Genomic Location: sc0000116_pilon:275766...341243
NR annotation: XP_029196674.2, dynein axonemal heavy chain 5-like [Acropora millepora]
Species Acropora muricata · all data for this species · gene families
| CDS |
| amur_s0116.g24.t1 |
| Transcript |
| amur_s0116.g24.t1 |
| Protein |
| amur_s0116.g24.t1 |
| UniProt accession | Description |
|---|---|
| Q8TE73 | Dynein axonemal heavy chain 5 OS=Homo sapiens OX=9606 GN=DNAH5 PE=1 SV=3 |
| Q8VHE6 | Dynein axonemal heavy chain 5 OS=Mus musculus OX=10090 GN=Dnah5 PE=1 SV=2 |
| Q91XQ0 | Dynein axonemal heavy chain 8 OS=Mus musculus OX=10090 GN=Dnah8 PE=1 SV=2 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0000599 (this species only) · gene tree & orthology |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF12775 all species → | AAA_7 | P-loop containing dynein motor region | Domain | Interproscan |
| PF08393 all species → | DHC_N2 | Dynein heavy chain, N-terminal region 2 | Family | Interproscan |
| PF17852 all species → | Dynein_AAA_lid | Dynein heavy chain AAA lid domain | Domain | Interproscan |
| PF12777 all species → | MT | Microtubule-binding stalk of dynein motor | Domain | Interproscan |
| PF17857 all species → | AAA_lid_1 | AAA+ lid domain | Domain | Interproscan |
| PF08385 all species → | DHC_N1 | Dynein heavy chain, N-terminal region 1 | Family | Interproscan |
| PF03028 all species → | Dynein_heavy | Dynein heavy chain region D6 P-loop domain | Domain | Interproscan |
| PF18199 all species → | Dynein_C | Dynein heavy chain C-terminal domain | Domain | Interproscan |
| PF12774 all species → | AAA_6 | Hydrolytic ATP binding site of dynein motor region | Domain | Interproscan |
| PF12780 all species → | AAA_8 | P-loop containing dynein motor region D4 | Domain | Interproscan |
| PF18198 all species → | AAA_lid_11 | Dynein heavy chain AAA lid domain | Domain | Interproscan |
| PF12781 all species → | AAA_9 | ATP-binding dynein motor region | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR027417 all species → | Homologous_superfamily | P-loop containing nucleoside triphosphate hydrolase | Interproscan |
| IPR042219 all species → | Homologous_superfamily | Dynein heavy chain AAA lid domain superfamily | Interproscan |
| IPR043160 all species → | Homologous_superfamily | Dynein heavy chain, C-terminal domain, barrel region | Interproscan |
| IPR013602 all species → | Domain | Dynein heavy chain, linker | Interproscan |
| IPR026983 all species → | Family | Dynein heavy chain | Interproscan |
| IPR041466 all species → | Domain | Dynein heavy chain, AAA 5 extension domain | Interproscan |
| IPR024743 all species → | Domain | Dynein heavy chain, coiled coil stalk | Interproscan |
| IPR003593 all species → | Domain | AAA+ ATPase domain | Interproscan |
| IPR043157 all species → | Homologous_superfamily | Dynein heavy chain, AAA1 domain, small subdomain | Interproscan |
| IPR041589 all species → | Domain | Dynein heavy chain 3, AAA+ lid domain | Interproscan |
| IPR013594 all species → | Domain | Dynein heavy chain, tail | Interproscan |
| IPR004273 all species → | Domain | Dynein heavy chain region D6 P-loop domain | Interproscan |
| IPR041228 all species → | Domain | Dynein heavy chain, C-terminal domain | Interproscan |
| IPR042228 all species → | Homologous_superfamily | Dynein heavy chain, linker, subdomain 3 | Interproscan |
| IPR042222 all species → | Homologous_superfamily | Dynein heavy chain, domain 2, N-terminal | Interproscan |
| IPR035699 all species → | Domain | Dynein heavy chain, hydrolytic ATP-binding dynein motor region | Interproscan |
| IPR024317 all species → | Domain | Dynein heavy chain, AAA module D4 | Interproscan |
| IPR041658 all species → | Domain | Dynein heavy chain AAA lid domain | Interproscan |
| IPR035706 all species → | Domain | Dynein heavy chain, ATP-binding dynein motor region | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR46532 all species → | MALE FERTILITY FACTOR KL5 | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0005858 all species → | Cellular Component | axonemal dynein complex | Interproscan |
| GO:0007018 all species → | Biological Process | microtubule-based movement | Interproscan |
| GO:0030286 all species → | Cellular Component | dynein complex | Interproscan |
| GO:0045505 all species → | Molecular Function | dynein intermediate chain binding | Interproscan |
| GO:0051959 all species → | Molecular Function | dynein light intermediate chain binding | Interproscan |
| GO:0016887 all species → | Molecular Function | ATP hydrolysis activity | Interproscan |
| GO:0008569 all species → | Molecular Function | minus-end-directed microtubule motor activity | Interproscan |
| GO:0005524 all species → | Molecular Function | ATP binding | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K10408 | DNAH; dynein axonemal heavy chain | - | Cytoskeleton proteins | ko04812 | deepkoala |
Transcript abundance of amur_s0116.g24.t1 across 82 RNA-seq samples of Acropora muricata. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.
