Detailed information of amur_s0322.g1.t1 in Acropora muricata

Genomic Location: sc0000322_pilon:1...39775
NR annotation: XP_029180573.2, CAD protein-like [Acropora millepora]
Species Acropora muricata · all data for this species · gene families


 Gene Structure
More details in JBrowse  Sequence
CDS
Transcript
Protein
 UniProt (Swiss-Prot top hit)
UniProt accessionDescription
Q91437Multifunctional protein CAD OS=Squalus acanthias OX=7797 GN=CAD PE=2 SV=1
B2RQC6Multifunctional protein CAD OS=Mus musculus OX=10090 GN=Cad PE=1 SV=1
P27708Multifunctional protein CAD OS=Homo sapiens OX=9606 GN=CAD PE=1 SV=3
 Gene family
Family typeMembership / link
Orthogroup (gene family)OG0001105 (this species only) · gene tree & orthology

 Pfam domain
Pfam accessionPfam nameDescriptionTypeSource
PF02142
all species →
MGSMGS-like domainDomainInterproscan
PF02787
all species →
CPSase_L_D3Carbamoyl-phosphate synthetase large chain, oligomerisation domainDomainInterproscan
PF00185
all species →
OTCaceAspartate/ornithine carbamoyltransferase, Asp/Orn binding domainDomainInterproscan
PF00988
all species →
CPSase_sm_chainCarbamoyl-phosphate synthase small chain, CPSase domainDomainInterproscan
PF02786
all species →
CPSase_L_D2Carbamoyl-phosphate synthase L chain, ATP binding domainDomainInterproscan
PF01979
all species →
Amidohydro_1Amidohydrolase familyDomainInterproscan
PF00117
all species →
GATaseGlutamine amidotransferase class-IDomainInterproscan
PF02729
all species →
OTCace_NAspartate/ornithine carbamoyltransferase, carbamoyl-P binding domainDomainInterproscan

 InterPro
InterPro termTypeDescriptionSource
IPR032466
all species →
Homologous_superfamilyMetal-dependent hydrolaseInterproscan
IPR016185
all species →
Homologous_superfamilyPre-ATP-grasp domain superfamilyInterproscan
IPR011607
all species →
DomainMethylglyoxal synthase-like domainInterproscan
IPR036901
all species →
Homologous_superfamilyAspartate/ornithine carbamoyltransferase superfamilyInterproscan
IPR005479
all species →
DomainCarbamoyl-phosphate synthetase large subunit-like, ATP-binding domainInterproscan
IPR036914
all species →
Homologous_superfamilyMethylglyoxal synthase-like domain superfamilyInterproscan
IPR002195
all species →
Conserved_siteDihydroorotase, conserved siteInterproscan
IPR036480
all species →
Homologous_superfamilyCarbamoyl-phosphate synthase small subunit, N-terminal domain superfamilyInterproscan
IPR035686
all species →
DomainCarbamoyl-phosphate synthase small subunit, GATase1 domainInterproscan
IPR006274
all species →
FamilyCarbamoyl-phosphate synthase, small subunitInterproscan
IPR005480
all species →
DomainCarbamoyl-phosphate synthetase, large subunit oligomerisation domainInterproscan
IPR011059
all species →
Homologous_superfamilyMetal-dependent hydrolase, composite domain superfamilyInterproscan
IPR006131
all species →
DomainAspartate/ornithine carbamoyltransferase, Asp/Orn-binding domainInterproscan
IPR029062
all species →
Homologous_superfamilyClass I glutamine amidotransferase-likeInterproscan
IPR002474
all species →
DomainCarbamoyl-phosphate synthase small subunit, N-terminal domainInterproscan
IPR006130
all species →
FamilyAspartate/ornithine carbamoyltransferaseInterproscan
IPR036897
all species →
Homologous_superfamilyCarbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamilyInterproscan
IPR005483
all species →
DomainCarbamoyl-phosphate synthase large subunit, CPSase domainInterproscan
IPR011761
all species →
DomainATP-grasp foldInterproscan
IPR006680
all species →
DomainAmidohydrolase-relatedInterproscan
IPR006275
all species →
FamilyCarbamoyl-phosphate synthase, large subunitInterproscan
IPR002082
all species →
FamilyAspartate carbamoyltransferaseInterproscan
IPR017926
all species →
DomainGlutamine amidotransferaseInterproscan
IPR013815
all species →
Homologous_superfamilyATP-grasp fold, subdomain 1Interproscan
IPR006132
all species →
DomainAspartate/ornithine carbamoyltransferase, carbamoyl-P bindingInterproscan

