Gene detail

Detailed information of evm.model.Ap8.2037 in Astrangia poculata

Genomic Location: Ap8:22460545...22472859
NR annotation: XP_020621630.1, porphobilinogen deaminase-like [Orbicella faveolata]

Gene Structure

Sequence

Uniprot

Uniprot term	Description
Q2KIN5	Porphobilinogen deaminase OS=Bos taurus OX=9913 GN=HMBS PE=2 SV=1
P08397	Porphobilinogen deaminase OS=Homo sapiens OX=9606 GN=HMBS PE=1 SV=2
P22907	Porphobilinogen deaminase OS=Mus musculus OX=10090 GN=Hmbs PE=1 SV=2

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF01379	Porphobil_deam	Porphobilinogen deaminase, dipyromethane cofactor binding domain	Domain	Interproscan
PF03900	Porphobil_deamC	Porphobilinogen deaminase, C-terminal domain	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR036803	Homologous_superfamily	Porphobilinogen deaminase, C-terminal domain superfamily	Interproscan
IPR000860	Family	Porphobilinogen deaminase	Interproscan
IPR022419	Binding_site	Porphobilinogen deaminase, dipyrromethane cofactor binding site	Interproscan
IPR022417	Domain	Porphobilinogen deaminase, N-terminal	Interproscan
IPR022418	Domain	Porphobilinogen deaminase, C-terminal	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR11557	PORPHOBILINOGEN DEAMINASE	Interproscan

Gene Ontology

GO terms	Category	Description	Source
GO:0004418	Molecular Function	hydroxymethylbilane synthase activity	Interproscan
GO:0033014	Biological Process	tetrapyrrole biosynthetic process	Interproscan
GO:0005737	Cellular Component	cytoplasm	Interproscan
GO:0006783	Biological Process	heme biosynthetic process	Interproscan
GO:0018160	Biological Process	peptidyl-pyrromethane cofactor linkage	Interproscan

KEGG pathway

KO	Enzyme	Enzyme ID	pathway	mapID	Source
K01749	hemC, HMBS; hydroxymethylbilane synthase	EC:2.5.1.61	Porphyrin metabolism	ko00860	deepkoala