Detailed information of amur_s0229.g69.t1 in Acropora muricata

Genomic Location: sc0000229_pilon:848479...877497
NR annotation: XP_029195436.2, pre-mRNA-processing-splicing factor 8 [Acropora millepora]
Species Acropora muricata · all data for this species · gene families


 Gene Structure
More details in JBrowse  Sequence
CDS
Transcript
Protein
 UniProt (Swiss-Prot top hit)
UniProt accessionDescription
Q6P2Q9Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2
Q99PV0Pre-mRNA-processing-splicing factor 8 OS=Mus musculus OX=10090 GN=Prpf8 PE=1 SV=2
P34369Pre-mRNA-splicing factor 8 homolog OS=Caenorhabditis elegans OX=6239 GN=prp-8 PE=1 SV=1
 Gene family
Family typeMembership / link
Orthogroup (gene family)OG0004368 (this species only) · gene tree & orthology
Ubiquitin familyUBD|Other|Jab_MPN · all ubiquitin genes in this species

 Pfam domain
Pfam accessionPfam nameDescriptionTypeSource
PF08082
all species →
PRO8NTPRO8NT (NUC069), PrP8 N-terminal domainDomainInterproscan
PF10598
all species →
RRM_4RNA recognition motif of the spliceosomal PrP8DomainInterproscan
PF12134
all species →
PRP8_domainIVPRP8 domain IV coreDomainInterproscan
PF08083
all species →
PROCNPROCN (NUC071) domainDomainInterproscan
PF10597
all species →
U5_2-snRNA_bdgU5-snRNA binding site 2 of PrP8DomainInterproscan
PF01398
all species →
JABJAB1/Mov34/MPN/PAD-1 ubiquitin proteaseFamilyInterproscan
PF10596
all species →
U6-snRNA_bdgU6-snRNA interacting domain of PrP8DomainInterproscan
PF08084
all species →
PROCTPROCT (NUC072) domainDomainInterproscan

 InterPro
InterPro termTypeDescriptionSource
IPR012591
all species →
DomainPRO8NT domainInterproscan
IPR019582
all species →
DomainRNA recognition motif, spliceosomal PrP8Interproscan
IPR012337
all species →
Homologous_superfamilyRibonuclease H-like superfamilyInterproscan
IPR021983
all species →
DomainPRP8 domain IV coreInterproscan
IPR012592
all species →
DomainPROCN domainInterproscan
IPR019581
all species →
DomainPre-mRNA-processing-splicing factor 8, U5-snRNA-bindingInterproscan
IPR000555
all species →
DomainJAB1/MPN/MOV34 metalloenzyme domainInterproscan
IPR019580
all species →
DomainPre-mRNA-processing-splicing factor 8, U6-snRNA-bindingInterproscan
IPR027652
all species →
FamilyPre-mRNA-processing-splicing factor 8Interproscan
IPR042516
all species →
Homologous_superfamilyPre-mRNA-processing-splicing factor 8, U5-snRNA-binding domain superfamilyInterproscan
IPR037518
all species →
DomainMPN domainInterproscan
IPR043172
all species →
Homologous_superfamilyPrp8 RNase domain IV, palm regionInterproscan
IPR043173
all species →
Homologous_superfamilyPrp8 RNase domain IV, fingers regionInterproscan
IPR012984
all species →
DomainPROCT domainInterproscan

 PANTHER
PANTHER termDescriptionSource
PTHR11140
all species →
PRE-MRNA SPLICING FACTOR PRP8Interproscan

 Gene Ontology
GO termCategoryDescriptionSource
GO:0000398
all species →
Biological ProcessmRNA splicing, via spliceosomeInterproscan
GO:0003723
all species →
Molecular FunctionRNA bindingInterproscan
GO:0030623
all species →
Molecular FunctionU5 snRNA bindingInterproscan
GO:0005515
all species →
Molecular Functionprotein bindingInterproscan
GO:0008233
all species →
Molecular Functionpeptidase activityInterproscan
GO:0008237
all species →
Molecular Functionmetallopeptidase activityInterproscan
GO:0017070
all species →
Molecular FunctionU6 snRNA bindingInterproscan
GO:0000244
all species →
Biological Processspliceosomal tri-snRNP complex assemblyInterproscan
GO:0005681
all species →
Cellular Componentspliceosomal complexInterproscan
GO:0005682
all species →
Cellular ComponentU5 snRNPInterproscan
GO:0030619
all species →
Molecular FunctionU1 snRNA bindingInterproscan
GO:0030620
all species →
Molecular FunctionU2 snRNA bindingInterproscan
GO:0071013
all species →
Cellular Componentcatalytic step 2 spliceosomeInterproscan
GO:0097157
all species →
Molecular Functionpre-mRNA intronic bindingInterproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.
 KEGG pathway
KOEnzymeEnzyme IDPathwayMap IDSource
K12856PRPF8, PRP8; pre-mRNA-processing factor 8-Spliceosomeko03041deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of amur_s0229.g69.t1 across 82 RNA-seq samples of Acropora muricata. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

