Genomic Location: sc0000011_pilon:1137265...1138204
NR annotation: XP_029208328.2, nicotinate-nucleotide pyrophosphorylase [carboxylating]-like [Acropora millepora]
Species Acropora selago · all data for this species · gene families
| CDS |
| asel_s0011.g86.t1 |
| Transcript |
| asel_s0011.g86.t1 |
| Protein |
| asel_s0011.g86.t1 |
| UniProt accession | Description |
|---|---|
| A7SG73 | Nicotinate-nucleotide pyrophosphorylase [carboxylating] (Fragment) OS=Nematostella vectensis OX=45351 GN=qprt PE=3 SV=1 |
| Q3T063 | Nicotinate-nucleotide pyrophosphorylase [carboxylating] OS=Bos taurus OX=9913 GN=QPRT PE=2 SV=1 |
| I3LK75 | Nicotinate-nucleotide pyrophosphorylase [carboxylating] OS=Sus scrofa OX=9823 GN=QPRT PE=1 SV=2 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0009539 (this species only) · gene tree & orthology |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF01729 all species → | QRPTase_C | Quinolinate phosphoribosyl transferase, C-terminal domain | Domain | Interproscan |
| PF02749 all species → | QRPTase_N | Quinolinate phosphoribosyl transferase, N-terminal domain | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR004393 all species → | Family | Nicotinate-nucleotide pyrophosphorylase | Interproscan |
| IPR002638 all species → | Domain | Quinolinate phosphoribosyl transferase, C-terminal | Interproscan |
| IPR027277 all species → | Family | Nicotinate-nucleotide pyrophosphorylase/Putative pyrophosphorylase ModD | Interproscan |
| IPR013785 all species → | Homologous_superfamily | Aldolase-type TIM barrel | Interproscan |
| IPR022412 all species → | Domain | Quinolinate phosphoribosyl transferase, N-terminal | Interproscan |
| IPR037128 all species → | Homologous_superfamily | Quinolinate phosphoribosyl transferase, N-terminal domain superfamily | Interproscan |
| IPR036068 all species → | Homologous_superfamily | Nicotinate phosphoribosyltransferase-like, C-terminal | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR32179 all species → | NICOTINATE-NUCLEOTIDE PYROPHOSPHORYLASE [CARBOXYLATING] | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0004514 all species → | Molecular Function | nicotinate-nucleotide diphosphorylase (carboxylating) activity | Interproscan |
| GO:0009435 all species → | Biological Process | NAD biosynthetic process | Interproscan |
| GO:0005737 all species → | Cellular Component | cytoplasm | Interproscan |
| GO:0034213 all species → | Biological Process | quinolinate catabolic process | Interproscan |
| GO:0016763 all species → | Molecular Function | pentosyltransferase activity | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K00767 | nadC, QPRT; nicotinate-nucleotide pyrophosphorylase (carboxylating) | EC:2.4.2.19 | Nicotinate and nicotinamide metabolism | ko00760 | deepkoala |
Transcript abundance of asel_s0011.g86.t1 across 24 RNA-seq samples of Acropora selago. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.
| Condition | Samples | TPM > 0 | Mean TPM | Max TPM | Mean, relative to max |
|---|---|---|---|---|---|
| coral larvae | 24 | 24 | 34.86 | 54.77 |
| SRA run | Condition | Tissue | Developmental stage | Treatment | Study | TPM |
|---|---|---|---|---|---|---|
| SRR14308008 | coral larvae | coral larvae | not recorded | not recorded | SRP315987 | 54.77 |
| SRR14308012 | coral larvae | coral larvae | not recorded | not recorded | SRP315987 | 45.66 |
| SRR14308024 | coral larvae | coral larvae | not recorded | not recorded | SRP315987 | 44.38 |
| SRR14308027 | coral larvae | coral larvae | not recorded | not recorded | SRP315987 | 44.03 |
| SRR14308011 | coral larvae | coral larvae | not recorded | not recorded | SRP315987 | 41.64 |
| SRR14308004 | coral larvae | coral larvae | not recorded | not recorded | SRP315987 | 41.56 |
| SRR14308015 | coral larvae | coral larvae | not recorded | not recorded | SRP315987 | 38.76 |
| SRR14308022 | coral larvae | coral larvae | not recorded | not recorded | SRP315987 | 36.87 |
| SRR14308017 | coral larvae | coral larvae | not recorded | not recorded | SRP315987 | 35.99 |
| SRR14308007 | coral larvae | coral larvae | not recorded | not recorded | SRP315987 | 34.69 |
| SRR14308016 | coral larvae | coral larvae | not recorded | not recorded | SRP315987 | 34.15 |
| SRR14308025 | coral larvae | coral larvae | not recorded | not recorded | SRP315987 | 34.05 |
| SRR14308013 | coral larvae | coral larvae | not recorded | not recorded | SRP315987 | 33.90 |
| SRR14308026 | coral larvae | coral larvae | not recorded | not recorded | SRP315987 | 33.75 |
| SRR14308018 | coral larvae | coral larvae | not recorded | not recorded | SRP315987 | 32.80 |
| SRR14308010 | coral larvae | coral larvae | not recorded | not recorded | SRP315987 | 32.62 |
| SRR14308021 | coral larvae | coral larvae | not recorded | not recorded | SRP315987 | 32.18 |
| SRR14308019 | coral larvae | coral larvae | not recorded | not recorded | SRP315987 | 31.55 |
| SRR14308006 | coral larvae | coral larvae | not recorded | not recorded | SRP315987 | 31.21 |
| SRR14308014 | coral larvae | coral larvae | not recorded | not recorded | SRP315987 | 28.65 |
| SRR14308023 | coral larvae | coral larvae | not recorded | not recorded | SRP315987 | 27.94 |
| SRR14308009 | coral larvae | coral larvae | not recorded | not recorded | SRP315987 | 23.78 |
| SRR14308020 | coral larvae | coral larvae | not recorded | not recorded | SRP315987 | 22.76 |
| SRR14308005 | coral larvae | coral larvae | not recorded | not recorded | SRP315987 | 18.96 |
Source: CnidoSite RNA-seq expression matrices (ASELA_TPM,
StringTie quantification over 24 runs), joined to SRA sample
metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped
by the descriptor carried in the expression matrix itself.
Genes whose expression across the transcriptome samples of Acropora selago tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.
| Direction | Partners | Most correlated partner | PCC |
|---|---|---|---|
| Positively correlated | 13 | asel_s0020.g31.t1 | 0.891817538356561 |
| Negatively correlated | 7 | asel_s0024.g3.t1 | -0.796751125507139 |
Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list.
Whether this gene can be visualised in the single-cell atlases of Acropora selago, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.
No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.
Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.
| Sample | Methylation profile |
|---|---|
| Coral_Fragment_Parent | open |
| Larval_Pool_Offspring | open |
The DNA Methylation page locates this gene by scanning the bisulphite table, which holds one row per cytosine. For the largest datasets that scan takes a while to return; it does not mean the link is broken.
Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.
| Analysis | What it does | Status | |
|---|---|---|---|
| Primer design | Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed. | template found | open → |
| BLAST | Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start. | template found | open → |
| Expression heatmap | Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it. | ready | open → |
| Gene family / orthogroup | Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue. | open → | |
| Gene set analysis | Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it. | open → |
