Detailed information of asel_s0400.g15.t1 in Acropora selago

Genomic Location: sc0000400_pilon:197676...216933
NR annotation: XP_029188737.2, ATPase family AAA domain-containing protein 2-like isoform X1 [Acropora millepora]
Species Acropora selago · all data for this species · gene families


 Gene Structure
More details in JBrowse  Sequence
CDS
Transcript
Protein
 UniProt (Swiss-Prot top hit)
UniProt accessionDescription
Q9ULI0ATPase family AAA domain-containing protein 2B OS=Homo sapiens OX=9606 GN=ATAD2B PE=1 SV=4
Q8CDM1ATPase family AAA domain-containing protein 2 OS=Mus musculus OX=10090 GN=Atad2 PE=1 SV=1
Q5RDX4ATPase family AAA domain-containing protein 2 OS=Pongo abelii OX=9601 GN=ATAD2 PE=2 SV=1
 Gene family
Family typeMembership / link
Orthogroup (gene family)OG0006118 (this species only) · gene tree & orthology

 Pfam domain
Pfam accessionPfam nameDescriptionTypeSource
PF17862
all species →
AAA_lid_3AAA+ lid domainDomainInterproscan
PF00004
all species →
AAAATPase family associated with various cellular activities (AAA)DomainInterproscan
PF00439
all species →
BromodomainBromodomainDomainInterproscan

 InterPro
InterPro termTypeDescriptionSource
IPR045199
all species →
FamilyATPase family AAA domain-containing protein ATAD2-likeInterproscan
IPR041569
all species →
DomainAAA ATPase, AAA+ lid domainInterproscan
IPR003593
all species →
DomainAAA+ ATPase domainInterproscan
IPR036427
all species →
Homologous_superfamilyBromodomain-like superfamilyInterproscan
IPR027417
all species →
Homologous_superfamilyP-loop containing nucleoside triphosphate hydrolaseInterproscan
IPR001487
all species →
DomainBromodomainInterproscan
IPR018359
all species →
Conserved_siteBromodomain, conserved siteInterproscan
IPR003959
all species →
DomainATPase, AAA-type, coreInterproscan
IPR003960
all species →
Conserved_siteATPase, AAA-type, conserved siteInterproscan

 PANTHER
PANTHER termDescriptionSource
PTHR23069
all species →
AAA DOMAIN-CONTAININGInterproscan

 Gene Ontology
GO termCategoryDescriptionSource
GO:0003682
all species →
Molecular Functionchromatin bindingInterproscan
GO:0005634
all species →
Cellular ComponentnucleusInterproscan
GO:0016887
all species →
Molecular FunctionATP hydrolysis activityInterproscan
GO:0042393
all species →
Molecular Functionhistone bindingInterproscan
GO:0045944
all species →
Biological Processpositive regulation of transcription by RNA polymerase IIInterproscan
GO:0005515
all species →
Molecular Functionprotein bindingInterproscan
GO:0005524
all species →
Molecular FunctionATP bindingInterproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.
 KEGG pathway
KOEnzymeEnzyme IDPathwayMap IDSource
K22531ATAD2; ATPase family AAA domain-containing protein 2EC:3.6.1.-
Enzymes with EC numbers-deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of asel_s0400.g15.t1 across 24 RNA-seq samples of Acropora selago. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

24Samples
22TPM > 0
1Conditions
9.6Max TPM
3.9Mean TPM

By condition

ConditionSamplesTPM > 0 Mean TPMMax TPMMean, relative to max
coral larvae 24 22 3.86 9.61

Per sample · hover a bar for the full sample record

Show the sample table (24 samples)
SRA runConditionTissueDevelopmental stage TreatmentStudyTPM
SRR14308018 coral larvae coral larvae not recorded not recorded SRP315987 9.61
SRR14308026 coral larvae coral larvae not recorded not recorded SRP315987 5.68
SRR14308015 coral larvae coral larvae not recorded not recorded SRP315987 5.51
SRR14308004 coral larvae coral larvae not recorded not recorded SRP315987 5.41
SRR14308007 coral larvae coral larvae not recorded not recorded SRP315987 5.15
SRR14308024 coral larvae coral larvae not recorded not recorded SRP315987 4.85
SRR14308006 coral larvae coral larvae not recorded not recorded SRP315987 4.70
SRR14308017 coral larvae coral larvae not recorded not recorded SRP315987 4.33
SRR14308011 coral larvae coral larvae not recorded not recorded SRP315987 4.10
SRR14308014 coral larvae coral larvae not recorded not recorded SRP315987 3.95
SRR14308012 coral larvae coral larvae not recorded not recorded SRP315987 3.95
SRR14308022 coral larvae coral larvae not recorded not recorded SRP315987 3.75
SRR14308010 coral larvae coral larvae not recorded not recorded SRP315987 3.66
SRR14308013 coral larvae coral larvae not recorded not recorded SRP315987 3.57
SRR14308021 coral larvae coral larvae not recorded not recorded SRP315987 3.45
SRR14308019 coral larvae coral larvae not recorded not recorded SRP315987 3.33
SRR14308027 coral larvae coral larvae not recorded not recorded SRP315987 3.27
SRR14308008 coral larvae coral larvae not recorded not recorded SRP315987 3.07
SRR14308016 coral larvae coral larvae not recorded not recorded SRP315987 3.06
SRR14308025 coral larvae coral larvae not recorded not recorded SRP315987 3.05
SRR14308023 coral larvae coral larvae not recorded not recorded SRP315987 2.75
SRR14308020 coral larvae coral larvae not recorded not recorded SRP315987 2.42
SRR14308005 coral larvae coral larvae not recorded not recorded SRP315987 0.00
SRR14308009 coral larvae coral larvae not recorded not recorded SRP315987 0.00

Source: CnidoSite RNA-seq expression matrices (ASELA_TPM, StringTie quantification over 24 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.

Co-expression network

Genes whose expression across the transcriptome samples of Acropora selago tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

DirectionPartnersMost correlated partnerPCC
Positively correlated30asel_s0017.g23.t10.933261170914353
Negatively correlated3asel_s0156.g22.t1-0.792336659711511

Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Acropora selago, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

DNA methylation (bisulphite samples)

SampleMethylation profile
Coral_Fragment_Parentopen
Larval_Pool_Offspringopen

The DNA Methylation page locates this gene by scanning the bisulphite table, which holds one row per cytosine. For the largest datasets that scan takes a while to return; it does not mean the link is broken.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

AnalysisWhat it doesStatus
Primer designDesign PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.template foundopen →
BLASTSearch this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.template foundopen →
Expression heatmapDraw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.readyopen →
Gene family / orthogroupLook this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.open →
Gene set analysisStart a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.open →
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