Gene detail

Detailed information of asel_s0010.g34.t2 in Acropora selago

Genomic Location: sc0000010_pilon:762374...775051
NR annotation: XP_015760364.1, PREDICTED: speckle-type POZ protein B-like [Acropora digitifera]
Species Acropora selago · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

Transcript

asel_s0010.g34.t2

CTTATTTTCGTGCGCACAAACAAATGGCGAAAACCGCGCAACATTCCCGGATACAACAAAAGAAGACTTGAAACTAGTCTGGAAGTGGTCTCTGAAAAAAGGTTCGTGAGTTGGACAGGAAAAAAGTACACGCTCAGAGGAGCTCAGAGTTGTTCATCTGGTGGCTACAGCAAGACTCTCCACCCTGGCTGCAGTATCTTGTTGCGAGTCATCTAAGATGTCTTCCTCATCGCCAGTGGCGGAGAACTGGTGTTACACACAAATAAAGGTCATCAAGTTCTCATACATGTGGACTATAAACAACTTCAGCTTCTGTCGTGAGGAAATGGGAGAAACTCTTAAGAGTTCCACATTTTCTGCTGGTGCTAATGATAAGATGAAATGGTGTTTAAGGGTAAATCCACGTGGATTGGATGAAGAAAGCAAAGATTATCTTTCGCTGTATCTTCTATTGCTTGCTTGTAACAAAAGTGAAGTCCGCGCAAAGTTCAAGTTTTCAATTCTCAATGCCAACAGGGAGGAAACAAAAGCTATGGAGAGCCAAAGAGCATACAGATTTGTTCAAGGTAAAGACTGGGGATTCAAAAAGTTCATAAGAAGAGACTTTCTAATGGATGAAGCTAACGGCTTACTACCCAACGACACGCTTACGCTATTTTGTGAGGTCAGTGTGGAAGGCGACTCTGTGAATCTTTCTGGTTCATCTCATACTGCAGCTCTCAAAGTACCAGAGTGCAGACTATCAAAACATATGGGATCACTTTTAGACTCTGGGACATTCAGTGACGTCACGTTATGTACACGTGGTAGAGAATTTAAAGCCCACAAAGCTGTACTGGCGGCACGCTCCCCTGTATTTGGGGCCATGTTTGAACATGAAATGGAAGAAAGCAGACGAGGTCGTGTGGAAATTAGTGACATTGATCCTGACGTTTTTCATGAGATGTTAAAATTTATTTACACTGGGAGTACTCCACAGCTGCAAGGAATGGCTGATGATCTCTTGGCGGCAGCAGATAAGATGTTAAAATTTATTTACACTGGGAGTACTCCACAGCTGCAAGGAATGGCTGATGATCTATTGGCGGCAGCAGATAAGTATGACCTTGACAGACTAAAAGTTATGTGTGAGGAAGCATTGTGCTCAAATTTAACGGTAGACAATGTTTGTGACGTGCTCATATTAGCTGACATGCACAGTGCTACACAGCTGAAGGCACAAGCTCTGGACTTCATCAACAGTCGTGCAACAGATGTGATGGAATCAAATGGATGGAAGACATTAGTCAGAGATCACACACATCTTATTGCAGAGGTTTTCAAGGCATTCCTAGCTTCAACACAAACACCTTTAGTAGGCCCACCCAGAAAAAGACAGAAGACATCGTAAGCTGGATAAGGGATGTATACATTGTTGTAAGAAAAAAATTATCAAAATATTATATAAAATGTTTCTCCTGGGAACGATCAGATTTTTTTTTCAGCTGCAGGTCTTAAAGACAAAATTTCTAGTTAAAAATTGAATTTTTTTTGTTTATTGAGGATTAAAATTTGGTCCTCAATAATGTCTGTCGGCTGGTTTTCCACACAAAGTTACTCCCTTTTTATTTTAAAGTCTTCACTTTCTGCACCCTTTGCTTTGTTTTCTTGGCTTTATTTTCTACCTTATCCTATCTGTACATGAACCGCTCTCATTCTATGTGTACATTTCTATGCATTCATTGTGTATATTCCTCCCCTCTGTGCATTCATTCTCGATCTTTCTTTCTTTTCTTTAACTTAATTGAAACTTGTCACCAAGAGAAAAAAACTGACTGTTCCCAGGTTTTGTAAAAAATAAATGATTGTTCTTGAATATAAAGCTATGTATAATATTTGAGTAAAAGTGTTGGCTGATTTCTTTACTGACAAGGAGTCACTTGGTGACTCAATATTCAACTTCAACAAATGCAGGAACACTTGAATGATGGCTATTCTAGTAAGAGCTGTTGTGCAAAATGATTTCCATTCTGTTAGTTACATTTGAGAACTTTGTACTTGACATAAAACTGTACATGACATTGCACAACACCAACAACTTGGGCTGGCTCAAGTTTACTCTTTGTAGACTGACAAAACATAAGAAAAATTTCACCGCACTTAGTGAGGTGAATAATAAGGTGTCATTTCCCGTGATTTTATTCCTGATTGAGTTCAATCTTACATTGTCCAAGACTGACCTGCAGCCcttgcccgcgttgctctaagtatggttagcgctaaccaatgtaactaccatagacacgtttagcttttggtaccttttaaccattggttagtgcttaccatgctttgagcaaccggccagtctggtcagtaaTAATTTTGGTATATTGTCACCGTGGTTGTTTTGGGAATTGAAAGGCCTAATTAAGGTGATGGTTGGTTGGTAATGGTCAAAAATAACTTTTTGTTTTCACCCACCAGAGAATTAATTATTCTGCCTTGTTGTCATACTTTGTGAAATTCAAGCTGGACTTGATTTAAACTATTCATCATAATTAGTACAAAGTAATACTGAACTGCAATATTATTTCAAGCTCAAAGCATCACTTAAGGCACGGCAGGTTTCTTTCAATAGTTATGGCTTGTAGGGCAATATTATAGACTGGTTATACTCAAGTGAAGTAAATTACTATGTATTGAAATCAAATTGGAAAGAGGCAACCACTTGGCCAGTGGCAAATATTGATAGAGTTCAGGTCGAAATCAGAGATGACAAAGTAACACAGTTCATGGTCCAAACTGTGCAAATAGAAAATAATTATTGATGTTTTGGCCGCTGGCTATTGCCTCCTCCCCGCAAAATAGTTCTATAATTCCTGAGATAAACATGAGCATACCTTCCCCAAAAATTTACAGACAGCTCTTTGCTTATTGTATGTGTGAGGGGCACCAATATTTGTGTAAAGTGTGCTCACTTGGTTCCCCTGTGCAGGGAGAACTGTTTCTGGCCATTTGCGATTCTTAAGAGGCAATGTTGTCGTGCATTTGCCATTTTGTAAATAAAGTGTTGTTGAATCA