| Condition | Samples | TPM > 0 | Mean TPM | Max TPM | Mean, relative to max |
|---|---|---|---|---|---|
| Polyps | 79 | 73 | 15.97 | 81.02 | |
| Severed branch | 3 | 0 | 0.00 | 0.00 |
| SRA run | Condition | Tissue | Developmental stage | Treatment | Study | TPM |
|---|---|---|---|---|---|---|
| SRR27868165 | Polyps | Polyps | regeneration day3 | not recorded | SRP199550 | 81.02 |
| SRR27868187 | Polyps | Polyps | regeneration day3 | not recorded | SRP199550 | 53.70 |
| SRR27868183 | Polyps | Polyps | regeneration day33 | not recorded | SRP199550 | 41.14 |
| SRR27868176 | Polyps | Polyps | regeneration day3 | not recorded | SRP199550 | 40.77 |
| SRR27868192 | Polyps | Polyps | regeneration day24 | not recorded | SRP199550 | 37.43 |
| SRR27868185 | Polyps | Polyps | regeneration day30 | not recorded | SRP199550 | 35.03 |
| SRR12959204 | Polyps | Polyps | E2 day15 | not recorded | SRP199550 | 34.90 |
| SRR12959205 | Polyps | Polyps | E2 day15 | not recorded | SRP199550 | 34.15 |
| SRR27868205 | Polyps | Polyps | regeneration day12 | not recorded | SRP199550 | 29.39 |
| SRR27868190 | Polyps | Polyps | regeneration day27 | not recorded | SRP199550 | 27.93 |
| SRR27868197 | Polyps | Polyps | regeneration day18 | not recorded | SRP199550 | 27.69 |
| SRR27868189 | Polyps | Polyps | regeneration day27 | not recorded | SRP199550 | 27.31 |
| SRR27868188 | Polyps | Polyps | regeneration day27 | not recorded | SRP199550 | 27.08 |
| SRR12959206 | Polyps | Polyps | E2 day0 | not recorded | SRP199550 | 25.79 |
| SRR27868184 | Polyps | Polyps | regeneration day30 | not recorded | SRP199550 | 24.83 |
| SRR27868200 | Polyps | Polyps | regeneration day18 | not recorded | SRP199550 | 24.70 |
| SRR27868193 | Polyps | Polyps | regeneration day24 | not recorded | SRP199550 | 21.97 |
| SRR27868177 | Polyps | Polyps | regeneration day39 | not recorded | SRP199550 | 21.91 |
| SRR27940225 | Polyps | Polyps | not recorded | not recorded | SRP199550 | 21.16 |
| SRR27868199 | Polyps | Polyps | regeneration day18 | not recorded | SRP199550 | 20.78 |
| SRR27868181 | Polyps | Polyps | regeneration day33 | not recorded | SRP199550 | 20.50 |
| SRR27868186 | Polyps | Polyps | regeneration day30 | not recorded | SRP199550 | 20.13 |
| SRR12959195 | Polyps | Polyps | E2 day0 | not recorded | SRP199550 | 19.73 |
| SRR27868208 | Polyps | Polyps | regeneration day9 | not recorded | SRP199550 | 19.06 |
| SRR27868207 | Polyps | Polyps | regeneration day9 | not recorded | SRP199550 | 18.85 |
| SRR27868201 | Polyps | Polyps | regeneration day15 | not recorded | SRP199550 | 18.75 |
| SRR12959217 | Polyps | Polyps | E2 day0 | not recorded | SRP199550 | 18.70 |
| SRR27868174 | Polyps | Polyps | regeneration day39 | not recorded | SRP199550 | 18.55 |
| SRR27868182 | Polyps | Polyps | regeneration day33 | not recorded | SRP199550 | 18.37 |
| SRR27868203 | Polyps | Polyps | regeneration day15 | not recorded | SRP199550 | 18.20 |
| SRR27868179 | Polyps | Polyps | regeneration day36 | not recorded | SRP199550 | 16.91 |
| SRR27868180 | Polyps | Polyps | regeneration day36 | not recorded | SRP199550 | 16.65 |
| SRR27868159 | Polyps | Polyps | regeneration day6 | not recorded | SRP199550 | 16.04 |
