Genomic Location: Chr02:22227009...22262110
NR annotation: XP_028405374.1, NADPH oxidase 5-like [Dendronephthya gigantea]
Species Hemicorallium imperiale · all data for this species · gene families
evm.model.Chr02.856 in HIMPE (the gene ID may belong to a different isoform naming scheme). Try the gene search.| UniProt accession | Description |
|---|---|
| Q96PH1 | NADPH oxidase 5 OS=Homo sapiens OX=9606 GN=NOX5 PE=1 SV=1 |
| Q54F44 | Superoxide-generating NADPH oxidase heavy chain subunit C OS=Dictyostelium discoideum OX=44689 GN=noxC PE=2 SV=1 |
| Q8CIZ9 | NADPH oxidase 1 OS=Mus musculus OX=10090 GN=Nox1 PE=1 SV=2 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0009466 (this species only) · gene tree & orthology |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF13202 all species → | EF-hand_5 | EF hand | Domain | Interproscan |
| PF13499 all species → | EF-hand_7 | EF-hand domain pair | Domain | Interproscan |
| PF08030 all species → | NAD_binding_6 | Ferric reductase NAD binding domain | Domain | Interproscan |
| PF08022 all species → | FAD_binding_8 | FAD-binding domain | Domain | Interproscan |
| PF01794 all species → | Ferric_reduct | Ferric reductase like transmembrane component | Family | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR002048 all species → | Domain | EF-hand domain | Interproscan |
| IPR018247 all species → | Binding_site | EF-Hand 1, calcium-binding site | Interproscan |
| IPR017938 all species → | Homologous_superfamily | Riboflavin synthase-like beta-barrel | Interproscan |
| IPR011992 all species → | Homologous_superfamily | EF-hand domain pair | Interproscan |
| IPR013121 all species → | Domain | Ferric reductase, NAD binding domain | Interproscan |
| IPR039261 all species → | Homologous_superfamily | Ferredoxin-NADP reductase (FNR), nucleotide-binding domain | Interproscan |
| IPR000778 all species → | Family | Cytochrome b245, heavy chain | Interproscan |
| IPR013112 all species → | Domain | FAD-binding 8 | Interproscan |
| IPR017927 all species → | Domain | FAD-binding domain, ferredoxin reductase-type | Interproscan |
| IPR013130 all species → | Domain | Ferric reductase transmembrane component-like domain | Interproscan |
| IPR050369 all species → | Family | Respiratory burst oxidase/Ferric reductase | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR11972 all species → | NADPH OXIDASE | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0005509 all species → | Molecular Function | calcium ion binding | Interproscan |
| GO:0016491 all species → | Molecular Function | oxidoreductase activity | Interproscan |
| GO:0016020 all species → | Cellular Component | membrane | Interproscan |
| GO:0005886 all species → | Cellular Component | plasma membrane | Interproscan |
| GO:0006952 all species → | Biological Process | defense response | Interproscan |
| GO:0016175 all species → | Molecular Function | superoxide-generating NAD(P)H oxidase activity | Interproscan |
| GO:0042554 all species → | Biological Process | superoxide anion generation | Interproscan |
| GO:0043020 all species → | Cellular Component | NADPH oxidase complex | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K21424 | NOX5; NADPH oxidase 5 | EC:1.6.3.- | Membrane trafficking | ko04131 | deepkoala |
Genes whose expression across the transcriptome samples of Hemicorallium imperiale tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.
No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.
Whether this gene can be visualised in the single-cell atlases of Hemicorallium imperiale, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.
No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.
Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.
No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.
Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.
| Analysis | What it does | Status | |
|---|---|---|---|
| Primer design | Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed. | not in the sequence table | open → |
| BLAST | Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start. | not in the sequence table | open → |
| Expression heatmap | Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it. | no expression matrix | – |
| Gene family / orthogroup | Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue. | open → | |
| Gene set analysis | Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it. | open → |