 PANTHER
PANTHER termDescriptionSource
PTHR11405
all species →
CARBAMOYLTRANSFERASE FAMILY MEMBERInterproscan

 Gene Ontology
GO termCategoryDescriptionSource
GO:0006520
all species →
Biological Processamino acid metabolic processInterproscan
GO:0016597
all species →
Molecular Functionamino acid bindingInterproscan
GO:0016743
all species →
Molecular Functioncarboxyl- or carbamoyltransferase activityInterproscan
GO:0005524
all species →
Molecular FunctionATP bindingInterproscan
GO:0016812
all species →
Molecular Functionhydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidesInterproscan
GO:0004088
all species →
Molecular Functioncarbamoyl-phosphate synthase (glutamine-hydrolyzing) activityInterproscan
GO:0006207
all species →
Biological Process'de novo' pyrimidine nucleobase biosynthetic processInterproscan
GO:0006541
all species →
Biological Processglutamine metabolic processInterproscan
GO:0016810
all species →
Molecular Functionhydrolase activity, acting on carbon-nitrogen (but not peptide) bondsInterproscan
GO:0006807
all species →
Biological Processobsolete nitrogen compound metabolic processInterproscan
GO:0046872
all species →
Molecular Functionmetal ion bindingInterproscan
GO:0016787
all species →
Molecular Functionhydrolase activityInterproscan
GO:0004070
all species →
Molecular Functionaspartate carbamoyltransferase activityInterproscan
GO:0004151
all species →
Molecular Functiondihydroorotase activityInterproscan
GO:0005737
all species →
Cellular ComponentcytoplasmInterproscan
GO:0005829
all species →
Cellular ComponentcytosolInterproscan
GO:0006228
all species →
Biological ProcessUTP biosynthetic processInterproscan
GO:0019240
all species →
Biological Processcitrulline biosynthetic processInterproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.
 KEGG pathway
KOEnzymeEnzyme IDPathwayMap IDSource
K11540CAD; carbamoyl-phosphate synthase / aspartate carbamoyltransferase / dihydroorotaseEC:6.3.5.5
EC:2.1.3.2
EC:3.5.2.3
Peptidases and inhibitorsko01002deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of amur_s0322.g1.t1 across 82 RNA-seq samples of Acropora muricata. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

82Samples
67TPM > 0
2Conditions
131.2Max TPM
7.0Mean TPM

By condition

ConditionSamplesTPM > 0 Mean TPMMax TPMMean, relative to max
Polyps 79 67 7.27 131.17
Severed branch 3 0 0.00 0.00