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q0IHH9	Speckle-type POZ protein B OS=Xenopus laevis OX=8355 GN=spop-b PE=2 SV=1
Q7ZX06	Speckle-type POZ protein A OS=Xenopus laevis OX=8355 GN=spop-a PE=2 SV=1
Q6P8B3	Speckle-type POZ protein OS=Xenopus tropicalis OX=8364 GN=spop PE=2 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0006950 (this species only) · gene tree & orthology
Transcription factor family	ZBTB · all TF in this species
Ubiquitin family	E3\|E3 adaptor Cullin RING\|BTB · all ubiquitin genes in this species

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF00651 all species →	BTB	BTB/POZ domain	Domain	Interproscan
PF00917 all species →	MATH	MATH domain	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR011333 all species →	Homologous_superfamily	SKP1/BTB/POZ domain superfamily	Interproscan
IPR002083 all species →	Domain	MATH/TRAF domain	Interproscan
IPR000210 all species →	Domain	BTB/POZ domain	Interproscan
IPR008974 all species →	Homologous_superfamily	TRAF-like	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR24413 all species →	SPECKLE-TYPE POZ PROTEIN	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0005515 all species →	Molecular Function	protein binding	Interproscan
GO:0005737 all species →	Cellular Component	cytoplasm	Interproscan
GO:0030162 all species →	Biological Process	regulation of proteolysis	Interproscan
GO:0031625 all species →	Molecular Function	ubiquitin protein ligase binding	Interproscan
GO:0043161 all species →	Biological Process	proteasome-mediated ubiquitin-dependent protein catabolic process	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K10523	SPOP; speckle-type POZ protein	-	Ubiquitin system	ko04121	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of asel_s0010.g34.t2 across 24 RNA-seq samples of Acropora selago. This gene has no row in the species' RNA-seq expression matrix, so every value below is shown as zero — the matrix simply does not cover this transcript. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