| SRR27868202 | Polyps | Polyps | regeneration day15 | not recorded | SRP199550 | 15.49 |
| SRR27868204 | Polyps | Polyps | regeneration day12 | not recorded | SRP199550 | 14.67 |
| SRR12959218 | Polyps | Polyps | E2 day9 | not recorded | SRP199550 | 14.47 |
| SRR27868175 | Polyps | Polyps | regeneration day39 | not recorded | SRP199550 | 14.25 |
| SRR12959219 | Polyps | Polyps | E2 day9 | not recorded | SRP199550 | 14.12 |
| SRR27868209 | Polyps | Polyps | regeneration day0 | not recorded | SRP199550 | 14.03 |
| SRR12959220 | Polyps | Polyps | E2 day9 | not recorded | SRP199550 | 13.77 |
| SRR12904785 | Polyps | Polyps | not recorded | not recorded | SRP199550 | 13.58 |
| SRR27868206 | Polyps | Polyps | regeneration day12 | not recorded | SRP199550 | 13.31 |
| SRR27868158 | Polyps | Polyps | regeneration day6 | not recorded | SRP199550 | 12.98 |
| SRR27868160 | Polyps | Polyps | regeneration day6 | not recorded | SRP199550 | 12.50 |
| SRR27868194 | Polyps | Polyps | regeneration day21 | not recorded | SRP199550 | 12.22 |
| SRR12959231 | Polyps | Polyps | E2 day3 | not recorded | SRP199550 | 12.10 |
| SRR27868178 | Polyps | Polyps | regeneration day36 | not recorded | SRP199550 | 12.07 |
| SRR27940224 | Polyps | Polyps | not recorded | not recorded | SRP199550 | 11.52 |
| SRR12904784 | Polyps | Polyps | not recorded | not recorded | SRP199550 | 11.37 |
| SRR12959233 | Polyps | Polyps | E2 day3 | not recorded | SRP199550 | 11.27 |
| SRR12959207 | Polyps | Polyps | E2 day15 | not recorded | SRP199550 | 10.17 |
| SRR12959232 | Polyps | Polyps | E2 day3 | not recorded | SRP199550 | 10.05 |
| SRR12959191 | Polyps | polyps | E2 day21 | not recorded | SRP199550 | 9.56 |
| SRR12959192 | Polyps | Polyps | E2 day21 | not recorded | SRP199550 | 9.45 |
| SRR12959193 | Polyps | Polyps | E2 day21 | not recorded | SRP199550 | 9.33 |
| SRR27940226 | Polyps | Polyps | not recorded | not recorded | SRP199550 | 8.02 |
| SRR27940222 | Polyps | Polyps | not recorded | not recorded | SRP199550 | 7.29 |
| SRR27868198 | Polyps | Polyps | regeneration day0 | not recorded | SRP199550 | 7.02 |
| SRR27868195 | Polyps | Polyps | regeneration day21 | not recorded | SRP199550 | 6.80 |
| SRR12786900 | Polyps | Polyps | OA 2 day0 | not recorded | SRP199550 | 5.96 |
| SRR27940227 | Polyps | Polyps | not recorded | not recorded | SRP199550 | 5.91 |
| SRR12786899 | Polyps | Polyps | OA 2 day0 | not recorded | SRP199550 | 5.42 |
| SRR12786901 | Polyps | Polyps | OA 2 day0 | not recorded | SRP199550 | 5.15 |
| SRR12710850 | Polyps | Polyps | OA 2 day3 | not recorded | SRP199550 | 4.80 |
| SRR12710851 | Polyps | Polyps | OA 2 day3 | not recorded | SRP199550 | 4.16 |
| SRR12710849 | Polyps | Polyps | OA 2 day3 | not recorded | SRP199550 | 4.11 |
| SRR27868196 | Polyps | Polyps | regeneration day21 | not recorded | SRP199550 | 4.09 |
| SRR27868210 | Polyps | Polyps | regeneration day0 | not recorded | SRP199550 | 3.92 |
| SRR27940228 | Polyps | Polyps | not recorded | not recorded | SRP199550 | 3.92 |
| SRR12904786 | Polyps | Polyps | not recorded | not recorded | SRP199550 | 3.87 |
| SRR12710860 | Polyps | Polyps | OA 2 day9 | not recorded | SRP199550 | 3.52 |
