Genomic Location: sc0000148_pilon:104977...113365
NR annotation: XP_029189738.2, protein disulfide-isomerase 2-like [Acropora millepora]
Species Acropora microphthalma · all data for this species · gene families
| CDS |
| amic_s0148.g12.t1 |
| Transcript |
| amic_s0148.g12.t1 |
| Protein |
| amic_s0148.g12.t1 |
| UniProt accession | Description |
|---|---|
| Q17770 | Protein disulfide-isomerase 2 OS=Caenorhabditis elegans OX=6239 GN=pdi-2 PE=1 SV=1 |
| Q5R5B6 | Protein disulfide-isomerase OS=Pongo abelii OX=9601 GN=P4HB PE=2 SV=1 |
| P07237 | Protein disulfide-isomerase OS=Homo sapiens OX=9606 GN=P4HB PE=1 SV=3 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0001207 (this species only) · gene tree & orthology |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF00085 all species → | Thioredoxin | Thioredoxin | Domain | Interproscan |
| PF13848 all species → | Thioredoxin_6 | Thioredoxin-like domain | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR013766 all species → | Domain | Thioredoxin domain | Interproscan |
| IPR036249 all species → | Homologous_superfamily | Thioredoxin-like superfamily | Interproscan |
| IPR017937 all species → | Conserved_site | Thioredoxin, conserved site | Interproscan |
| IPR005788 all species → | Domain | Protein disulfide-isomerase, thioredoxin-like domain | Interproscan |
| IPR005792 all species → | Family | Protein disulphide isomerase | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR18929 all species → | PROTEIN DISULFIDE ISOMERASE | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0003756 all species → | Molecular Function | protein disulfide isomerase activity | Interproscan |
| GO:0005783 all species → | Cellular Component | endoplasmic reticulum | Interproscan |
| GO:0006457 all species → | Biological Process | protein folding | Interproscan |
| GO:0034976 all species → | Biological Process | response to endoplasmic reticulum stress | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K09580 | PDIA1, P4HB; protein disulfide-isomerase A1 | EC:5.3.4.1 | Exosome | ko04147 | deepkoala |
Genes whose expression across the transcriptome samples of Acropora microphthalma tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.
No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.
Whether this gene can be visualised in the single-cell atlases of Acropora microphthalma, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.
No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.
Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.
No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.
Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.
| Analysis | What it does | Status | |
|---|---|---|---|
| Primer design | Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed. | template found | open → |
| BLAST | Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start. | template found | open → |
| Expression heatmap | Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it. | no expression matrix | – |
| Gene family / orthogroup | Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue. | open → | |
| Gene set analysis | Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it. | open → |