Per sample · hover a bar for the full sample record

Show the sample table (82 samples)
SRA runConditionTissueDevelopmental stage TreatmentStudyTPM
SRR27868191 Polyps Polyps regeneration day24 not recorded SRP199550 131.17
SRR27868182 Polyps Polyps regeneration day33 not recorded SRP199550 21.54
SRR27868192 Polyps Polyps regeneration day24 not recorded SRP199550 16.01
SRR27868187 Polyps Polyps regeneration day3 not recorded SRP199550 15.12
SRR27868199 Polyps Polyps regeneration day18 not recorded SRP199550 13.45
SRR27868183 Polyps Polyps regeneration day33 not recorded SRP199550 13.41
SRR27868202 Polyps Polyps regeneration day15 not recorded SRP199550 13.32
SRR27868176 Polyps Polyps regeneration day3 not recorded SRP199550 13.26
SRR27868203 Polyps Polyps regeneration day15 not recorded SRP199550 13.20
SRR27868201 Polyps Polyps regeneration day15 not recorded SRP199550 12.47
SRR27868159 Polyps Polyps regeneration day6 not recorded SRP199550 11.72
SRR27868181 Polyps Polyps regeneration day33 not recorded SRP199550 11.70
SRR27868197 Polyps Polyps regeneration day18 not recorded SRP199550 11.12
SRR27868188 Polyps Polyps regeneration day27 not recorded SRP199550 10.89
SRR27868189 Polyps Polyps regeneration day27 not recorded SRP199550 10.78
SRR27868184 Polyps Polyps regeneration day30 not recorded SRP199550 10.39
SRR27868200 Polyps Polyps regeneration day18 not recorded SRP199550 9.92
SRR27868180 Polyps Polyps regeneration day36 not recorded SRP199550 9.75
SRR27868178 Polyps Polyps regeneration day36 not recorded SRP199550 9.36
SRR27868177 Polyps Polyps regeneration day39 not recorded SRP199550 9.31
SRR12959195 Polyps Polyps E2 day0 not recorded SRP199550 9.05
SRR12959204 Polyps Polyps E2 day15 not recorded SRP199550 8.95
SRR27868185 Polyps Polyps regeneration day30 not recorded SRP199550 8.92
SRR12959217 Polyps Polyps E2 day0 not recorded SRP199550 8.61
SRR12959205 Polyps Polyps E2 day15 not recorded SRP199550 7.68
SRR27868207 Polyps Polyps regeneration day9 not recorded SRP199550 7.58
SRR27868205 Polyps Polyps regeneration day12 not recorded SRP199550 7.32
SRR27868208 Polyps Polyps regeneration day9 not recorded SRP199550 7.23
SRR27868158 Polyps Polyps regeneration day6 not recorded SRP199550 6.91
SRR27868204 Polyps Polyps regeneration day12 not recorded SRP199550 6.81
SRR27868174 Polyps Polyps regeneration day39 not recorded SRP199550 6.51
SRR27868179 Polyps Polyps regeneration day36 not recorded SRP199550 6.05
SRR27868198 Polyps Polyps regeneration day0 not recorded SRP199550 5.93
SRR27868209 Polyps Polyps regeneration day0 not recorded SRP199550 5.82
SRR27868193 Polyps Polyps regeneration day24 not recorded SRP199550 5.80
SRR27868194 Polyps Polyps regeneration day21 not recorded SRP199550 5.59
SRR12904785 Polyps Polyps not recorded not recorded SRP199550 5.57
SRR12959218 Polyps Polyps E2 day9 not recorded SRP199550 5.41
SRR12959219 Polyps Polyps E2 day9 not recorded SRP199550 5.09
SRR12959220 Polyps Polyps E2 day9 not recorded SRP199550 5.09
SRR27868160 Polyps Polyps regeneration day6 not recorded SRP199550 4.42
SRR12959206 Polyps Polyps E2 day0 not recorded SRP199550 4.41
SRR12959192 Polyps Polyps E2 day21 not recorded SRP199550 4.34
SRR27940224 Polyps Polyps not recorded not recorded SRP199550 4.03
SRR12904784 Polyps Polyps not recorded not recorded SRP199550 4.01
SRR27868206 Polyps Polyps regeneration day12 not recorded SRP199550 3.99
SRR12959191 Polyps polyps E2 day21 not recorded SRP199550 3.74
SRR27868190 Polyps Polyps regeneration day27 not recorded SRP199550 3.50
SRR27940222 Polyps Polyps not recorded not recorded SRP199550 3.45
SRR12959233 Polyps Polyps E2 day3 not recorded SRP199550 3.41
SRR12959231 Polyps Polyps E2 day3 not recorded SRP199550 3.19
SRR12959232 Polyps Polyps E2 day3 not recorded SRP199550 3.19
SRR12959193 Polyps Polyps E2 day21 not recorded SRP199550 2.91
SRR12786900 Polyps Polyps OA 2 day0 not recorded SRP199550 2.82
SRR12786901 Polyps Polyps OA 2 day0 not recorded SRP199550 2.28
SRR12786899 Polyps Polyps OA 2 day0 not recorded SRP199550 2.01
SRR27868195 Polyps Polyps regeneration day21 not recorded SRP199550 1.94
SRR12710850 Polyps Polyps OA 2 day3 not recorded SRP199550 1.93
SRR27868210 Polyps Polyps regeneration day0 not recorded SRP199550 1.79
SRR27940228 Polyps Polyps not recorded not recorded SRP199550 1.79
SRR12904786 Polyps Polyps not recorded not recorded SRP199550 1.77
SRR27868196 Polyps Polyps regeneration day21 not recorded SRP199550 1.36
SRR12710849 Polyps Polyps OA 2 day3 not recorded SRP199550 1.14
SRR12710851 Polyps Polyps OA 2 day3 not recorded SRP199550 1.01
SRR12710861 Polyps Polyps OA 2 day9 not recorded SRP199550 0.72
SRR12710860 Polyps Polyps OA 2 day9 not recorded SRP199550 0.63
SRR12710859 Polyps Polyps OA 2 day9 not recorded SRP199550 0.57
SRR12807382 Polyps Polyps OA2 day0 not recorded SRP199550 0.00
SRR12927881 Polyps Polyps E2 day0 not recorded SRP199550 0.00
SRR12959207 Polyps Polyps E2 day15 not recorded SRP199550 0.00
SRR27868165 Polyps Polyps regeneration day3 not recorded SRP199550 0.00
SRR27868175 Polyps Polyps regeneration day39 not recorded SRP199550 0.00
SRR27868186 Polyps Polyps regeneration day30 not recorded SRP199550 0.00
SRR27940225 Polyps Polyps not recorded not recorded SRP199550 0.00
SRR27940226 Polyps Polyps not recorded not recorded SRP199550 0.00
SRR27940227 Polyps Polyps not recorded not recorded SRP199550 0.00
SRR27940229 Polyps Polyps not recorded not recorded SRP199550 0.00
SRR9613488 Polyps Polyps not recorded not recorded SRP199550 0.00
SRR9613516 Polyps Polyps not recorded not recorded SRP199550 0.00
SRR12995717 Severed branch Severed branch regeneration day0 not recorded SRP199550 0.00
SRR12996627 Severed branch Severed branch regeneration day0 not recorded SRP199550 0.00
SRR12996628 Severed branch Severed branch regeneration High gene expression not recorded SRP199550 0.00

