Detailed information of amur_s0322.g23.t1 in Acropora muricata

Genomic Location: sc0000322_pilon:378487...386685
NR annotation: XP_044170171.1, malate dehydrogenase, mitochondrial-like [Acropora millepora]
Species Acropora muricata · all data for this species · gene families


 Gene Structure
More details in JBrowse  Sequence
CDS
Transcript
Protein
 UniProt (Swiss-Prot top hit)
UniProt accessionDescription
P04636Malate dehydrogenase, mitochondrial OS=Rattus norvegicus OX=10116 GN=Mdh2 PE=1 SV=2
Q5NVR2Malate dehydrogenase, mitochondrial OS=Pongo abelii OX=9601 GN=MDH2 PE=2 SV=1
P40926Malate dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=MDH2 PE=1 SV=3
 Gene family
Family typeMembership / link
Orthogroup (gene family)OG0005504 (this species only) · gene tree & orthology

 Pfam domain
Pfam accessionPfam nameDescriptionTypeSource
PF00056
all species →
Ldh_1_Nlactate/malate dehydrogenase, NAD binding domainDomainInterproscan
PF02866
all species →
Ldh_1_Clactate/malate dehydrogenase, alpha/beta C-terminal domainDomainInterproscan

 InterPro
InterPro termTypeDescriptionSource
IPR015955
all species →
Homologous_superfamilyLactate dehydrogenase/glycoside hydrolase, family 4, C-terminalInterproscan
IPR010097
all species →
FamilyMalate dehydrogenase, type 1Interproscan
IPR001252
all species →
Active_siteMalate dehydrogenase, active siteInterproscan
IPR001236
all species →
DomainLactate/malate dehydrogenase, N-terminalInterproscan
IPR036291
all species →
Homologous_superfamilyNAD(P)-binding domain superfamilyInterproscan
IPR022383
all species →
DomainLactate/malate dehydrogenase, C-terminalInterproscan

 PANTHER
PANTHER termDescriptionSource
PTHR11540
all species →
MALATE AND LACTATE DEHYDROGENASEInterproscan

 Gene Ontology
GO termCategoryDescriptionSource
GO:0003824
all species →
Molecular Functioncatalytic activityInterproscan
GO:0016616
all species →
Molecular Functionoxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptorInterproscan
GO:0006099
all species →
Biological Processtricarboxylic acid cycleInterproscan
GO:0030060
all species →
Molecular FunctionL-malate dehydrogenase (NAD+) activityInterproscan
GO:0006108
all species →
Biological Processmalate metabolic processInterproscan
GO:0016615
all species →
Molecular Functionmalate dehydrogenase activityInterproscan
GO:0005737
all species →
Cellular ComponentcytoplasmInterproscan
GO:0005739
all species →
Cellular ComponentmitochondrionInterproscan
GO:0016491
all species →
Molecular Functionoxidoreductase activityInterproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.
 KEGG pathway
No KEGG orthology assignment for amur_s0322.g23.t1.

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of amur_s0322.g23.t1 across 82 RNA-seq samples of Acropora muricata. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

82Samples
71TPM > 0
2Conditions
375.6Max TPM
183.8Mean TPM

By condition

ConditionSamplesTPM > 0 Mean TPMMax TPMMean, relative to max
Polyps 79 71 190.76 375.63
Severed branch 3 0 0.00 0.00

