Genomic Location: sc0000132_pilon:104096...122698
NR annotation: XP_015772278.1, PREDICTED: rap guanine nucleotide exchange factor 4-like [Acropora digitifera]
| CDS | |||||
| anas_s0132.g12.t1 | |||||
| Transcript |
| anas_s0132.g12.t1 |
| Protein |
| anas_s0132.g12.t1 |
| Uniprot term | Description |
|---|---|
| Q8WZA2 | Rap guanine nucleotide exchange factor 4 OS=Homo sapiens OX=9606 GN=RAPGEF4 PE=1 SV=1 |
| Q9EQZ6 | Rap guanine nucleotide exchange factor 4 OS=Mus musculus OX=10090 GN=Rapgef4 PE=1 SV=1 |
| O95398 | Rap guanine nucleotide exchange factor 3 OS=Homo sapiens OX=9606 GN=RAPGEF3 PE=1 SV=6 |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF00617 | RasGEF | RasGEF domain | Family | Interproscan |
| PF00027 | cNMP_binding | Cyclic nucleotide-binding domain | Domain | Interproscan |
| PF00618 | RasGEF_N | RasGEF N-terminal motif | Domain | Interproscan |
| PF00610 | DEP | Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR000651 | Domain | Ras-like guanine nucleotide exchange factor, N-terminal | Interproscan |
| IPR000595 | Domain | Cyclic nucleotide-binding domain | Interproscan |
| IPR029071 | Homologous_superfamily | Ubiquitin-like domain superfamily | Interproscan |
| IPR018490 | Homologous_superfamily | Cyclic nucleotide-binding domain superfamily | Interproscan |
| IPR014710 | Homologous_superfamily | RmlC-like jelly roll fold | Interproscan |
| IPR001895 | Domain | Ras guanine-nucleotide exchange factors catalytic domain | Interproscan |
| IPR036388 | Homologous_superfamily | Winged helix-like DNA-binding domain superfamily | Interproscan |
| IPR036390 | Homologous_superfamily | Winged helix DNA-binding domain superfamily | Interproscan |
| IPR036964 | Homologous_superfamily | Ras guanine-nucleotide exchange factor, catalytic domain superfamily | Interproscan |
| IPR008937 | Family | Ras-like guanine nucleotide exchange factor | Interproscan |
| IPR000591 | Domain | DEP domain | Interproscan |
| IPR023578 | Homologous_superfamily | Ras guanine nucleotide exchange factor domain superfamily | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR23113 | GUANINE NUCLEOTIDE EXCHANGE FACTOR | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0005085 | Molecular Function | guanyl-nucleotide exchange factor activity | Interproscan |
| GO:0007264 | Biological Process | small GTPase-mediated signal transduction | Interproscan |
| GO:0005886 | Cellular Component | plasma membrane | Interproscan |
| GO:0007265 | Biological Process | Ras protein signal transduction | Interproscan |
| GO:0043547 | Biological Process | positive regulation of GTPase activity | Interproscan |
| GO:0035556 | Biological Process | intracellular signal transduction | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K04351 | RAPGEF4, EPAC2; Rap guanine nucleotide exchange factor 4 | - | Membrane trafficking | ko04131 | deepkoala |