Genomic Location: sc0000433_pilon:103286...127749
NR annotation: XP_029179380.2, sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1-like isoform X1 [Acropora millepora]
Species Acropora muricata · all data for this species · gene families
| CDS |
| amur_s0433.g12.t1 |
| Transcript |
| amur_s0433.g12.t1 |
| Protein |
| amur_s0433.g12.t1 |
| UniProt accession | Description |
|---|---|
| P0C6B8 | Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 OS=Rattus norvegicus OX=10116 GN=Svep1 PE=1 SV=1 |
| A2AVA0 | Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 OS=Mus musculus OX=10090 GN=Svep1 PE=1 SV=1 |
| A0A1D5NSM8 | Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 OS=Danio rerio OX=7955 GN=svep1 PE=1 SV=1 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0000607 (this species only) · gene tree & orthology |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF00084 all species → | Sushi | Sushi repeat (SCR repeat) | Domain | Interproscan |
| PF00354 all species → | Pentaxin | Pentaxin family | Domain | Interproscan |
| PF00008 all species → | EGF | EGF-like domain | Domain | Interproscan |
| PF07645 all species → | EGF_CA | Calcium-binding EGF domain | Domain | Interproscan |
| PF00431 all species → | CUB | CUB domain | Domain | Interproscan |
| PF00092 all species → | VWA | von Willebrand factor type A domain | Domain | Interproscan |
| PF00754 all species → | F5_F8_type_C | F5/8 type C domain | Domain | Interproscan |
| PF12661 all species → | hEGF | Human growth factor-like EGF | Domain | Interproscan |
| PF07699 all species → | Ephrin_rec_like | Tyrosine-protein kinase ephrin type A/B receptor-like | Domain | Interproscan |
| PF02494 all species → | HYR | HYR domain | Domain | Interproscan |
| PF12662 all species → | cEGF | Complement Clr-like EGF-like | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR000152 all species → | PTM | EGF-type aspartate/asparagine hydroxylation site | Interproscan |
| IPR035976 all species → | Homologous_superfamily | Sushi/SCR/CCP superfamily | Interproscan |
| IPR000436 all species → | Domain | Sushi/SCR/CCP domain | Interproscan |
| IPR003410 all species → | Domain | HYR domain | Interproscan |
| IPR002035 all species → | Domain | von Willebrand factor, type A | Interproscan |
| IPR000742 all species → | Domain | EGF-like domain | Interproscan |
| IPR035914 all species → | Homologous_superfamily | Spermadhesin, CUB domain superfamily | Interproscan |
| IPR001759 all species → | Family | Pentraxin-related | Interproscan |
| IPR018097 all species → | Conserved_site | EGF-like calcium-binding, conserved site | Interproscan |
| IPR013320 all species → | Homologous_superfamily | Concanavalin A-like lectin/glucanase domain superfamily | Interproscan |
| IPR000859 all species → | Domain | CUB domain | Interproscan |
| IPR000421 all species → | Domain | Coagulation factor 5/8 C-terminal domain | Interproscan |
| IPR049883 all species → | Domain | NOTCH1 EGF-like calcium-binding domain | Interproscan |
| IPR036465 all species → | Homologous_superfamily | von Willebrand factor A-like domain superfamily | Interproscan |
| IPR008979 all species → | Homologous_superfamily | Galactose-binding-like domain superfamily | Interproscan |
| IPR013032 all species → | Conserved_site | EGF-like, conserved site | Interproscan |
| IPR003609 all species → | Domain | PAN/Apple domain | Interproscan |
| IPR050350 all species → | Family | Complement & Cell Adhesion Regulators | Interproscan |
| IPR001881 all species → | Domain | EGF-like calcium-binding domain | Interproscan |
| IPR009030 all species → | Homologous_superfamily | Growth factor receptor cysteine-rich domain superfamily | Interproscan |
| IPR011641 all species → | Domain | Tyrosine-protein kinase ephrin type A/B receptor-like | Interproscan |
| IPR006558 all species → | Domain | LamG-like jellyroll fold | Interproscan |
| IPR026823 all species → | Domain | Complement Clr-like EGF domain | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR19325 all species → | COMPLEMENT COMPONENT-RELATED SUSHI DOMAIN-CONTAINING | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0005509 all species → | Molecular Function | calcium ion binding | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K24469 | SVEP1; sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 | - | Domain-containing proteins not elsewhere classified | ko04990 | deepkoala |
Transcript abundance of amur_s0433.g12.t1 across 82 RNA-seq samples of Acropora muricata. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.