82Samples
74TPM > 0
2Conditions
359.5Max TPM
47.3Mean TPM

By condition

ConditionSamplesTPM > 0 Mean TPMMax TPMMean, relative to max
Polyps 79 74 49.08 359.49
Severed branch 3 0 0.00 0.00

Per sample · hover a bar for the full sample record

Show the sample table (82 samples)
SRA runConditionTissueDevelopmental stage TreatmentStudyTPM
SRR27868191 Polyps Polyps regeneration day24 not recorded SRP199550 359.49
SRR12959207 Polyps Polyps E2 day15 not recorded SRP199550 115.74
SRR27868175 Polyps Polyps regeneration day39 not recorded SRP199550 113.93
SRR27868165 Polyps Polyps regeneration day3 not recorded SRP199550 92.31
SRR27868187 Polyps Polyps regeneration day3 not recorded SRP199550 85.40
SRR27868201 Polyps Polyps regeneration day15 not recorded SRP199550 81.98
SRR27940225 Polyps Polyps not recorded not recorded SRP199550 81.77
SRR27868192 Polyps Polyps regeneration day24 not recorded SRP199550 80.32
SRR27868176 Polyps Polyps regeneration day3 not recorded SRP199550 79.62
SRR27868199 Polyps Polyps regeneration day18 not recorded SRP199550 76.02
SRR27868189 Polyps Polyps regeneration day27 not recorded SRP199550 75.39
SRR12959205 Polyps Polyps E2 day15 not recorded SRP199550 74.68
SRR12959204 Polyps Polyps E2 day15 not recorded SRP199550 73.87
SRR27868188 Polyps Polyps regeneration day27 not recorded SRP199550 73.49
SRR27868183 Polyps Polyps regeneration day33 not recorded SRP199550 72.54
SRR27868186 Polyps Polyps regeneration day30 not recorded SRP199550 69.90
SRR27868193 Polyps Polyps regeneration day24 not recorded SRP199550 69.73
SRR27868185 Polyps Polyps regeneration day30 not recorded SRP199550 68.77
SRR27868197 Polyps Polyps regeneration day18 not recorded SRP199550 66.66
SRR12959206 Polyps Polyps E2 day0 not recorded SRP199550 66.02
SRR27868200 Polyps Polyps regeneration day18 not recorded SRP199550 65.04
SRR27868205 Polyps Polyps regeneration day12 not recorded SRP199550 64.29
SRR27868182 Polyps Polyps regeneration day33 not recorded SRP199550 63.71
SRR27868203 Polyps Polyps regeneration day15 not recorded SRP199550 63.47
SRR27868190 Polyps Polyps regeneration day27 not recorded SRP199550 63.22
SRR27868180 Polyps Polyps regeneration day36 not recorded SRP199550 61.98
SRR12959195 Polyps Polyps E2 day0 not recorded SRP199550 59.28
SRR27868207 Polyps Polyps regeneration day9 not recorded SRP199550 58.96
SRR27868208 Polyps Polyps regeneration day9 not recorded SRP199550 58.05
SRR27868184 Polyps Polyps regeneration day30 not recorded SRP199550 57.50
SRR27868202 Polyps Polyps regeneration day15 not recorded SRP199550 56.44
SRR12959217 Polyps Polyps E2 day0 not recorded SRP199550 55.99
SRR27868174 Polyps Polyps regeneration day39 not recorded SRP199550 55.25
SRR27868160 Polyps Polyps regeneration day6 not recorded SRP199550 49.83
SRR27868179 Polyps Polyps regeneration day36 not recorded SRP199550 48.82
SRR12904785 Polyps Polyps not recorded not recorded SRP199550 45.86
SRR27868209 Polyps Polyps regeneration day0 not recorded SRP199550 45.73
SRR12959232 Polyps Polyps E2 day3 not recorded SRP199550 42.92
SRR27868194 Polyps Polyps regeneration day21 not recorded SRP199550 41.60
SRR27868158 Polyps Polyps regeneration day6 not recorded SRP199550 41.50
SRR27868181 Polyps Polyps regeneration day33 not recorded SRP199550 41.22
SRR27868204 Polyps Polyps regeneration day12 not recorded SRP199550 41.03
SRR12959220 Polyps Polyps E2 day9 not recorded SRP199550 40.84
SRR12904784 Polyps Polyps not recorded not recorded SRP199550 40.75
SRR27940224 Polyps Polyps not recorded not recorded SRP199550 40.74
SRR27868198 Polyps Polyps regeneration day0 not recorded SRP199550 39.73
SRR12959218 Polyps Polyps E2 day9 not recorded SRP199550 39.21
SRR27868206 Polyps Polyps regeneration day12 not recorded SRP199550 37.36
SRR27940226 Polyps Polyps not recorded not recorded SRP199550 37.10
SRR12959219 Polyps Polyps E2 day9 not recorded SRP199550 37.06
SRR12959233 Polyps Polyps E2 day3 not recorded SRP199550 35.52
SRR12959231 Polyps Polyps E2 day3 not recorded SRP199550 35.13
SRR12959191 Polyps polyps E2 day21 not recorded SRP199550 31.63
SRR12959192 Polyps Polyps E2 day21 not recorded SRP199550 31.23
SRR27868178 Polyps Polyps regeneration day36 not recorded SRP199550 31.08
SRR12959193 Polyps Polyps E2 day21 not recorded SRP199550 29.51
SRR27868177 Polyps Polyps regeneration day39 not recorded SRP199550 27.28
SRR27868159 Polyps Polyps regeneration day6 not recorded SRP199550 24.84
SRR12786900 Polyps Polyps OA 2 day0 not recorded SRP199550 24.33
SRR12786899 Polyps Polyps OA 2 day0 not recorded SRP199550 22.73
SRR12786901 Polyps Polyps OA 2 day0 not recorded SRP199550 20.76
SRR27868195 Polyps Polyps regeneration day21 not recorded SRP199550 18.95
SRR27940222 Polyps Polyps not recorded not recorded SRP199550 18.24
SRR27868210 Polyps Polyps regeneration day0 not recorded SRP199550 17.55
SRR27940228 Polyps Polyps not recorded not recorded SRP199550 17.54
SRR12904786 Polyps Polyps not recorded not recorded SRP199550 17.45
SRR12710849 Polyps Polyps OA 2 day3 not recorded SRP199550 16.45
SRR12710850 Polyps Polyps OA 2 day3 not recorded SRP199550 15.55
SRR27868196 Polyps Polyps regeneration day21 not recorded SRP199550 14.62
SRR12710851 Polyps Polyps OA 2 day3 not recorded SRP199550 14.42
SRR12710860 Polyps Polyps OA 2 day9 not recorded SRP199550 11.47
SRR12710859 Polyps Polyps OA 2 day9 not recorded SRP199550 10.24
SRR12710861 Polyps Polyps OA 2 day9 not recorded SRP199550 9.86
SRR27940227 Polyps Polyps not recorded not recorded SRP199550 8.93
SRR12807382 Polyps Polyps OA2 day0 not recorded SRP199550 0.00
SRR12927881 Polyps Polyps E2 day0 not recorded SRP199550 0.00
SRR27940229 Polyps Polyps not recorded not recorded SRP199550 0.00
SRR9613488 Polyps Polyps not recorded not recorded SRP199550 0.00
SRR9613516 Polyps Polyps not recorded not recorded SRP199550 0.00
SRR12995717 Severed branch Severed branch regeneration day0 not recorded SRP199550 0.00
SRR12996627 Severed branch Severed branch regeneration day0 not recorded SRP199550 0.00
SRR12996628 Severed branch Severed branch regeneration High gene expression not recorded SRP199550 0.00

