Gene detail

Detailed information of amic_s0168.g4.t1 in Acropora microphthalma

Genomic Location: sc0000168_pilon:22577...52585
NR annotation: XP_029213397.2, 2-aminomuconic semialdehyde dehydrogenase-like isoform X1 [Acropora millepora]
Species Acropora microphthalma · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

amic_s0168.g4.t1

ATGCCCGTTGCGAGCAGCTGCCAGTGCAAAGTTTCCCTAGCAGGACGAACAAGAACACAAACACAGCCACTCATGGACTTTATTGCGCAAATAAATCAGCTTTTCAGACGTGGAGAAATTTCGGACAACATTTATAATTTCATCAATGGCGAGTTCGTTCCTCCGGACAGCGGCGAATTTGGTGATACACACAATCCAAGCACAGGAGAAGCATTATGCAAATATCCACTTTCCAGTGTTTTCGATCTTCAAAAAGCAATTGAAGCAGCCAGTTCAGCATATCATATTTGGAAAAGGCAGTCTACGGTCGAAAGAGCCGAAGTGTTGAGCCTAATGGCCAATCTTTTCGAGAAGAGGTCAGAGCTTTTTCTTCGAGCTGAAATCTTGGATCAAGGACGAGCGATTCAGGGCGCGTTCAAAGACGACAATGATGTGGCGAGAGAAGTCCCTGTGATCAAACATTTCCTTGCACAGGCAATGGCAAGGACGGAATCTTCGACGAAGACGAGAGATTCTATCAGTTACTCAACCCGTTATCCATTGGGTGTGGTCGGAATAATCACCTCGTGGGCTTCTCCTCTGCGCTCTGTTTTGTGGCATGCGATCCCAGCACTGGCTTGTGGGAACACTGTTATAATTAAACCGTCGTGTTTGGCGCCGCTTGAGGTTCACCTACTCGCTAAAACTTTCAGTGATGCAGGATTACCGAAAGGTGTGGTCAATGTTGTTTATGGTAAAGGTGATGTTGTGGGCAAAGCTCTAAGTGCATCTTCTGTTGTAAAAGCTCTGGCATTTGTTGGAAATGAAAGAACAGCCTCCACTATATTGAGAGAATGTCAACTTCTTGTTACAAAAAAATTTTCATTCAGCTTGGGAAACTGTCATCCAATGATTATCTGCTATGACGCTGATCTCGACGAAGCGCTTCCCATCGCCATTAAAGGGAGttttctACAAAACGAGGGACAAAACGTTCATTCTATCAATCGCATTTTCGTTCAAGCATCCCTCCTCGAAACGTTCACCGACAGATTTATCAGAGTTGTACAGAGATTGAAGATTGGCAGCCCCCATGAAAGTAGCATACAAGTTGGTCCCTTAATAAGCAATGAACATAGACAAAAGATCATTGCGATTATTCAAGGTGCAGTAAATGATGGTGCAGAGATTTTATGTGGAGGAAAAATTCCCAAATTTGACAACAAATTGGATAGAGGATACTTTTTGGAGCCTACAGTTCTTGGTGGTTTTCAGAGTTCCATCGTCAACTCGATTAACTCGTTGGAGGTGCAAGGACCAGTGGTCAGATTGATACCATTTAACAGTATCAACGACGCGATAGATGGGGCCAATGCGACGTTGTATGGACTCTCTGCTTCAGTCTGGTGCAAGGATATCAGTTTAGCTCATACCATTGCAGATCGGTTAAATGTGGGTTCTGTGTGGATTAACAGCTGGTTACCCAACAACCCCAGCATGCCGTACGAGGGATGGAAGAGCAGTGGATTGGGGCGAACAGGAGGTGCCTACTCAATGGACTTTTACACCGAAATTAAAACTGTACACGCATACAGACAGAGTATTTATGGAAGAAAGTACGTATGGATTCTTCCTGGTTGGTACAGTGAAAACTGGTGGGAAAATTCAGGCGACAGTCCATGCACCGTACACCAAATAATGGAAGCGGCTGGAAACTACCTAGCGACCAGGCCTCTTCAGCTTGGTACATCCACGACGTCAACGATTGCTGGGAAGACTGTAACTGAGCTTCATAACGAACTAGATGACATCATCCGTAGCCATGCTTACCCGGTTAATGCATTCTCTTCTTTCGCTTATGATGCAATATGGAGTATTGCACTTACTCTAGACCAGGCTTCTTACATCCTCGATTCTCAAAATAAACAATTGTCAAACTTTACGTATGGAGACAATGAAACTGCCATCCTTTTTAGAGATATACTGCGAAATTTGTCATTTTACGGCATGTCGGGTCTTGTAAAATTTGATGAACACGGCGACAGAGAGACCTCAATAGAAATACTACAACTACAAGGCGATGCGAGAGTTGTTGTTAGCCTTTACAACAAATCAAAAACCGATTTGGATGGTTCACTTATGAAGTGGGATGGAAAGCTTCCAAAAGATGGTGTAATCATAAAAACCAAGGCAAATGAAGATTCCGTGGCGTACACAGTGACAATAATCTGTCTTTCTATTGGCGGGATAGTGGTTTCATTCCTTTGCTTGGCCGTGAATATAGCTTTCAGGAAACACAGAGTTATCAAGATGTCGTCTCCGCATTTCAACAACATAACCGCCGTTGGTGGTTTCATCTGTTATCTCTACGTTATTTTGGGCACAGTCAACCATTCAAGAACCTATTTTGGTGAATCTCATAATGTTTGTACGATAAGGGCGTACCTCATTGTGATAGGTTTTACATTAGTGTTTGGAGGGATGTTTGCCAAAACCTGGCGAGTGTACAAGATATTTACCAATAGACGTTTGAAGAGAGAAATAGGTGGGCTGAGTACAGTACAGTTAATGCTGGGAATATTTTGCATATTAGTTTTCGATATTGTGGTACTTGTCAGCTGGAATTTAATCGATCCAATGCAATTGAGGACTGTTGAAATCTCGGTGAACACAAATCAGGAAGACATAGAAATCCACACAACCACCCAGCAATGTGTGTCGAATTATTACTCCTCTTGGATCATTGGTTTGATTCTCTTCAAAGGAGCTCTTCTCCTCTTTGGCGTTTTCCTTGCCTGGGAAACTAGAAATGTTCATTACGCTGAACTCAACGATTCCAGAAACATCGGTGTGGCAGTTTATAACATTTTACTTTTTTCTGGAGTGTCCATCACTGCAGAGTTTGTTTTAAGTGACTTAATGGCCAAACGAATATTCAATAATTCTGTGATTTATTTGTGTGCAACTATGGTGTTGGGACTGGTTTTCATCCCAAAGATCTCTCGCCTTGCGCGCAGAACAAAAGTTCAGCCGGATGAGGGCCAACAGCAAAATAAAACCCAAATTTCAACTTCTCAAAGGGAGGCAGACTCTCAGGCTTCAAGAGAATGA

