Genomic Location: sc0000067_pilon:597689...635889
NR annotation: XP_029194535.2, rho-associated protein kinase 2-like isoform X2 [Acropora millepora]
Species Acropora selago · all data for this species · gene families
| CDS |
| asel_s0067.g48.t2 |
| Transcript |
| asel_s0067.g48.t2 |
| Protein |
| asel_s0067.g48.t2 |
| UniProt accession | Description |
|---|---|
| O75116 | Rho-associated protein kinase 2 OS=Homo sapiens OX=9606 GN=ROCK2 PE=1 SV=4 |
| Q62868 | Rho-associated protein kinase 2 OS=Rattus norvegicus OX=10116 GN=Rock2 PE=1 SV=2 |
| Q28021 | Rho-associated protein kinase 2 OS=Bos taurus OX=9913 GN=ROCK2 PE=1 SV=1 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0002746 (this species only) · gene tree & orthology |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF08912 all species → | Rho_Binding | Rho Binding | Coiled-coil | Interproscan |
| PF00069 all species → | Pkinase | Protein kinase domain | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR008271 all species → | Active_site | Serine/threonine-protein kinase, active site | Interproscan |
| IPR000961 all species → | Domain | AGC-kinase, C-terminal | Interproscan |
| IPR000719 all species → | Domain | Protein kinase domain | Interproscan |
| IPR015008 all species → | Domain | ROCK, Rho binding domain | Interproscan |
| IPR011009 all species → | Homologous_superfamily | Protein kinase-like domain superfamily | Interproscan |
| IPR017441 all species → | Binding_site | Protein kinase, ATP binding site | Interproscan |
| IPR011993 all species → | Homologous_superfamily | PH-like domain superfamily | Interproscan |
| IPR046349 all species → | Homologous_superfamily | C1-like domain superfamily | Interproscan |
| IPR050839 all species → | Family | Rho-associated Serine/Threonine Kinase | Interproscan |
| IPR002219 all species → | Domain | Protein kinase C-like, phorbol ester/diacylglycerol-binding domain | Interproscan |
| IPR001849 all species → | Domain | Pleckstrin homology domain | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR22988 all species → | MYOTONIC DYSTROPHY S/T KINASE-RELATED | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0004672 all species → | Molecular Function | protein kinase activity | Interproscan |
| GO:0006468 all species → | Biological Process | protein phosphorylation | Interproscan |
| GO:0004674 all species → | Molecular Function | protein serine/threonine kinase activity | Interproscan |
| GO:0005524 all species → | Molecular Function | ATP binding | Interproscan |
| GO:0031267 all species → | Molecular Function | small GTPase binding | Interproscan |
| GO:0000281 all species → | Biological Process | mitotic cytokinesis | Interproscan |
| GO:0005737 all species → | Cellular Component | cytoplasm | Interproscan |
| GO:0005856 all species → | Cellular Component | cytoskeleton | Interproscan |
| GO:0007266 all species → | Biological Process | Rho protein signal transduction | Interproscan |
| GO:0018107 all species → | Biological Process | peptidyl-threonine phosphorylation | Interproscan |
| GO:0030866 all species → | Biological Process | cortical actin cytoskeleton organization | Interproscan |
| GO:0031032 all species → | Biological Process | actomyosin structure organization | Interproscan |
| GO:0048598 all species → | Biological Process | embryonic morphogenesis | Interproscan |
| GO:0072518 all species → | Molecular Function | Rho-dependent protein serine/threonine kinase activity | Interproscan |
| GO:1901888 all species → | Biological Process | regulation of cell junction assembly | Interproscan |
asel_s0067.g48.t2.Transcript abundance of asel_s0067.g48.t2 across 24 RNA-seq samples of Acropora selago. This gene has no row in the species' RNA-seq expression matrix, so every value below is shown as zero — the matrix simply does not cover this transcript. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.