24Samples

0TPM > 0

1Conditions

0.0Max TPM

0.0Mean TPM

By condition

Condition	Samples	TPM > 0	Mean TPM	Max TPM	Mean, relative to max
coral larvae	24	0	0.00	0.00

Per sample · hover a bar for the full sample record

Show the sample table (24 samples)

SRA run	Condition	Tissue	Developmental stage	Treatment	Study
SRR14308004	coral larvae	coral larvae	not recorded	not recorded	SRP315987
SRR14308005	coral larvae	coral larvae	not recorded	not recorded	SRP315987
SRR14308006	coral larvae	coral larvae	not recorded	not recorded	SRP315987
SRR14308007	coral larvae	coral larvae	not recorded	not recorded	SRP315987
SRR14308008	coral larvae	coral larvae	not recorded	not recorded	SRP315987
SRR14308009	coral larvae	coral larvae	not recorded	not recorded	SRP315987
SRR14308010	coral larvae	coral larvae	not recorded	not recorded	SRP315987
SRR14308011	coral larvae	coral larvae	not recorded	not recorded	SRP315987
SRR14308012	coral larvae	coral larvae	not recorded	not recorded	SRP315987
SRR14308013	coral larvae	coral larvae	not recorded	not recorded	SRP315987
SRR14308014	coral larvae	coral larvae	not recorded	not recorded	SRP315987
SRR14308015	coral larvae	coral larvae	not recorded	not recorded	SRP315987
SRR14308016	coral larvae	coral larvae	not recorded	not recorded	SRP315987
SRR14308017	coral larvae	coral larvae	not recorded	not recorded	SRP315987
SRR14308018	coral larvae	coral larvae	not recorded	not recorded	SRP315987
SRR14308019	coral larvae	coral larvae	not recorded	not recorded	SRP315987
SRR14308020	coral larvae	coral larvae	not recorded	not recorded	SRP315987
SRR14308021	coral larvae	coral larvae	not recorded	not recorded	SRP315987
SRR14308022	coral larvae	coral larvae	not recorded	not recorded	SRP315987
SRR14308023	coral larvae	coral larvae	not recorded	not recorded	SRP315987
SRR14308024	coral larvae	coral larvae	not recorded	not recorded	SRP315987
SRR14308025	coral larvae	coral larvae	not recorded	not recorded	SRP315987
SRR14308026	coral larvae	coral larvae	not recorded	not recorded	SRP315987
SRR14308027	coral larvae	coral larvae	not recorded	not recorded	SRP315987

Source: CnidoSite RNA-seq expression matrices (ASELA_TPM, StringTie quantification over 24 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.

Co-expression network

Genes whose expression across the transcriptome samples of Acropora selago tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

Direction	Partners	Most correlated partner	PCC
Positively correlated	0	not in this network	-
Negatively correlated	0	not in this network	-

This gene has no edge at all in the Acropora selago network, in either direction — it is not one of the genes the network was built from (the network covers genes with enough expression variation across the transcriptome samples). The counts above are a property of the network, not a failed lookup.

Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Acropora selago, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

DNA methylation (bisulphite samples)

Sample	Methylation profile
Coral_Fragment_Parent	open
Larval_Pool_Offspring	open

The DNA Methylation page locates this gene by scanning the bisulphite table, which holds one row per cytosine. For the largest datasets that scan takes a while to return; it does not mean the link is broken.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

Analysis	What it does	Status
Primer design	Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.	template found	open →
BLAST	Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.	template found	open →
Expression heatmap	Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.	no expression matrix	–
Gene family / orthogroup	Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.		open →
Gene set analysis	Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.		open →