Genomic Location: Ap4:35673140...35697514
NR annotation: XP_022800076.1, nibrin-like isoform X1 [Stylophora pistillata]
| CDS | |||||
| evm.model.Ap4.5092 | |||||
| Transcript |
| evm.model.Ap4.5092 |
| Protein |
| evm.model.Ap4.5092 |
| Uniprot term | Description |
|---|---|
| Q6XV80 | Nibrin OS=Xenopus laevis OX=8355 GN=nbn.L PE=1 SV=1 |
| O60934 | Nibrin OS=Homo sapiens OX=9606 GN=NBN PE=1 SV=1 |
| Q5RCV3 | Nibrin OS=Pongo abelii OX=9601 GN=NBN PE=2 SV=2 |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF00498 | FHA | FHA domain | Family | Interproscan |
| PF16770 | RTT107_BRCT_5 | Regulator of Ty1 transposition protein 107 BRCT domain | Domain | Interproscan |
| PF08599 | Nbs1_C | DNA damage repair protein Nbs1 | Family | Interproscan |
| PF16508 | NIBRIN_BRCT_II | Second BRCT domain on Nijmegen syndrome breakage protein | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR013908 | Domain | Nibrin, C-terminal | Interproscan |
| IPR000253 | Domain | Forkhead-associated (FHA) domain | Interproscan |
| IPR040227 | Family | Nibrin-related | Interproscan |
| IPR043014 | Homologous_superfamily | Nibrin, second BRCT domain superfamily | Interproscan |
| IPR036420 | Homologous_superfamily | BRCT domain superfamily | Interproscan |
| IPR001357 | Domain | BRCT domain | Interproscan |
| IPR008984 | Homologous_superfamily | SMAD/FHA domain superfamily | Interproscan |
| IPR032429 | Domain | Nibrin, second BRCT domain | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR12162 | NIBRIN-RELATED | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0005515 | Molecular Function | protein binding | Interproscan |
| GO:0000724 | Biological Process | double-strand break repair via homologous recombination | Interproscan |
| GO:0003684 | Molecular Function | damaged DNA binding | Interproscan |
| GO:0006302 | Biological Process | double-strand break repair | Interproscan |
| GO:0007095 | Biological Process | mitotic G2 DNA damage checkpoint signaling | Interproscan |
| GO:0030870 | Cellular Component | Mre11 complex | Interproscan |
| GO:0032508 | Biological Process | DNA duplex unwinding | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K10867 | NBN, NBS1; nibrin | - | DNA repair and recombination proteins | ko03400 | deepkoala |
Maintained by Dr. Jiajie She from Prof. Longjun Wu's Lab & Prof. Pei-yuan Qian's Lab
Hong Kong Branch of the Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou)
Hong Kong University of Science and Technology
Clear Water Bay, Kowloon, Hong Kong
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