Source: CnidoSite RNA-seq expression matrices (AMURI_TPM, StringTie quantification over 82 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.

Co-expression network

Genes whose expression across the transcriptome samples of Acropora muricata tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

DirectionPartnersMost correlated partnerPCC
Positively correlated17amur_s0008.g154.t10.967824712021404
Negatively correlated12amur_s0478.g8.t1-0.277159054002809

Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Acropora muricata, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

DatasetTissue / stageCellsCell typesThis geneMarker of
AMURI_regenPolyps · regeneration8,72128unmapped

A gene is in viewer when the dataset ships a per-cell expression vector for it; marker only means it is in the dataset’s ranked marker table but no vector was exported, so the atlas cannot draw it; not in this dataset means the dataset’s own gene-ID table does not list it, so no expression claim can be made for that dataset. unmapped is deliberately weaker still: the dataset has no gene-ID table on CnidoSite yet, so nothing is claimed in either direction. Where markers are listed, the numbers are log2 fold change and the percentage of cells of that type in which the gene was detected.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

AnalysisWhat it doesStatus
Primer designDesign PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.template foundopen →
BLASTSearch this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.template foundopen →
Expression heatmapDraw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.readyopen →
Gene family / orthogroupLook this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.open →
Gene set analysisStart a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.open →
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