Gene detail

Detailed information of c0545.g013.t1.p1 in Palythoa mizigama

Genomic Location: :...
NR annotation: XP_032227567.2, guanine nucleotide exchange factor DBS isoform X2 [Nematostella vectensis]

Gene Structure

Sequence

Uniprot

Uniprot term	Description
O15068	Guanine nucleotide exchange factor DBS OS=Homo sapiens OX=9606 GN=MCF2L PE=1 SV=2
Q63406	Guanine nucleotide exchange factor DBS OS=Rattus norvegicus OX=10116 GN=Mcf2l PE=1 SV=3
Q64096	Guanine nucleotide exchange factor DBS OS=Mus musculus OX=10090 GN=Mcf2l PE=1 SV=2

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF00169	PH	PH domain	Domain	Interproscan
PF13716	CRAL_TRIO_2	Divergent CRAL/TRIO domain	Domain	Interproscan
PF00621	RhoGEF	RhoGEF domain	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR001849	Domain	Pleckstrin homology domain	Interproscan
IPR035899	Homologous_superfamily	Dbl homology (DH) domain superfamily	Interproscan
IPR051336	Family	Rho GTPase-activating Guanine Nucleotide Exchange Factors	Interproscan
IPR018159	Repeat	Spectrin/alpha-actinin	Interproscan
IPR036865	Homologous_superfamily	CRAL-TRIO lipid binding domain superfamily	Interproscan
IPR001251	Domain	CRAL-TRIO lipid binding domain	Interproscan
IPR000219	Domain	Dbl homology (DH) domain	Interproscan
IPR011993	Homologous_superfamily	PH-like domain superfamily	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR22826	RHO GUANINE EXCHANGE FACTOR-RELATED	Interproscan

Gene Ontology

GO terms	Category	Description	Source
GO:0005085	Molecular Function	guanyl-nucleotide exchange factor activity	Interproscan
GO:0005737	Cellular Component	cytoplasm	Interproscan

KEGG pathway

KO	Enzyme	Enzyme ID	pathway	mapID	Source
K20685	MCF2, ARHGEF14_21_22; guanine nucleotide exchange factor MCF2	-	Membrane trafficking	ko04131	deepkoala