| Condition | Samples | TPM > 0 | Mean TPM | Max TPM | Mean, relative to max |
|---|---|---|---|---|---|
| coral larvae | 24 | 0 | 0.00 | 0.00 |
| SRA run | Condition | Tissue | Developmental stage | Treatment | Study | TPM |
|---|---|---|---|---|---|---|
| SRR14308004 | coral larvae | coral larvae | not recorded | not recorded | SRP315987 | 0.00 |
| SRR14308005 | coral larvae | coral larvae | not recorded | not recorded | SRP315987 | 0.00 |
| SRR14308006 | coral larvae | coral larvae | not recorded | not recorded | SRP315987 | 0.00 |
| SRR14308007 | coral larvae | coral larvae | not recorded | not recorded | SRP315987 | 0.00 |
| SRR14308008 | coral larvae | coral larvae | not recorded | not recorded | SRP315987 | 0.00 |
| SRR14308009 | coral larvae | coral larvae | not recorded | not recorded | SRP315987 | 0.00 |
| SRR14308010 | coral larvae | coral larvae | not recorded | not recorded | SRP315987 | 0.00 |
| SRR14308011 | coral larvae | coral larvae | not recorded | not recorded | SRP315987 | 0.00 |
| SRR14308012 | coral larvae | coral larvae | not recorded | not recorded | SRP315987 | 0.00 |
| SRR14308013 | coral larvae | coral larvae | not recorded | not recorded | SRP315987 | 0.00 |
| SRR14308014 | coral larvae | coral larvae | not recorded | not recorded | SRP315987 | 0.00 |
| SRR14308015 | coral larvae | coral larvae | not recorded | not recorded | SRP315987 | 0.00 |
| SRR14308016 | coral larvae | coral larvae | not recorded | not recorded | SRP315987 | 0.00 |
| SRR14308017 | coral larvae | coral larvae | not recorded | not recorded | SRP315987 | 0.00 |
| SRR14308018 | coral larvae | coral larvae | not recorded | not recorded | SRP315987 | 0.00 |
| SRR14308019 | coral larvae | coral larvae | not recorded | not recorded | SRP315987 | 0.00 |
| SRR14308020 | coral larvae | coral larvae | not recorded | not recorded | SRP315987 | 0.00 |
| SRR14308021 | coral larvae | coral larvae | not recorded | not recorded | SRP315987 | 0.00 |
| SRR14308022 | coral larvae | coral larvae | not recorded | not recorded | SRP315987 | 0.00 |
| SRR14308023 | coral larvae | coral larvae | not recorded | not recorded | SRP315987 | 0.00 |
| SRR14308024 | coral larvae | coral larvae | not recorded | not recorded | SRP315987 | 0.00 |
| SRR14308025 | coral larvae | coral larvae | not recorded | not recorded | SRP315987 | 0.00 |
| SRR14308026 | coral larvae | coral larvae | not recorded | not recorded | SRP315987 | 0.00 |
| SRR14308027 | coral larvae | coral larvae | not recorded | not recorded | SRP315987 | 0.00 |
Source: CnidoSite RNA-seq expression matrices (ASELA_TPM,
StringTie quantification over 24 runs), joined to SRA sample
metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped
by the descriptor carried in the expression matrix itself.
Genes whose expression across the transcriptome samples of Acropora selago tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.
| Direction | Partners | Most correlated partner | PCC |
|---|---|---|---|
| Positively correlated | 0 | not in this network | - |
| Negatively correlated | 0 | not in this network | - |
This gene has no edge at all in the Acropora selago network, in either direction — it is not one of the genes the network was built from (the network covers genes with enough expression variation across the transcriptome samples). The counts above are a property of the network, not a failed lookup.
Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list.
Whether this gene can be visualised in the single-cell atlases of Acropora selago, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.
No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.
Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.
| Sample | Methylation profile |
|---|---|
| Coral_Fragment_Parent | open |
| Larval_Pool_Offspring | open |
The DNA Methylation page locates this gene by scanning the bisulphite table, which holds one row per cytosine. For the largest datasets that scan takes a while to return; it does not mean the link is broken.
Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.
| Analysis | What it does | Status | |
|---|---|---|---|
| Primer design | Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed. | template found | open → |
| BLAST | Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start. | template found | open → |
| Expression heatmap | Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it. | no expression matrix | – |
| Gene family / orthogroup | Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue. | open → | |
| Gene set analysis | Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it. | open → |
