
| IPR000651 all species → | Domain | Ras-like guanine nucleotide exchange factor, N-terminal | Interproscan |
| IPR019804 all species → | Conserved_site | Ras guanine-nucleotide exchange factor, conserved site | Interproscan |
| IPR036964 all species → | Homologous_superfamily | Ras guanine-nucleotide exchange factor, catalytic domain superfamily | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR23113 all species → | GUANINE NUCLEOTIDE EXCHANGE FACTOR | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0005085 all species → | Molecular Function | guanyl-nucleotide exchange factor activity | Interproscan |
| GO:0007264 all species → | Biological Process | small GTPase-mediated signal transduction | Interproscan |
| GO:0005886 all species → | Cellular Component | plasma membrane | Interproscan |
| GO:0007265 all species → | Biological Process | Ras protein signal transduction | Interproscan |
| GO:0043547 all species → | Biological Process | positive regulation of GTPase activity | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K06277 | RAPGEF1, GRF2; Rap guanine nucleotide exchange factor 1 | - | Renal cell carcinoma | ko05211 | deepkoala |