Genomic Location: Chr18:3689870...3789065
NR annotation: CAB3992156.1, E3 ubiquitin- ligase UBR5 isoform X2 [Paramuricea clavata]
Species abbreviation HIMPE · all data for this species · gene families
| CDS |
| evm.model.Chr18.162 |
| Transcript |
| evm.model.Chr18.162 |
| Protein |
| evm.model.Chr18.162 |
| UniProt accession | Description |
|---|---|
| Q80TP3 | E3 ubiquitin-protein ligase UBR5 OS=Mus musculus OX=10090 GN=Ubr5 PE=1 SV=2 |
| Q62671 | E3 ubiquitin-protein ligase UBR5 OS=Rattus norvegicus OX=10116 GN=Ubr5 PE=1 SV=3 |
| O95071 | E3 ubiquitin-protein ligase UBR5 OS=Homo sapiens OX=9606 GN=UBR5 PE=1 SV=2 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0002381 (this species only) |
| Ubiquitin family | E3|E3 activity|HECT · all ubiquitin genes in this species |
| Ubiquitin family | E3|E3 activity|UBR-box · all ubiquitin genes in this species |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF11547 all species → | E3_UbLigase_EDD | E3 ubiquitin ligase EDD | Domain | Interproscan |
| PF05502 all species → | Dynactin_p62 | Dynactin p62 family | Family | Interproscan |
| PF00632 all species → | HECT | HECT-domain (ubiquitin-transferase) | Domain | Interproscan |
| PF00069 all species → | Pkinase | Protein kinase domain | Domain | Interproscan |
| PF00658 all species → | PABP | Poly-adenylate binding protein, unique domain | Family | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR003126 all species → | Domain | Zinc finger, UBR-type | Interproscan |
| IPR024725 all species → | Domain | E3 ubiquitin-protein ligase UBR5, ubiquitin-associated domain | Interproscan |
| IPR002004 all species → | Domain | Polyadenylate-binding protein/Hyperplastic disc protein | Interproscan |
| IPR003527 all species → | Conserved_site | Mitogen-activated protein (MAP) kinase, conserved site | Interproscan |
| IPR047503 all species → | Domain | E3 ubiquitin-protein ligase UBR5, UBR-box | Interproscan |
| IPR009091 all species → | Homologous_superfamily | Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II | Interproscan |
| IPR008603 all species → | Family | Dynactin subunit 4 | Interproscan |
| IPR000569 all species → | Domain | HECT domain | Interproscan |
| IPR035983 all species → | Homologous_superfamily | HECT, E3 ligase catalytic domain | Interproscan |
| IPR011009 all species → | Homologous_superfamily | Protein kinase-like domain superfamily | Interproscan |
| IPR008271 all species → | Active_site | Serine/threonine-protein kinase, active site | Interproscan |
| IPR036053 all species → | Homologous_superfamily | PABC (PABP) domain | Interproscan |
| IPR000719 all species → | Domain | Protein kinase domain | Interproscan |
| IPR008351 all species → | Family | Mitogen-activated protein (MAP) kinase, JNK | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR46276 all species → | E3 UBIQUITIN-PROTEIN LIGASE UBR5 | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0008270 all species → | Molecular Function | zinc ion binding | Interproscan |
| GO:0043130 all species → | Molecular Function | ubiquitin binding | Interproscan |
| GO:0003723 all species → | Molecular Function | RNA binding | Interproscan |
| GO:0000209 all species → | Biological Process | protein polyubiquitination | Interproscan |
| GO:0005634 all species → | Cellular Component | nucleus | Interproscan |
| GO:0005737 all species → | Cellular Component | cytoplasm | Interproscan |
| GO:0034450 all species → | Molecular Function | ubiquitin-ubiquitin ligase activity | Interproscan |
| GO:0090263 all species → | Biological Process | positive regulation of canonical Wnt signaling pathway | Interproscan |
| GO:0004707 all species → | Molecular Function | MAP kinase activity | Interproscan |
| GO:0005524 all species → | Molecular Function | ATP binding | Interproscan |
| GO:0006468 all species → | Biological Process | protein phosphorylation | Interproscan |
| GO:0005869 all species → | Cellular Component | dynactin complex | Interproscan |
| GO:0004842 all species → | Molecular Function | ubiquitin-protein transferase activity | Interproscan |
| GO:0004672 all species → | Molecular Function | protein kinase activity | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K10593 | EDD1, UBR5; E3 ubiquitin-protein ligase EDD1 | EC:2.3.2.26 | Ubiquitin system | ko04121 | deepkoala |