| SRR12710861 | Polyps | Polyps | OA 2 day9 | not recorded | SRP199550 | 3.38 |
| SRR12710859 | Polyps | Polyps | OA 2 day9 | not recorded | SRP199550 | 2.84 |
| SRR12807382 | Polyps | Polyps | OA2 day0 | not recorded | SRP199550 | 0.00 |
| SRR12927881 | Polyps | Polyps | E2 day0 | not recorded | SRP199550 | 0.00 |
| SRR27868191 | Polyps | Polyps | regeneration day24 | not recorded | SRP199550 | 0.00 |
| SRR27940229 | Polyps | Polyps | not recorded | not recorded | SRP199550 | 0.00 |
| SRR9613488 | Polyps | Polyps | not recorded | not recorded | SRP199550 | 0.00 |
| SRR9613516 | Polyps | Polyps | not recorded | not recorded | SRP199550 | 0.00 |
| SRR12995717 | Severed branch | Severed branch | regeneration day0 | not recorded | SRP199550 | 0.00 |
| SRR12996627 | Severed branch | Severed branch | regeneration day0 | not recorded | SRP199550 | 0.00 |
| SRR12996628 | Severed branch | Severed branch | regeneration High gene expression | not recorded | SRP199550 | 0.00 |
Source: CnidoSite RNA-seq expression matrices (AMURI_TPM,
StringTie quantification over 82 runs), joined to SRA sample
metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped
by the descriptor carried in the expression matrix itself.
Genes whose expression across the transcriptome samples of Acropora muricata tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.
| Direction | Partners | Most correlated partner | PCC |
|---|---|---|---|
| Positively correlated | 35 | amur_s0009.g56.t1 | 0.857674469942889 |
| Negatively correlated | 5 | amur_s0122.g17.t1 | -0.341764623820116 |
Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list.
Whether this gene can be visualised in the single-cell atlases of Acropora muricata, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.
| Dataset | Tissue / stage | Cells | Cell types | This gene | Marker of |
|---|---|---|---|---|---|
| AMURI_regen | Polyps · regeneration | 8,721 | 28 | unmapped | – |
A gene is in viewer when the dataset ships a per-cell expression vector for it; marker only means it is in the dataset’s ranked marker table but no vector was exported, so the atlas cannot draw it; not in this dataset means the dataset’s own gene-ID table does not list it, so no expression claim can be made for that dataset. unmapped is deliberately weaker still: the dataset has no gene-ID table on CnidoSite yet, so nothing is claimed in either direction. Where markers are listed, the numbers are log2 fold change and the percentage of cells of that type in which the gene was detected.
Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.
No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.
Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.
| Analysis | What it does | Status | |
|---|---|---|---|
| Primer design | Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed. | template found | open → |
| BLAST | Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start. | template found | open → |
| Expression heatmap | Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it. | ready | open → |
| Gene family / orthogroup | Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue. | open → | |
| Gene set analysis | Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it. | open → |