Per sample · hover a bar for the full sample record

Show the sample table (82 samples)
SRA runConditionTissueDevelopmental stage TreatmentStudyTPM
SRR12710851 Polyps Polyps OA 2 day3 not recorded SRP199550 375.63
SRR12710849 Polyps Polyps OA 2 day3 not recorded SRP199550 364.82
SRR12710861 Polyps Polyps OA 2 day9 not recorded SRP199550 364.72
SRR12710850 Polyps Polyps OA 2 day3 not recorded SRP199550 354.96
SRR12710859 Polyps Polyps OA 2 day9 not recorded SRP199550 349.69
SRR12710860 Polyps Polyps OA 2 day9 not recorded SRP199550 335.40
SRR27940227 Polyps Polyps not recorded not recorded SRP199550 334.89
SRR27868193 Polyps Polyps regeneration day24 not recorded SRP199550 294.35
SRR27868196 Polyps Polyps regeneration day21 not recorded SRP199550 287.98
SRR12959232 Polyps Polyps E2 day3 not recorded SRP199550 284.79
SRR12959192 Polyps Polyps E2 day21 not recorded SRP199550 270.64
SRR27868195 Polyps Polyps regeneration day21 not recorded SRP199550 269.45
SRR12786899 Polyps Polyps OA 2 day0 not recorded SRP199550 261.72
SRR12959231 Polyps Polyps E2 day3 not recorded SRP199550 257.36
SRR12786901 Polyps Polyps OA 2 day0 not recorded SRP199550 255.31
SRR12959195 Polyps Polyps E2 day0 not recorded SRP199550 253.67
SRR12959191 Polyps polyps E2 day21 not recorded SRP199550 252.44
SRR12959233 Polyps Polyps E2 day3 not recorded SRP199550 251.07
SRR12786900 Polyps Polyps OA 2 day0 not recorded SRP199550 250.58
SRR12959207 Polyps Polyps E2 day15 not recorded SRP199550 248.46
SRR12959193 Polyps Polyps E2 day21 not recorded SRP199550 247.28
SRR12959219 Polyps Polyps E2 day9 not recorded SRP199550 241.21
SRR27868204 Polyps Polyps regeneration day12 not recorded SRP199550 240.32
SRR27868210 Polyps Polyps regeneration day0 not recorded SRP199550 239.86
SRR27940228 Polyps Polyps not recorded not recorded SRP199550 239.78
SRR27868178 Polyps Polyps regeneration day36 not recorded SRP199550 238.23
SRR12904786 Polyps Polyps not recorded not recorded SRP199550 237.74
SRR27940222 Polyps Polyps not recorded not recorded SRP199550 233.23
SRR27868181 Polyps Polyps regeneration day33 not recorded SRP199550 231.63
SRR12959217 Polyps Polyps E2 day0 not recorded SRP199550 228.24
SRR12959220 Polyps Polyps E2 day9 not recorded SRP199550 226.48
SRR27868158 Polyps Polyps regeneration day6 not recorded SRP199550 221.20
SRR12959218 Polyps Polyps E2 day9 not recorded SRP199550 216.36
SRR27868160 Polyps Polyps regeneration day6 not recorded SRP199550 211.82
SRR27868208 Polyps Polyps regeneration day9 not recorded SRP199550 211.12
SRR27868200 Polyps Polyps regeneration day18 not recorded SRP199550 203.31
SRR27868180 Polyps Polyps regeneration day36 not recorded SRP199550 203.13
SRR12959204 Polyps Polyps E2 day15 not recorded SRP199550 199.35
SRR27868165 Polyps Polyps regeneration day3 not recorded SRP199550 197.96
SRR27868197 Polyps Polyps regeneration day18 not recorded SRP199550 195.94
SRR27868199 Polyps Polyps regeneration day18 not recorded SRP199550 193.99
SRR12959205 Polyps Polyps E2 day15 not recorded SRP199550 190.86
SRR27868185 Polyps Polyps regeneration day30 not recorded SRP199550 188.15
SRR27868207 Polyps Polyps regeneration day9 not recorded SRP199550 188.04
SRR12959206 Polyps Polyps E2 day0 not recorded SRP199550 187.55
SRR27868177 Polyps Polyps regeneration day39 not recorded SRP199550 187.08
SRR27868183 Polyps Polyps regeneration day33 not recorded SRP199550 186.80
SRR27868194 Polyps Polyps regeneration day21 not recorded SRP199550 185.55
SRR27940224 Polyps Polyps not recorded not recorded SRP199550 184.24
SRR27868192 Polyps Polyps regeneration day24 not recorded SRP199550 184.15
SRR27868184 Polyps Polyps regeneration day30 not recorded SRP199550 183.06
SRR12904784 Polyps Polyps not recorded not recorded SRP199550 182.40
SRR27868159 Polyps Polyps regeneration day6 not recorded SRP199550 169.70
SRR27868189 Polyps Polyps regeneration day27 not recorded SRP199550 161.22
SRR27868174 Polyps Polyps regeneration day39 not recorded SRP199550 155.47
SRR27868209 Polyps Polyps regeneration day0 not recorded SRP199550 153.16
SRR27868188 Polyps Polyps regeneration day27 not recorded SRP199550 152.42
SRR12904785 Polyps Polyps not recorded not recorded SRP199550 151.08
SRR27868179 Polyps Polyps regeneration day36 not recorded SRP199550 147.99
SRR27868206 Polyps Polyps regeneration day12 not recorded SRP199550 145.81
SRR27868187 Polyps Polyps regeneration day3 not recorded SRP199550 138.42
SRR27868176 Polyps Polyps regeneration day3 not recorded SRP199550 137.06
SRR27868198 Polyps Polyps regeneration day0 not recorded SRP199550 128.52
SRR27868202 Polyps Polyps regeneration day15 not recorded SRP199550 122.61
SRR27868203 Polyps Polyps regeneration day15 not recorded SRP199550 120.90
SRR27868186 Polyps Polyps regeneration day30 not recorded SRP199550 116.01
SRR27868182 Polyps Polyps regeneration day33 not recorded SRP199550 115.95
SRR27868205 Polyps Polyps regeneration day12 not recorded SRP199550 115.13
SRR27868175 Polyps Polyps regeneration day39 not recorded SRP199550 101.21
SRR27940225 Polyps Polyps not recorded not recorded SRP199550 75.72
SRR27868190 Polyps Polyps regeneration day27 not recorded SRP199550 38.05
SRR12807382 Polyps Polyps OA2 day0 not recorded SRP199550 0.00
SRR12927881 Polyps Polyps E2 day0 not recorded SRP199550 0.00
SRR27868191 Polyps Polyps regeneration day24 not recorded SRP199550 0.00
SRR27868201 Polyps Polyps regeneration day15 not recorded SRP199550 0.00
SRR27940226 Polyps Polyps not recorded not recorded SRP199550 0.00
SRR27940229 Polyps Polyps not recorded not recorded SRP199550 0.00
SRR9613488 Polyps Polyps not recorded not recorded SRP199550 0.00
SRR9613516 Polyps Polyps not recorded not recorded SRP199550 0.00
SRR12995717 Severed branch Severed branch regeneration day0 not recorded SRP199550 0.00
SRR12996627 Severed branch Severed branch regeneration day0 not recorded SRP199550 0.00
SRR12996628 Severed branch Severed branch regeneration High gene expression not recorded SRP199550 0.00

