Genomic Location: Ap4:9426939...9435892
NR annotation: KAJ7351036.1, isocitrate dehydrogenase (NAD(+)) idh1 [Desmophyllum pertusum]
| CDS | |||||
| evm.model.Ap4.897 | |||||
| Transcript |
| evm.model.Ap4.897 |
| Protein |
| evm.model.Ap4.897 |
| Uniprot term | Description |
|---|---|
| Q6XUZ5 | Isocitrate dehydrogenase [NADP] cytoplasmic OS=Ovis aries OX=9940 GN=IDH1 PE=2 SV=1 |
| Q9XSG3 | Isocitrate dehydrogenase [NADP] cytoplasmic OS=Bos taurus OX=9913 GN=IDH1 PE=2 SV=1 |
| Q5R9C5 | Isocitrate dehydrogenase [NADP] cytoplasmic OS=Pongo abelii OX=9601 GN=IDH1 PE=2 SV=2 |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF00180 | Iso_dh | Isocitrate/isopropylmalate dehydrogenase | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR024084 | Domain | Isopropylmalate dehydrogenase-like domain | Interproscan |
| IPR004790 | Family | Isocitrate dehydrogenase NADP-dependent | Interproscan |
| IPR019818 | Conserved_site | Isocitrate/isopropylmalate dehydrogenase, conserved site | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR11822 | NADP-SPECIFIC ISOCITRATE DEHYDROGENASE | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0004450 | Molecular Function | isocitrate dehydrogenase (NADP+) activity | Interproscan |
| GO:0006102 | Biological Process | isocitrate metabolic process | Interproscan |
| GO:0005739 | Cellular Component | mitochondrion | Interproscan |
| GO:0005777 | Cellular Component | peroxisome | Interproscan |
| GO:0005829 | Cellular Component | cytosol | Interproscan |
| GO:0006739 | Biological Process | NADP metabolic process | Interproscan |
| GO:0000287 | Molecular Function | magnesium ion binding | Interproscan |
| GO:0016616 | Molecular Function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | Interproscan |
| GO:0051287 | Molecular Function | NAD binding | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K00031 | IDH1, IDH2, icd; isocitrate dehydrogenase | EC:1.1.1.42 | Central carbon metabolism in cancer | ko05230 | deepkoala |