Genomic Location: sc0000046_pilon:1037309...1063605
NR annotation: XP_044184195.1, LOW QUALITY PROTEIN: AP-2 complex subunit alpha-2-like [Acropora millepora]
Species Acropora selago · all data for this species · gene families
| CDS |
| asel_s0046.g63.t2 |
| Transcript |
| asel_s0046.g63.t2 |
| Protein |
| asel_s0046.g63.t2 |
| UniProt accession | Description |
|---|---|
| Q0VCK5 | AP-2 complex subunit alpha-2 OS=Bos taurus OX=9913 GN=AP2A2 PE=1 SV=1 |
| P18484 | AP-2 complex subunit alpha-2 OS=Rattus norvegicus OX=10116 GN=Ap2a2 PE=1 SV=3 |
| P17427 | AP-2 complex subunit alpha-2 OS=Mus musculus OX=10090 GN=Ap2a2 PE=1 SV=2 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0003616 (this species only) · gene tree & orthology |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF01602 all species → | Adaptin_N | Adaptin N terminal region | Repeat | Interproscan |
| PF02883 all species → | Alpha_adaptinC2 | Adaptin C-terminal domain | Domain | Interproscan |
| PF02296 all species → | Alpha_adaptin_C | Alpha adaptin AP2, C-terminal domain | Family | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR011989 all species → | Homologous_superfamily | Armadillo-like helical | Interproscan |
| IPR002553 all species → | Domain | Clathrin/coatomer adaptor, adaptin-like, N-terminal | Interproscan |
| IPR016024 all species → | Homologous_superfamily | Armadillo-type fold | Interproscan |
| IPR008152 all species → | Domain | Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain | Interproscan |
| IPR012295 all species → | Homologous_superfamily | TBP domain superfamily | Interproscan |
| IPR050840 all species → | Family | Adaptor Complexes Large Subunit | Interproscan |
| IPR013041 all species → | Homologous_superfamily | Clathrin adaptor, appendage, Ig-like subdomain superfamily | Interproscan |
| IPR003164 all species → | Domain | Clathrin adaptor, alpha-adaptin, appendage, C-terminal subdomain | Interproscan |
| IPR009028 all species → | Homologous_superfamily | Coatomer/calthrin adaptor appendage, C-terminal subdomain | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR22780 all species → | ADAPTIN, ALPHA/GAMMA/EPSILON | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0006886 all species → | Biological Process | intracellular protein transport | Interproscan |
| GO:0016192 all species → | Biological Process | vesicle-mediated transport | Interproscan |
| GO:0030117 all species → | Cellular Component | membrane coat | Interproscan |
| GO:0030122 all species → | Cellular Component | AP-2 adaptor complex | Interproscan |
| GO:0035615 all species → | Molecular Function | clathrin adaptor activity | Interproscan |
| GO:0072583 all species → | Biological Process | clathrin-dependent endocytosis | Interproscan |
| GO:0140312 all species → | Molecular Function | cargo adaptor activity | Interproscan |
| GO:0030131 all species → | Cellular Component | clathrin adaptor complex | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K11824 | AP2A; AP-2 complex subunit alpha | - | Exosome | ko04147 | deepkoala |
Transcript abundance of asel_s0046.g63.t2 across 24 RNA-seq samples of Acropora selago. This gene has no row in the species' RNA-seq expression matrix, so every value below is shown as zero — the matrix simply does not cover this transcript. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.