Transcript

amic_s0168.g4.t1

CAGTCTGCAGTTCGTGTTTTGCAATTCAAAACGCTTAATTTATGCCCGTTGCGAGCAGCTGCCAGTGCAAAGTTTCCCTAGCAGGACGAACAAGAACACAAACACAGCCACTCATGGACTTTATTGCGCAAATAAATCAGCTTTTCAGACGTGGAGAAATTTCGGACAACATTTATAATTTCATCAATGGCGAGTTCGTTCCTCCGGACAGCGGCGAATTTGGTGATACACACAATCCAAGCACAGGAGAAGCATTATGCAAATATCCACTTTCCAGTGTTTTCGATCTTCAAAAAGCAATTGAAGCAGCCAGTTCAGCATATCATATTTGGAAAAGGCAGTCTACGGTCGAAAGAGCCGAAGTGTTGAGCCTAATGGCCAATCTTTTCGAGAAGAGGTCAGAGCTTTTTCTTCGAGCTGAAATCTTGGATCAAGGACGAGCGATTCAGGGCGCGTTCAAAGACGACAATGATGTGGCGAGAGAAGTCCCTGTGATCAAACATTTCCTTGCACAGGCAATGGCAAGGACGGAATCTTCGACGAAGACGAGAGATTCTATCAGTTACTCAACCCGTTATCCATTGGGTGTGGTCGGAATAATCACCTCGTGGGCTTCTCCTCTGCGCTCTGTTTTGTGGCATGCGATCCCAGCACTGGCTTGTGGGAACACTGTTATAATTAAACCGTCGTGTTTGGCGCCGCTTGAGGTTCACCTACTCGCTAAAACTTTCAGTGATGCAGGATTACCGAAAGGTGTGGTCAATGTTGTTTATGGTAAAGGTGATGTTGTGGGCAAAGCTCTAAGTGCATCTTCTGTTGTAAAAGCTCTGGCATTTGTTGGAAATGAAAGAACAGCCTCCACTATATTGAGAGAATGTCAACTTCTTGTTACAAAAAAATTTTCATTCAGCTTGGGAAACTGTCATCCAATGATTATCTGCTATGACGCTGATCTCGACGAAGCGCTTCCCATCGCCATTAAAGGGAGttttctACAAAACGAGGGACAAAACGTTCATTCTATCAATCGCATTTTCGTTCAAGCATCCCTCCTCGAAACGTTCACCGACAGATTTATCAGAGTTGTACAGAGATTGAAGATTGGCAGCCCCCATGAAAGTAGCATACAAGTTGGTCCCTTAATAAGCAATGAACATAGACAAAAGATCATTGCGATTATTCAAGGTGCAGTAAATGATGGTGCAGAGATTTTATGTGGAGGAAAAATTCCCAAATTTGACAACAAATTGGATAGAGGATACTTTTTGGAGCCTACAGTTCTTGGTGGTTTTCAGAGTTCCATCGTCAACTCGATTAACTCGTTGGAGGTGCAAGGACCAGTGGTCAGATTGATACCATTTAACAGTATCAACGACGCGATAGATGGGGCCAATGCGACGTTGTATGGACTCTCTGCTTCAGTCTGGTGCAAGGATATCAGTTTAGCTCATACCATTGCAGATCGGTTAAATGTGGGTTCTGTGTGGATTAACAGCTGGTTACCCAACAACCCCAGCATGCCGTACGAGGGATGGAAGAGCAGTGGATTGGGGCGAACAGGAGGTGCCTACTCAATGGACTTTTACACCGAAATTAAAACTGTACACGCATACAGACAGAGTATTTATGGAAGAAAGTACGTATGGATTCTTCCTGGTTGGTACAGTGAAAACTGGTGGGAAAATTCAGGCGACAGTCCATGCACCGTACACCAAATAATGGAAGCGGCTGGAAACTACCTAGCGACCAGGCCTCTTCAGCTTGGTACATCCACGACGTCAACGATTGCTGGGAAGACTGTAACTGAGCTTCATAACGAACTAGATGACATCATCCGTAGCCATGCTTACCCGGTTAATGCATTCTCTTCTTTCGCTTATGATGCAATATGGAGTATTGCACTTACTCTAGACCAGGCTTCTTACATCCTCGATTCTCAAAATAAACAATTGTCAAACTTTACGTATGGAGACAATGAAACTGCCATCCTTTTTAGAGATATACTGCGAAATTTGTCATTTTACGGCATGTCGGGTCTTGTAAAATTTGATGAACACGGCGACAGAGAGACCTCAATAGAAATACTACAACTACAAGGCGATGCGAGAGTTGTTGTTAGCCTTTACAACAAATCAAAAACCGATTTGGATGGTTCACTTATGAAGTGGGATGGAAAGCTTCCAAAAGATGGTGTAATCATAAAAACCAAGGCAAATGAAGATTCCGTGGCGTACACAGTGACAATAATCTGTCTTTCTATTGGCGGGATAGTGGTTTCATTCCTTTGCTTGGCCGTGAATATAGCTTTCAGGAAACACAGAGTTATCAAGATGTCGTCTCCGCATTTCAACAACATAACCGCCGTTGGTGGTTTCATCTGTTATCTCTACGTTATTTTGGGCACAGTCAACCATTCAAGAACCTATTTTGGTGAATCTCATAATGTTTGTACGATAAGGGCGTACCTCATTGTGATAGGTTTTACATTAGTGTTTGGAGGGATGTTTGCCAAAACCTGGCGAGTGTACAAGATATTTACCAATAGACGTTTGAAGAGAGAAATAGGTGGGCTGAGTACAGTACAGTTAATGCTGGGAATATTTTGCATATTAGTTTTCGATATTGTGGTACTTGTCAGCTGGAATTTAATCGATCCAATGCAATTGAGGACTGTTGAAATCTCGGTGAACACAAATCAGGAAGACATAGAAATCCACACAACCACCCAGCAATGTGTGTCGAATTATTACTCCTCTTGGATCATTGGTTTGATTCTCTTCAAAGGAGCTCTTCTCCTCTTTGGCGTTTTCCTTGCCTGGGAAACTAGAAATGTTCATTACGCTGAACTCAACGATTCCAGAAACATCGGTGTGGCAGTTTATAACATTTTACTTTTTTCTGGAGTGTCCATCACTGCAGAGTTTGTTTTAAGTGACTTAATGGCCAAACGAATATTCAATAATTCTGTGATTTATTTGTGTGCAACTATGGTGTTGGGACTGGTTTTCATCCCAAAGATCTCTCGCCTTGCGCGCAGAACAAAAGTTCAGCCGGATGAGGGCCAACAGCAAAATAAAACCCAAATTTCAACTTCTCAAAGGGAGGCAGACTCTCAGGCTTCAAGAGAATGATGAGTTCTATGCGCAAATCAGTTATAAACGATAAAATCAAGA

