Genomic Location: Chr17:7031233...7057985
NR annotation: XP_028398085.1, histidine ammonia-lyase-like isoform X1 [Dendronephthya gigantea]
Species Hemicorallium imperiale · all data for this species · gene families
evm.model.Chr17.294 in HIMPE (the gene ID may belong to a different isoform naming scheme). Try the gene search.| UniProt accession | Description |
|---|---|
| P42357 | Histidine ammonia-lyase OS=Homo sapiens OX=9606 GN=HAL PE=1 SV=1 |
| A7YWP4 | Histidine ammonia-lyase OS=Bos taurus OX=9913 GN=HAL PE=2 SV=1 |
| P21213 | Histidine ammonia-lyase OS=Rattus norvegicus OX=10116 GN=Hal PE=1 SV=1 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0002236 (this species only) · gene tree & orthology |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF12053 all species → | Par3_HAL_N_term | N-terminal of Par3 and HAL proteins | Family | Interproscan |
| PF00221 all species → | Lyase_aromatic | Aromatic amino acid lyase | Family | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR001106 all species → | Family | Aromatic amino acid lyase | Interproscan |
| IPR008948 all species → | Homologous_superfamily | L-Aspartase-like | Interproscan |
| IPR022313 all species → | Active_site | Phenylalanine/histidine ammonia-lyases, active site | Interproscan |
| IPR005921 all species → | Family | Histidine ammonia-lyase | Interproscan |
| IPR021922 all species → | Domain | Par3/HAL, N-terminal | Interproscan |
| IPR024083 all species → | Homologous_superfamily | Fumarase/histidase, N-terminal | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR10362 all species → | HISTIDINE AMMONIA-LYASE | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0003824 all species → | Molecular Function | catalytic activity | Interproscan |
| GO:0016841 all species → | Molecular Function | ammonia-lyase activity | Interproscan |
| GO:0004397 all species → | Molecular Function | histidine ammonia-lyase activity | Interproscan |
| GO:0005737 all species → | Cellular Component | cytoplasm | Interproscan |
| GO:0006548 all species → | Biological Process | L-histidine catabolic process | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K01745 | hutH, HAL; histidine ammonia-lyase | EC:4.3.1.3 | Histidine metabolism | ko00340 | deepkoala |
Genes whose expression across the transcriptome samples of Hemicorallium imperiale tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.
No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.
Whether this gene can be visualised in the single-cell atlases of Hemicorallium imperiale, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.
No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.
Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.
No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.
Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.
| Analysis | What it does | Status | |
|---|---|---|---|
| Primer design | Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed. | not in the sequence table | open → |
| BLAST | Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start. | not in the sequence table | open → |
| Expression heatmap | Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it. | no expression matrix | – |
| Gene family / orthogroup | Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue. | open → | |
| Gene set analysis | Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it. | open → |