| Condition | Samples | TPM > 0 | Mean TPM | Max TPM | Mean, relative to max |
|---|---|---|---|---|---|
| Polyps | 79 | 53 | 1.23 | 27.63 | |
| Severed branch | 3 | 0 | 0.00 | 0.00 |
| SRA run | Condition | Tissue | Developmental stage | Treatment | Study | TPM |
|---|---|---|---|---|---|---|
| SRR27868185 | Polyps | Polyps | regeneration day30 | not recorded | SRP199550 | 27.63 |
| SRR27868183 | Polyps | Polyps | regeneration day33 | not recorded | SRP199550 | 4.68 |
| SRR27868181 | Polyps | Polyps | regeneration day33 | not recorded | SRP199550 | 4.59 |
| SRR27868177 | Polyps | Polyps | regeneration day39 | not recorded | SRP199550 | 4.49 |
| SRR27868190 | Polyps | Polyps | regeneration day27 | not recorded | SRP199550 | 3.47 |
| SRR27868182 | Polyps | Polyps | regeneration day33 | not recorded | SRP199550 | 3.26 |
| SRR27868188 | Polyps | Polyps | regeneration day27 | not recorded | SRP199550 | 2.87 |
| SRR27868203 | Polyps | Polyps | regeneration day15 | not recorded | SRP199550 | 1.93 |
| SRR27868158 | Polyps | Polyps | regeneration day6 | not recorded | SRP199550 | 1.89 |
| SRR27868202 | Polyps | Polyps | regeneration day15 | not recorded | SRP199550 | 1.81 |
| SRR27868197 | Polyps | Polyps | regeneration day18 | not recorded | SRP199550 | 1.77 |
| SRR27868189 | Polyps | Polyps | regeneration day27 | not recorded | SRP199550 | 1.77 |
| SRR27868187 | Polyps | Polyps | regeneration day3 | not recorded | SRP199550 | 1.76 |
| SRR27868174 | Polyps | Polyps | regeneration day39 | not recorded | SRP199550 | 1.65 |
| SRR12959195 | Polyps | Polyps | E2 day0 | not recorded | SRP199550 | 1.65 |
| SRR12959218 | Polyps | Polyps | E2 day9 | not recorded | SRP199550 | 1.63 |
| SRR12959220 | Polyps | Polyps | E2 day9 | not recorded | SRP199550 | 1.59 |
| SRR27868207 | Polyps | Polyps | regeneration day9 | not recorded | SRP199550 | 1.58 |
| SRR12959217 | Polyps | Polyps | E2 day0 | not recorded | SRP199550 | 1.51 |
| SRR27868208 | Polyps | Polyps | regeneration day9 | not recorded | SRP199550 | 1.48 |
| SRR27868206 | Polyps | Polyps | regeneration day12 | not recorded | SRP199550 | 1.43 |
| SRR12959219 | Polyps | Polyps | E2 day9 | not recorded | SRP199550 | 1.34 |
| SRR27868179 | Polyps | Polyps | regeneration day36 | not recorded | SRP199550 | 1.34 |
| SRR12959204 | Polyps | Polyps | E2 day15 | not recorded | SRP199550 | 1.27 |
| SRR27868200 | Polyps | Polyps | regeneration day18 | not recorded | SRP199550 | 1.22 |
| SRR27868176 | Polyps | Polyps | regeneration day3 | not recorded | SRP199550 | 1.20 |
| SRR12959193 | Polyps | Polyps | E2 day21 | not recorded | SRP199550 | 1.16 |
| SRR12959191 | Polyps | polyps | E2 day21 | not recorded | SRP199550 | 1.05 |
| SRR12959231 | Polyps | Polyps | E2 day3 | not recorded | SRP199550 | 0.97 |
| SRR27868194 | Polyps | Polyps | regeneration day21 | not recorded | SRP199550 | 0.95 |
| SRR12904784 | Polyps | Polyps | not recorded | not recorded | SRP199550 | 0.94 |
| SRR27940224 | Polyps | Polyps | not recorded | not recorded | SRP199550 | 0.93 |
| SRR12959192 | Polyps | Polyps | E2 day21 | not recorded | SRP199550 | 0.88 |
| SRR12904785 | Polyps | Polyps | not recorded | not recorded | SRP199550 | 0.88 |
