Genomic Location: Ap9:4304939...4323405
NR annotation: KAJ7371490.1, NPC intracellular cholesterol transporter 1 [Desmophyllum pertusum]
| CDS | |||||
| evm.model.Ap9.399 | |||||
| Transcript |
| evm.model.Ap9.399 |
| Protein |
| evm.model.Ap9.399 |
| Uniprot term | Description |
|---|---|
| O35604 | NPC intracellular cholesterol transporter 1 OS=Mus musculus OX=10090 GN=Npc1 PE=1 SV=2 |
| O15118 | NPC intracellular cholesterol transporter 1 OS=Homo sapiens OX=9606 GN=NPC1 PE=1 SV=2 |
| P56941 | NPC intracellular cholesterol transporter 1 OS=Sus scrofa OX=9823 GN=NPC1 PE=2 SV=1 |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF02460 | Patched | Patched family | Family | Interproscan |
| PF12349 | Sterol-sensing | Sterol-sensing domain of SREBP cleavage-activation | Family | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR000731 | Domain | Sterol-sensing domain | Interproscan |
| IPR003392 | Family | Protein patched/dispatched | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR45727 | NPC INTRACELLULAR CHOLESTEROL TRANSPORTER 1 | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0016020 | Cellular Component | membrane | Interproscan |
| GO:0015918 | Biological Process | sterol transport | Interproscan |
| GO:0032934 | Molecular Function | sterol binding | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K12385 | NPC1; Niemann-Pick C1 protein | - | Transporters | ko02000 | deepkoala |
Maintained by Dr. Jiajie She from Prof. Longjun Wu's Lab & Prof. Pei-yuan Qian's Lab
Hong Kong Branch of the Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou)
Hong Kong University of Science and Technology
Clear Water Bay, Kowloon, Hong Kong
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