Genomic Location: sc0000007_pilon:741955...764946
NR annotation: XP_029196361.2, insulin-degrading enzyme-like [Acropora millepora]
Species Acropora muricata · all data for this species · gene families
| CDS |
| amur_s0007.g50.t2 |
| Transcript |
| amur_s0007.g50.t2 |
| Protein |
| amur_s0007.g50.t2 |
| UniProt accession | Description |
|---|---|
| P14735 | Insulin-degrading enzyme OS=Homo sapiens OX=9606 GN=IDE PE=1 SV=4 |
| P35559 | Insulin-degrading enzyme OS=Rattus norvegicus OX=10116 GN=Ide PE=1 SV=1 |
| Q24K02 | Insulin-degrading enzyme OS=Bos taurus OX=9913 GN=IDE PE=2 SV=1 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0001147 (this species only) · gene tree & orthology |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF05193 all species → | Peptidase_M16_C | Peptidase M16 inactive domain | Domain | Interproscan |
| PF00675 all species → | Peptidase_M16 | Insulinase (Peptidase family M16) | Family | Interproscan |
| PF16187 all species → | Peptidase_M16_M | Middle or third domain of peptidase_M16 | Family | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR011249 all species → | Homologous_superfamily | Metalloenzyme, LuxS/M16 peptidase-like | Interproscan |
| IPR007863 all species → | Domain | Peptidase M16, C-terminal | Interproscan |
| IPR001431 all species → | Binding_site | Peptidase M16, zinc-binding site | Interproscan |
| IPR011765 all species → | Domain | Peptidase M16, N-terminal | Interproscan |
| IPR032632 all species → | Domain | Peptidase M16, middle/third domain | Interproscan |
| IPR050626 all species → | Family | Peptidase M16 | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR43690 all species → | NARDILYSIN | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0046872 all species → | Molecular Function | metal ion binding | Interproscan |
| GO:0004222 all species → | Molecular Function | metalloendopeptidase activity | Interproscan |
| GO:0006508 all species → | Biological Process | proteolysis | Interproscan |
| GO:0005739 all species → | Cellular Component | mitochondrion | Interproscan |
| GO:0005829 all species → | Cellular Component | cytosol | Interproscan |
| GO:0043171 all species → | Biological Process | peptide catabolic process | Interproscan |
| GO:0051603 all species → | Biological Process | proteolysis involved in protein catabolic process | Interproscan |
amur_s0007.g50.t2.Transcript abundance of amur_s0007.g50.t2 across 82 RNA-seq samples of Acropora muricata. This gene has no row in the species' RNA-seq expression matrix, so every value below is shown as zero — the matrix simply does not cover this transcript. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.
| Condition | Samples | TPM > 0 | Mean TPM | Max TPM | Mean, relative to max |
|---|---|---|---|---|---|
| Polyps | 79 | 0 | 0.00 | 0.00 | |
| Severed branch | 3 | 0 | 0.00 | 0.00 |
| SRA run | Condition | Tissue | Developmental stage | Treatment | Study | TPM |
|---|---|---|---|---|---|---|
| SRR12710849 | Polyps | Polyps | OA 2 day3 | not recorded | SRP199550 | 0.00 |
| SRR12710850 | Polyps | Polyps | OA 2 day3 | not recorded | SRP199550 | 0.00 |
| SRR12710851 | Polyps | Polyps | OA 2 day3 | not recorded | SRP199550 | 0.00 |
| SRR12710859 | Polyps | Polyps | OA 2 day9 | not recorded | SRP199550 | 0.00 |
| SRR12710860 | Polyps | Polyps | OA 2 day9 | not recorded | SRP199550 | 0.00 |
| SRR12710861 | Polyps | Polyps | OA 2 day9 | not recorded | SRP199550 | 0.00 |
| SRR12786899 | Polyps | Polyps | OA 2 day0 | not recorded | SRP199550 | 0.00 |
| SRR12786900 | Polyps | Polyps | OA 2 day0 | not recorded | SRP199550 | 0.00 |
| SRR12786901 | Polyps | Polyps | OA 2 day0 | not recorded | SRP199550 | 0.00 |
| SRR12807382 | Polyps | Polyps | OA2 day0 | not recorded | SRP199550 | 0.00 |
| SRR12904784 | Polyps | Polyps | not recorded | not recorded | SRP199550 | 0.00 |
| SRR12904785 | Polyps | Polyps | not recorded | not recorded | SRP199550 | 0.00 |
| SRR12904786 | Polyps | Polyps | not recorded | not recorded | SRP199550 | 0.00 |
| SRR12927881 | Polyps | Polyps | E2 day0 | not recorded | SRP199550 | 0.00 |
| SRR12959191 | Polyps | polyps | E2 day21 | not recorded | SRP199550 | 0.00 |