Source: CnidoSite RNA-seq expression matrices (AMURI_TPM, StringTie quantification over 82 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.

Co-expression network

Genes whose expression across the transcriptome samples of Acropora muricata tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

DirectionPartnersMost correlated partnerPCC
Positively correlated35amur_s0473.g6.t10.84989495840503
Negatively correlated14amur_s0022.g29.t1-0.368319541250869

Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Acropora muricata, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

DatasetTissue / stageCellsCell typesThis geneMarker of
AMURI_regenPolyps · regeneration8,72128unmapped

A gene is in viewer when the dataset ships a per-cell expression vector for it; marker only means it is in the dataset’s ranked marker table but no vector was exported, so the atlas cannot draw it; not in this dataset means the dataset’s own gene-ID table does not list it, so no expression claim can be made for that dataset. unmapped is deliberately weaker still: the dataset has no gene-ID table on CnidoSite yet, so nothing is claimed in either direction. Where markers are listed, the numbers are log2 fold change and the percentage of cells of that type in which the gene was detected.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

AnalysisWhat it doesStatus
Primer designDesign PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.template foundopen →
BLASTSearch this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.template foundopen →
Expression heatmapDraw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.readyopen →
Gene family / orthogroupLook this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.open →
Gene set analysisStart a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.open →
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