| SRR27868209 | Polyps | Polyps | regeneration day0 | not recorded | SRP199550 | 0.83 |
| SRR12959205 | Polyps | Polyps | E2 day15 | not recorded | SRP199550 | 0.81 |
| SRR27868204 | Polyps | Polyps | regeneration day12 | not recorded | SRP199550 | 0.76 |
| SRR12959233 | Polyps | Polyps | E2 day3 | not recorded | SRP199550 | 0.66 |
| SRR12786899 | Polyps | Polyps | OA 2 day0 | not recorded | SRP199550 | 0.63 |
| SRR27868210 | Polyps | Polyps | regeneration day0 | not recorded | SRP199550 | 0.53 |
| SRR27940228 | Polyps | Polyps | not recorded | not recorded | SRP199550 | 0.53 |
| SRR12904786 | Polyps | Polyps | not recorded | not recorded | SRP199550 | 0.52 |
| SRR12786900 | Polyps | Polyps | OA 2 day0 | not recorded | SRP199550 | 0.48 |
| SRR27868196 | Polyps | Polyps | regeneration day21 | not recorded | SRP199550 | 0.46 |
| SRR12710851 | Polyps | Polyps | OA 2 day3 | not recorded | SRP199550 | 0.44 |
| SRR27868195 | Polyps | Polyps | regeneration day21 | not recorded | SRP199550 | 0.33 |
| SRR27940222 | Polyps | Polyps | not recorded | not recorded | SRP199550 | 0.31 |
| SRR12786901 | Polyps | Polyps | OA 2 day0 | not recorded | SRP199550 | 0.28 |
| SRR12710850 | Polyps | Polyps | OA 2 day3 | not recorded | SRP199550 | 0.25 |
| SRR12710861 | Polyps | Polyps | OA 2 day9 | not recorded | SRP199550 | 0.22 |
| SRR12710860 | Polyps | Polyps | OA 2 day9 | not recorded | SRP199550 | 0.18 |
| SRR12710849 | Polyps | Polyps | OA 2 day3 | not recorded | SRP199550 | 0.12 |
| SRR12710859 | Polyps | Polyps | OA 2 day9 | not recorded | SRP199550 | 0.08 |
| SRR12807382 | Polyps | Polyps | OA2 day0 | not recorded | SRP199550 | 0.00 |
| SRR12927881 | Polyps | Polyps | E2 day0 | not recorded | SRP199550 | 0.00 |
| SRR12959206 | Polyps | Polyps | E2 day0 | not recorded | SRP199550 | 0.00 |
| SRR12959207 | Polyps | Polyps | E2 day15 | not recorded | SRP199550 | 0.00 |
| SRR12959232 | Polyps | Polyps | E2 day3 | not recorded | SRP199550 | 0.00 |
| SRR27868159 | Polyps | Polyps | regeneration day6 | not recorded | SRP199550 | 0.00 |
| SRR27868160 | Polyps | Polyps | regeneration day6 | not recorded | SRP199550 | 0.00 |
| SRR27868165 | Polyps | Polyps | regeneration day3 | not recorded | SRP199550 | 0.00 |
| SRR27868175 | Polyps | Polyps | regeneration day39 | not recorded | SRP199550 | 0.00 |
| SRR27868178 | Polyps | Polyps | regeneration day36 | not recorded | SRP199550 | 0.00 |
| SRR27868180 | Polyps | Polyps | regeneration day36 | not recorded | SRP199550 | 0.00 |
| SRR27868184 | Polyps | Polyps | regeneration day30 | not recorded | SRP199550 | 0.00 |
| SRR27868186 | Polyps | Polyps | regeneration day30 | not recorded | SRP199550 | 0.00 |
| SRR27868191 | Polyps | Polyps | regeneration day24 | not recorded | SRP199550 | 0.00 |
| SRR27868192 | Polyps | Polyps | regeneration day24 | not recorded | SRP199550 | 0.00 |
| SRR27868193 | Polyps | Polyps | regeneration day24 | not recorded | SRP199550 | 0.00 |
| SRR27868198 | Polyps | Polyps | regeneration day0 | not recorded | SRP199550 | 0.00 |
| SRR27868199 | Polyps | Polyps | regeneration day18 | not recorded | SRP199550 | 0.00 |
| SRR27868201 | Polyps | Polyps | regeneration day15 | not recorded | SRP199550 | 0.00 |