| SRR12959192 | Polyps | Polyps | E2 day21 | not recorded | SRP199550 | 0.00 |
| SRR12959193 | Polyps | Polyps | E2 day21 | not recorded | SRP199550 | 0.00 |
| SRR12959195 | Polyps | Polyps | E2 day0 | not recorded | SRP199550 | 0.00 |
| SRR12959204 | Polyps | Polyps | E2 day15 | not recorded | SRP199550 | 0.00 |
| SRR12959205 | Polyps | Polyps | E2 day15 | not recorded | SRP199550 | 0.00 |
| SRR12959206 | Polyps | Polyps | E2 day0 | not recorded | SRP199550 | 0.00 |
| SRR12959207 | Polyps | Polyps | E2 day15 | not recorded | SRP199550 | 0.00 |
| SRR12959217 | Polyps | Polyps | E2 day0 | not recorded | SRP199550 | 0.00 |
| SRR12959218 | Polyps | Polyps | E2 day9 | not recorded | SRP199550 | 0.00 |
| SRR12959219 | Polyps | Polyps | E2 day9 | not recorded | SRP199550 | 0.00 |
| SRR12959220 | Polyps | Polyps | E2 day9 | not recorded | SRP199550 | 0.00 |
| SRR12959231 | Polyps | Polyps | E2 day3 | not recorded | SRP199550 | 0.00 |
| SRR12959232 | Polyps | Polyps | E2 day3 | not recorded | SRP199550 | 0.00 |
| SRR12959233 | Polyps | Polyps | E2 day3 | not recorded | SRP199550 | 0.00 |
| SRR27868158 | Polyps | Polyps | regeneration day6 | not recorded | SRP199550 | 0.00 |
| SRR27868159 | Polyps | Polyps | regeneration day6 | not recorded | SRP199550 | 0.00 |
| SRR27868160 | Polyps | Polyps | regeneration day6 | not recorded | SRP199550 | 0.00 |
| SRR27868165 | Polyps | Polyps | regeneration day3 | not recorded | SRP199550 | 0.00 |
| SRR27868174 | Polyps | Polyps | regeneration day39 | not recorded | SRP199550 | 0.00 |
| SRR27868175 | Polyps | Polyps | regeneration day39 | not recorded | SRP199550 | 0.00 |
| SRR27868176 | Polyps | Polyps | regeneration day3 | not recorded | SRP199550 | 0.00 |
| SRR27868177 | Polyps | Polyps | regeneration day39 | not recorded | SRP199550 | 0.00 |
| SRR27868178 | Polyps | Polyps | regeneration day36 | not recorded | SRP199550 | 0.00 |
| SRR27868179 | Polyps | Polyps | regeneration day36 | not recorded | SRP199550 | 0.00 |
| SRR27868180 | Polyps | Polyps | regeneration day36 | not recorded | SRP199550 | 0.00 |
| SRR27868181 | Polyps | Polyps | regeneration day33 | not recorded | SRP199550 | 0.00 |
| SRR27868182 | Polyps | Polyps | regeneration day33 | not recorded | SRP199550 | 0.00 |
| SRR27868183 | Polyps | Polyps | regeneration day33 | not recorded | SRP199550 | 0.00 |
| SRR27868184 | Polyps | Polyps | regeneration day30 | not recorded | SRP199550 | 0.00 |
| SRR27868185 | Polyps | Polyps | regeneration day30 | not recorded | SRP199550 | 0.00 |
| SRR27868186 | Polyps | Polyps | regeneration day30 | not recorded | SRP199550 | 0.00 |
| SRR27868187 | Polyps | Polyps | regeneration day3 | not recorded | SRP199550 | 0.00 |
| SRR27868188 | Polyps | Polyps | regeneration day27 | not recorded | SRP199550 | 0.00 |
| SRR27868189 | Polyps | Polyps | regeneration day27 | not recorded | SRP199550 | 0.00 |
| SRR27868190 | Polyps | Polyps | regeneration day27 | not recorded | SRP199550 | 0.00 |
| SRR27868191 | Polyps | Polyps | regeneration day24 | not recorded | SRP199550 | 0.00 |
| SRR27868192 | Polyps | Polyps | regeneration day24 | not recorded | SRP199550 | 0.00 |
| SRR27868193 | Polyps | Polyps | regeneration day24 | not recorded | SRP199550 | 0.00 |
| SRR27868194 | Polyps | Polyps | regeneration day21 | not recorded | SRP199550 | 0.00 |
| SRR27868195 | Polyps | Polyps | regeneration day21 | not recorded | SRP199550 | 0.00 |
| SRR27868196 | Polyps | Polyps | regeneration day21 | not recorded | SRP199550 | 0.00 |
| SRR27868197 | Polyps | Polyps | regeneration day18 | not recorded | SRP199550 | 0.00 |
| SRR27868198 | Polyps | Polyps | regeneration day0 | not recorded | SRP199550 | 0.00 |
| SRR27868199 | Polyps | Polyps | regeneration day18 | not recorded | SRP199550 | 0.00 |
| SRR27868200 | Polyps | Polyps | regeneration day18 | not recorded | SRP199550 | 0.00 |
| SRR27868201 | Polyps | Polyps | regeneration day15 | not recorded | SRP199550 | 0.00 |
| SRR27868202 | Polyps | Polyps | regeneration day15 | not recorded | SRP199550 | 0.00 |
| SRR27868203 | Polyps | Polyps | regeneration day15 | not recorded | SRP199550 | 0.00 |
| SRR27868204 | Polyps | Polyps | regeneration day12 | not recorded | SRP199550 | 0.00 |