Source: CnidoSite RNA-seq expression matrices (AMURI_TPM, StringTie quantification over 82 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.

Co-expression network

Genes whose expression across the transcriptome samples of Acropora muricata tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

DirectionPartnersMost correlated partnerPCC
Positively correlated46amur_s0029.g40.t10.941280730369269
Negatively correlated14amur_s2201.g1.t1-0.331487537212623

Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Acropora muricata, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

DatasetTissue / stageCellsCell typesThis geneMarker of
AMURI_regenPolyps · regeneration8,72128unmapped

A gene is in viewer when the dataset ships a per-cell expression vector for it; marker only means it is in the dataset’s ranked marker table but no vector was exported, so the atlas cannot draw it; not in this dataset means the dataset’s own gene-ID table does not list it, so no expression claim can be made for that dataset. unmapped is deliberately weaker still: the dataset has no gene-ID table on CnidoSite yet, so nothing is claimed in either direction. Where markers are listed, the numbers are log2 fold change and the percentage of cells of that type in which the gene was detected.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

AnalysisWhat it doesStatus
Primer designDesign PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.template foundopen →
BLASTSearch this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.template foundopen →
Expression heatmapDraw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.readyopen →
Gene family / orthogroupLook this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.open →
Gene set analysisStart a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.open →
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