Genomic Location: Ap12:10164369...10169467
NR annotation: XP_020601823.1, tuberin-like [Orbicella faveolata]
| CDS | ||||
| evm.model.Ap12.951 | ||||
| Transcript |
| evm.model.Ap12.951 |
| Protein |
| evm.model.Ap12.951 |
| Uniprot term | Description |
|---|---|
| P49815 | Tuberin OS=Homo sapiens OX=9606 GN=TSC2 PE=1 SV=2 |
| Q61037 | Tuberin OS=Mus musculus OX=10090 GN=Tsc2 PE=1 SV=1 |
| P49816 | Tuberin OS=Rattus norvegicus OX=10116 GN=Tsc2 PE=1 SV=1 |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF11864 | DUF3384 | Domain of unknown function (DUF3384) | Family | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR024584 | Domain | Tuberin, N-terminal | Interproscan |
| IPR027107 | Family | Tuberin/Ral GTPase-activating protein subunit alpha | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR10063 | TUBERIN | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0005096 | Molecular Function | GTPase activator activity | Interproscan |
| GO:0005634 | Cellular Component | nucleus | Interproscan |
| GO:0005737 | Cellular Component | cytoplasm | Interproscan |
| GO:0030178 | Biological Process | negative regulation of Wnt signaling pathway | Interproscan |
| GO:0032007 | Biological Process | negative regulation of TOR signaling | Interproscan |
| GO:0033596 | Cellular Component | TSC1-TSC2 complex | Interproscan |
| GO:0043547 | Biological Process | positive regulation of GTPase activity | Interproscan |
| GO:0046627 | Biological Process | negative regulation of insulin receptor signaling pathway | Interproscan |
| GO:0051726 | Biological Process | regulation of cell cycle | Interproscan |
| GO:0051898 | Biological Process | negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction | Interproscan |