Detailed information of asel_s0398.g8.t1 in Acropora selago

Genomic Location: sc0000398_pilon:122370...155475
NR annotation: XP_044176473.1, THO complex subunit 2-like isoform X1 [Acropora millepora]
Species Acropora selago · all data for this species · gene families


 Gene Structure
More details in JBrowse  Sequence
CDS
Transcript
Protein
 UniProt (Swiss-Prot top hit)
UniProt accessionDescription
C1FXW9THO complex subunit 2 OS=Dasypus novemcinctus OX=9361 GN=THOC2 PE=3 SV=1
B0KWH8THO complex subunit 2 OS=Callithrix jacchus OX=9483 GN=THOC2 PE=3 SV=1
Q8NI27THO complex subunit 2 OS=Homo sapiens OX=9606 GN=THOC2 PE=1 SV=2
 Gene family
Family typeMembership / link
Orthogroup (gene family)OG0003728 (this species only) · gene tree & orthology

 Pfam domain
Pfam accessionPfam nameDescriptionTypeSource
PF11262
all species →
Tho2Transcription factor/nuclear export subunit protein 2FamilyInterproscan
PF11732
all species →
Thoc2Transcription- and export-related complex subunitFamilyInterproscan
PF16134
all species →
THOC2_NTHO complex subunit 2 N-terminusFamilyInterproscan

 InterPro
InterPro termTypeDescriptionSource
IPR021418
all species →
DomainTHO complex, subunitTHOC2, C-terminalInterproscan
IPR040007
all species →
FamilyTHO complex subunit 2Interproscan
IPR021726
all species →
DomainTHO complex, subunitTHOC2, N-terminalInterproscan
IPR032302
all species →
DomainTHO complex subunit 2, N-terminal domainInterproscan

 PANTHER
PANTHER termDescriptionSource
PTHR21597
all species →
THO2 PROTEINInterproscan

 Gene Ontology
GO termCategoryDescriptionSource
GO:0000347
all species →
Cellular ComponentTHO complexInterproscan
GO:0000445
all species →
Cellular ComponentTHO complex part of transcription export complexInterproscan
GO:0003729
all species →
Molecular FunctionmRNA bindingInterproscan
GO:0006397
all species →
Biological ProcessmRNA processingInterproscan
GO:0006406
all species →
Biological ProcessmRNA export from nucleusInterproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.
 KEGG pathway
KOEnzymeEnzyme IDPathwayMap IDSource
K12879THOC2; THO complex subunit 2-Spliceosomeko03041deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of asel_s0398.g8.t1 across 24 RNA-seq samples of Acropora selago. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

24Samples
23TPM > 0
1Conditions
27.0Max TPM
19.5Mean TPM

By condition

ConditionSamplesTPM > 0 Mean TPMMax TPMMean, relative to max
coral larvae 24 23 19.53 27.03

Per sample · hover a bar for the full sample record

Show the sample table (24 samples)
SRA runConditionTissueDevelopmental stage TreatmentStudyTPM
SRR14308018 coral larvae coral larvae not recorded not recorded SRP315987 27.03
SRR14308004 coral larvae coral larvae not recorded not recorded SRP315987 25.76
SRR14308013 coral larvae coral larvae not recorded not recorded SRP315987 25.62
SRR14308007 coral larvae coral larvae not recorded not recorded SRP315987 23.36
SRR14308021 coral larvae coral larvae not recorded not recorded SRP315987 22.22
SRR14308027 coral larvae coral larvae not recorded not recorded SRP315987 21.97
SRR14308010 coral larvae coral larvae not recorded not recorded SRP315987 21.90
SRR14308015 coral larvae coral larvae not recorded not recorded SRP315987 21.43
SRR14308026 coral larvae coral larvae not recorded not recorded SRP315987 20.67
SRR14308023 coral larvae coral larvae not recorded not recorded SRP315987 20.63
SRR14308012 coral larvae coral larvae not recorded not recorded SRP315987 20.37
SRR14308006 coral larvae coral larvae not recorded not recorded SRP315987 19.81
SRR14308009 coral larvae coral larvae not recorded not recorded SRP315987 19.38
SRR14308017 coral larvae coral larvae not recorded not recorded SRP315987 19.28
SRR14308011 coral larvae coral larvae not recorded not recorded SRP315987 19.23
SRR14308022 coral larvae coral larvae not recorded not recorded SRP315987 19.22
SRR14308016 coral larvae coral larvae not recorded not recorded SRP315987 18.56
SRR14308008 coral larvae coral larvae not recorded not recorded SRP315987 18.25
SRR14308019 coral larvae coral larvae not recorded not recorded SRP315987 18.20
SRR14308024 coral larvae coral larvae not recorded not recorded SRP315987 17.28
SRR14308025 coral larvae coral larvae not recorded not recorded SRP315987 16.63
SRR14308020 coral larvae coral larvae not recorded not recorded SRP315987 16.50
SRR14308014 coral larvae coral larvae not recorded not recorded SRP315987 15.50
SRR14308005 coral larvae coral larvae not recorded not recorded SRP315987 0.00

Source: CnidoSite RNA-seq expression matrices (ASELA_TPM, StringTie quantification over 24 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.

Co-expression network

Genes whose expression across the transcriptome samples of Acropora selago tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

DirectionPartnersMost correlated partnerPCC
Positively correlated24asel_s0239.g47.t10.922069136091514
Negatively correlated25asel_s0333.g16.t1-0.888497545809868

Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Acropora selago, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

DNA methylation (bisulphite samples)

SampleMethylation profile
Coral_Fragment_Parentopen
Larval_Pool_Offspringopen

The DNA Methylation page locates this gene by scanning the bisulphite table, which holds one row per cytosine. For the largest datasets that scan takes a while to return; it does not mean the link is broken.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

AnalysisWhat it doesStatus
Primer designDesign PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.template foundopen →
BLASTSearch this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.template foundopen →
Expression heatmapDraw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.readyopen →
Gene family / orthogroupLook this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.open →
Gene set analysisStart a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.open →
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