Genomic Location: Chr12:12188545...12238525
NR annotation: XP_028408151.1, tyrosine-protein phosphatase non-receptor type 20-like [Dendronephthya gigantea]
| CDS | ||||
| Transcript |
| Protein |
| Uniprot term | Description | |||
|---|---|---|---|---|
| P61371 | Insulin gene enhancer protein ISL-1 OS=Homo sapiens OX=9606 GN=ISL1 PE=1 SV=1 | |||
| P61373 | Insulin gene enhancer protein ISL-1 OS=Mesocricetus auratus OX=10036 GN=ISL1 PE=2 SV=1 | |||
| P61372 | Insulin gene enhancer protein ISL-1 OS=Mus musculus OX=10090 GN=Isl1 PE=1 SV=1 |
| Gene family | Subfamily |
|---|---|
| Transcription Factors Family | Homeobox |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF00412 | LIM | LIM domain | Domain | Interproscan |
| PF00102 | Y_phosphatase | Protein-tyrosine phosphatase | Domain | Interproscan |
| PF00046 | Homeodomain | Homeodomain | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR001356 | Domain | Homeobox domain | Interproscan |
| IPR017970 | Conserved_site | Homeobox, conserved site | Interproscan |
| IPR000242 | Domain | Tyrosine-specific protein phosphatase, PTPase domain | Interproscan |
| IPR029021 | Homologous_superfamily | Protein-tyrosine phosphatase-like | Interproscan |
| IPR001781 | Domain | Zinc finger, LIM-type | Interproscan |
| IPR047244 | Domain | Insulin gene enhancer protein ISL-1/2-like, LIM domain1 | Interproscan |
| IPR047169 | Family | Insulin gene enhancer protein ISL-1/2-like | Interproscan |
| IPR003595 | Domain | Protein-tyrosine phosphatase, catalytic | Interproscan |
| IPR000387 | Domain | Tyrosine-specific protein phosphatases domain | Interproscan |
| IPR009057 | Homologous_superfamily | Homeobox-like domain superfamily | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR24204 | INSULIN GENE ENHANCER PROTEIN | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0003677 | Molecular Function | DNA binding | Interproscan |
| GO:0000981 | Molecular Function | DNA-binding transcription factor activity, RNA polymerase II-specific | Interproscan |
| GO:0006355 | Biological Process | regulation of DNA-templated transcription | Interproscan |
| GO:0004725 | Molecular Function | protein tyrosine phosphatase activity | Interproscan |
| GO:0006470 | Biological Process | protein dephosphorylation | Interproscan |
| GO:0007409 | Biological Process | axonogenesis | Interproscan |
| GO:0045944 | Biological Process | positive regulation of transcription by RNA polymerase II | Interproscan |
| GO:0048665 | Biological Process | neuron fate specification | Interproscan |
| GO:0016311 | Biological Process | dephosphorylation | Interproscan |