| SRR27868205 | Polyps | Polyps | regeneration day12 | not recorded | SRP199550 | 0.00 |
| SRR27868206 | Polyps | Polyps | regeneration day12 | not recorded | SRP199550 | 0.00 |
| SRR27868207 | Polyps | Polyps | regeneration day9 | not recorded | SRP199550 | 0.00 |
| SRR27868208 | Polyps | Polyps | regeneration day9 | not recorded | SRP199550 | 0.00 |
| SRR27868209 | Polyps | Polyps | regeneration day0 | not recorded | SRP199550 | 0.00 |
| SRR27868210 | Polyps | Polyps | regeneration day0 | not recorded | SRP199550 | 0.00 |
| SRR27940222 | Polyps | Polyps | not recorded | not recorded | SRP199550 | 0.00 |
| SRR27940224 | Polyps | Polyps | not recorded | not recorded | SRP199550 | 0.00 |
| SRR27940225 | Polyps | Polyps | not recorded | not recorded | SRP199550 | 0.00 |
| SRR27940226 | Polyps | Polyps | not recorded | not recorded | SRP199550 | 0.00 |
| SRR27940227 | Polyps | Polyps | not recorded | not recorded | SRP199550 | 0.00 |
| SRR27940228 | Polyps | Polyps | not recorded | not recorded | SRP199550 | 0.00 |
| SRR27940229 | Polyps | Polyps | not recorded | not recorded | SRP199550 | 0.00 |
| SRR9613488 | Polyps | Polyps | not recorded | not recorded | SRP199550 | 0.00 |
| SRR9613516 | Polyps | Polyps | not recorded | not recorded | SRP199550 | 0.00 |
| SRR12995717 | Severed branch | Severed branch | regeneration day0 | not recorded | SRP199550 | 0.00 |
| SRR12996627 | Severed branch | Severed branch | regeneration day0 | not recorded | SRP199550 | 0.00 |
| SRR12996628 | Severed branch | Severed branch | regeneration High gene expression | not recorded | SRP199550 | 0.00 |
Source: CnidoSite RNA-seq expression matrices (AMURI_TPM,
StringTie quantification over 82 runs), joined to SRA sample
metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped
by the descriptor carried in the expression matrix itself.
Genes whose expression across the transcriptome samples of Acropora muricata tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.
| Direction | Partners | Most correlated partner | PCC |
|---|---|---|---|
| Positively correlated | 0 | not in this network | - |
| Negatively correlated | 0 | not in this network | - |
This gene has no edge at all in the Acropora muricata network, in either direction — it is not one of the genes the network was built from (the network covers genes with enough expression variation across the transcriptome samples). The counts above are a property of the network, not a failed lookup.
Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list.
Whether this gene can be visualised in the single-cell atlases of Acropora muricata, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.
| Dataset | Tissue / stage | Cells | Cell types | This gene | Marker of |
|---|---|---|---|---|---|
| AMURI_regen | Polyps · regeneration | 8,721 | 28 | unmapped | – |
A gene is in viewer when the dataset ships a per-cell expression vector for it; marker only means it is in the dataset’s ranked marker table but no vector was exported, so the atlas cannot draw it; not in this dataset means the dataset’s own gene-ID table does not list it, so no expression claim can be made for that dataset. unmapped is deliberately weaker still: the dataset has no gene-ID table on CnidoSite yet, so nothing is claimed in either direction. Where markers are listed, the numbers are log2 fold change and the percentage of cells of that type in which the gene was detected.
Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.
No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.
Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.
| Analysis | What it does | Status | |
|---|---|---|---|
| Primer design | Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed. | template found | open → |
| BLAST | Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start. | template found | open → |
| Expression heatmap | Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it. | no expression matrix | – |
| Gene family / orthogroup | Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue. | open → | |
| Gene set analysis | Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it. | open → |