| SRR27868205 | Polyps | Polyps | regeneration day12 | not recorded | SRP199550 | 0.00 |
| SRR27940225 | Polyps | Polyps | not recorded | not recorded | SRP199550 | 0.00 |
| SRR27940226 | Polyps | Polyps | not recorded | not recorded | SRP199550 | 0.00 |
| SRR27940227 | Polyps | Polyps | not recorded | not recorded | SRP199550 | 0.00 |
| SRR27940229 | Polyps | Polyps | not recorded | not recorded | SRP199550 | 0.00 |
| SRR9613488 | Polyps | Polyps | not recorded | not recorded | SRP199550 | 0.00 |
| SRR9613516 | Polyps | Polyps | not recorded | not recorded | SRP199550 | 0.00 |
| SRR12995717 | Severed branch | Severed branch | regeneration day0 | not recorded | SRP199550 | 0.00 |
| SRR12996627 | Severed branch | Severed branch | regeneration day0 | not recorded | SRP199550 | 0.00 |
| SRR12996628 | Severed branch | Severed branch | regeneration High gene expression | not recorded | SRP199550 | 0.00 |
Source: CnidoSite RNA-seq expression matrices (AMURI_TPM,
StringTie quantification over 82 runs), joined to SRA sample
metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped
by the descriptor carried in the expression matrix itself.
Genes whose expression across the transcriptome samples of Acropora muricata tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.
| Direction | Partners | Most correlated partner | PCC |
|---|---|---|---|
| Positively correlated | 44 | amur_s6584.g1.t1 | 0.945634165992961 |
| Negatively correlated | 10 | amur_s0052.g58.t1 | -0.25310353068211 |
Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list.
Whether this gene can be visualised in the single-cell atlases of Acropora muricata, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.
| Dataset | Tissue / stage | Cells | Cell types | This gene | Marker of |
|---|---|---|---|---|---|
| AMURI_regen | Polyps · regeneration | 8,721 | 28 | unmapped | – |
A gene is in viewer when the dataset ships a per-cell expression vector for it; marker only means it is in the dataset’s ranked marker table but no vector was exported, so the atlas cannot draw it; not in this dataset means the dataset’s own gene-ID table does not list it, so no expression claim can be made for that dataset. unmapped is deliberately weaker still: the dataset has no gene-ID table on CnidoSite yet, so nothing is claimed in either direction. Where markers are listed, the numbers are log2 fold change and the percentage of cells of that type in which the gene was detected.
Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.
No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.
Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.
| Analysis | What it does | Status | |
|---|---|---|---|
| Primer design | Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed. | template found | open → |
| BLAST | Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start. | template found | open → |
| Expression heatmap | Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it. | ready | open → |
| Gene family / orthogroup | Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue. | open → | |
| Gene set analysis | Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it. | open → |