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q9H2A2	2-aminomuconic semialdehyde dehydrogenase OS=Homo sapiens OX=9606 GN=ALDH8A1 PE=1 SV=1
Q8BH00	2-aminomuconic semialdehyde dehydrogenase OS=Mus musculus OX=10090 GN=Aldh8a1 PE=1 SV=1
Q66I21	2-aminomuconic semialdehyde dehydrogenase OS=Danio rerio OX=7955 GN=aldh8a1 PE=2 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0000413 (this species only) · gene tree & orthology

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF00171 all species →	Aldedh	Aldehyde dehydrogenase family	Family	Interproscan
PF01094 all species →	ANF_receptor	Receptor family ligand binding region	Family	Interproscan
PF00003 all species →	7tm_3	7 transmembrane sweet-taste receptor of 3 GCPR	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR016162 all species →	Homologous_superfamily	Aldehyde dehydrogenase, N-terminal	Interproscan
IPR016163 all species →	Homologous_superfamily	Aldehyde dehydrogenase, C-terminal	Interproscan
IPR002455 all species →	Family	GPCR family 3, GABA-B receptor	Interproscan
IPR016161 all species →	Homologous_superfamily	Aldehyde/histidinol dehydrogenase	Interproscan
IPR015590 all species →	Domain	Aldehyde dehydrogenase domain	Interproscan
IPR017978 all species →	Domain	GPCR family 3, C-terminal	Interproscan
IPR001828 all species →	Domain	Receptor, ligand binding region	Interproscan
IPR028082 all species →	Homologous_superfamily	Periplasmic binding protein-like I	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR10519 all species →	GABA-B RECEPTOR	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0016491 all species →	Molecular Function	oxidoreductase activity	Interproscan
GO:0016620 all species →	Molecular Function	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	Interproscan
GO:0004888 all species →	Molecular Function	transmembrane signaling receptor activity	Interproscan
GO:0004965 all species →	Molecular Function	G protein-coupled GABA receptor activity	Interproscan
GO:0007186 all species →	Biological Process	G protein-coupled receptor signaling pathway	Interproscan
GO:0007214 all species →	Biological Process	gamma-aminobutyric acid signaling pathway	Interproscan
GO:0016020 all species →	Cellular Component	membrane	Interproscan
GO:0038039 all species →	Cellular Component	G protein-coupled receptor heterodimeric complex	Interproscan
GO:0004930 all species →	Molecular Function	G protein-coupled receptor activity	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

No KEGG orthology assignment for amic_s0168.g4.t1.

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Co-expression network

Genes whose expression across the transcriptome samples of Acropora microphthalma tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Acropora microphthalma, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

Analysis	What it does	Status
Primer design	Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.	template found	open →
BLAST	Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.	template found	open →
Expression heatmap	Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.	no expression matrix	–
Gene family / orthogroup	Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.		open →
Gene set analysis	Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.		open →