Genomic Location: Chr14:1571813...1604571
NR annotation: CAB3982238.1, AFG3 2 [Paramuricea clavata]
| CDS | ||||
| Transcript |
| Protein |
| Uniprot term | Description |
|---|---|
| Q9Y4W6 | Mitochondrial inner membrane m-AAA protease component AFG3L2 OS=Homo sapiens OX=9606 GN=AFG3L2 PE=1 SV=2 |
| Q2KJI7 | Mitochondrial inner membrane m-AAA protease component AFG3L2 OS=Bos taurus OX=9913 GN=AFG3L2 PE=2 SV=1 |
| Q8JZQ2 | Mitochondrial inner membrane m-AAA protease component AFG3L2 OS=Mus musculus OX=10090 GN=Afg3l2 PE=1 SV=1 |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF12796 | Ank_2 | Ankyrin repeats (3 copies) | Repeat | Interproscan |
| PF13181 | TPR_8 | Tetratricopeptide repeat | Repeat | Interproscan |
| PF01434 | Peptidase_M41 | Peptidase family M41 | Domain | Interproscan |
| PF06480 | FtsH_ext | FtsH Extracellular | Family | Interproscan |
| PF13516 | LRR_6 | Leucine Rich repeat | Repeat | Interproscan |
| PF13424 | TPR_12 | Tetratricopeptide repeat | Repeat | Interproscan |
| PF17862 | AAA_lid_3 | AAA+ lid domain | Domain | Interproscan |
| PF00004 | AAA | ATPase family associated with various cellular activities (AAA) | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR052311 | Family | MMS22L-TONSL complex component | Interproscan |
| IPR002110 | Repeat | Ankyrin repeat | Interproscan |
| IPR019734 | Repeat | Tetratricopeptide repeat | Interproscan |
| IPR032675 | Homologous_superfamily | Leucine-rich repeat domain superfamily | Interproscan |
| IPR011990 | Homologous_superfamily | Tetratricopeptide-like helical domain superfamily | Interproscan |
| IPR000642 | Domain | Peptidase M41 | Interproscan |
| IPR036770 | Homologous_superfamily | Ankyrin repeat-containing domain superfamily | Interproscan |
| IPR003593 | Domain | AAA+ ATPase domain | Interproscan |
| IPR027417 | Homologous_superfamily | P-loop containing nucleoside triphosphate hydrolase | Interproscan |
| IPR011546 | Domain | Peptidase M41, FtsH extracellular | Interproscan |
| IPR005936 | Family | ATP-dependent zinc metalloprotease, FtsH | Interproscan |
| IPR001611 | Repeat | Leucine-rich repeat | Interproscan |
| IPR041569 | Domain | AAA ATPase, AAA+ lid domain | Interproscan |
| IPR003960 | Conserved_site | ATPase, AAA-type, conserved site | Interproscan |
| IPR037219 | Homologous_superfamily | Peptidase M41-like | Interproscan |
| IPR003959 | Domain | ATPase, AAA-type, core | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR46358 | TONSOKU-LIKE PROTEIN | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0000724 | Biological Process | double-strand break repair via homologous recombination | Interproscan |
| GO:0031297 | Biological Process | replication fork processing | Interproscan |
| GO:0043596 | Cellular Component | nuclear replication fork | Interproscan |
| GO:0005515 | Molecular Function | protein binding | Interproscan |
| GO:0004176 | Molecular Function | ATP-dependent peptidase activity | Interproscan |
| GO:0004222 | Molecular Function | metalloendopeptidase activity | Interproscan |
| GO:0005524 | Molecular Function | ATP binding | Interproscan |
| GO:0006508 | Biological Process | proteolysis | Interproscan |
| GO:0016887 | Molecular Function | ATP hydrolysis activity | Interproscan |
| GO:0008270 | Molecular Function | zinc ion binding | Interproscan |
| GO:0016020 | Cellular Component | membrane | Interproscan |