| Condition | Samples | TPM > 0 | Mean TPM | Max TPM | Mean, relative to max |
|---|---|---|---|---|---|
| coral larvae | 24 | 0 | 0.00 | 0.00 |
| SRA run | Condition | Tissue | Developmental stage | Treatment | Study | TPM |
|---|---|---|---|---|---|---|
| SRR14308004 | coral larvae | coral larvae | not recorded | not recorded | SRP315987 | 0.00 |
| SRR14308005 | coral larvae | coral larvae | not recorded | not recorded | SRP315987 | 0.00 |
| SRR14308006 | coral larvae | coral larvae | not recorded | not recorded | SRP315987 | 0.00 |
| SRR14308007 | coral larvae | coral larvae | not recorded | not recorded | SRP315987 | 0.00 |
| SRR14308008 | coral larvae | coral larvae | not recorded | not recorded | SRP315987 | 0.00 |
| SRR14308009 | coral larvae | coral larvae | not recorded | not recorded | SRP315987 | 0.00 |
| SRR14308010 | coral larvae | coral larvae | not recorded | not recorded | SRP315987 | 0.00 |
| SRR14308011 | coral larvae | coral larvae | not recorded | not recorded | SRP315987 | 0.00 |
| SRR14308012 | coral larvae | coral larvae | not recorded | not recorded | SRP315987 | 0.00 |
| SRR14308013 | coral larvae | coral larvae | not recorded | not recorded | SRP315987 | 0.00 |
| SRR14308014 | coral larvae | coral larvae | not recorded | not recorded | SRP315987 | 0.00 |
| SRR14308015 | coral larvae | coral larvae | not recorded | not recorded | SRP315987 | 0.00 |
| SRR14308016 | coral larvae | coral larvae | not recorded | not recorded | SRP315987 | 0.00 |
| SRR14308017 | coral larvae | coral larvae | not recorded | not recorded | SRP315987 | 0.00 |
| SRR14308018 | coral larvae | coral larvae | not recorded | not recorded | SRP315987 | 0.00 |
| SRR14308019 | coral larvae | coral larvae | not recorded | not recorded | SRP315987 | 0.00 |
| SRR14308020 | coral larvae | coral larvae | not recorded | not recorded | SRP315987 | 0.00 |
| SRR14308021 | coral larvae | coral larvae | not recorded | not recorded | SRP315987 | 0.00 |
| SRR14308022 | coral larvae | coral larvae | not recorded | not recorded | SRP315987 | 0.00 |
| SRR14308023 | coral larvae | coral larvae | not recorded | not recorded | SRP315987 | 0.00 |
| SRR14308024 | coral larvae | coral larvae | not recorded | not recorded | SRP315987 | 0.00 |
| SRR14308025 | coral larvae | coral larvae | not recorded | not recorded | SRP315987 | 0.00 |
| SRR14308026 | coral larvae | coral larvae | not recorded | not recorded | SRP315987 | 0.00 |
| SRR14308027 | coral larvae | coral larvae | not recorded | not recorded | SRP315987 | 0.00 |
Source: CnidoSite RNA-seq expression matrices (ASELA_TPM,
StringTie quantification over 24 runs), joined to SRA sample
metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped
by the descriptor carried in the expression matrix itself.
Genes whose expression across the transcriptome samples of Acropora selago tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.
| Direction | Partners | Most correlated partner | PCC |
|---|---|---|---|
| Positively correlated | 0 | not in this network | - |
| Negatively correlated | 0 | not in this network | - |
This gene has no edge at all in the Acropora selago network, in either direction — it is not one of the genes the network was built from (the network covers genes with enough expression variation across the transcriptome samples). The counts above are a property of the network, not a failed lookup.
Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list.
Whether this gene can be visualised in the single-cell atlases of Acropora selago, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.
No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.
Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.
| Sample | Methylation profile |
|---|---|
| Coral_Fragment_Parent | open |
| Larval_Pool_Offspring | open |
The DNA Methylation page locates this gene by scanning the bisulphite table, which holds one row per cytosine. For the largest datasets that scan takes a while to return; it does not mean the link is broken.
Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.
| Analysis | What it does | Status | |
|---|---|---|---|
| Primer design | Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed. | template found | open → |
| BLAST | Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start. | template found | open → |
| Expression heatmap | Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it. | no expression matrix | – |
| Gene family / orthogroup | Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue. | open → | |
| Gene set analysis | Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it. | open → |