Genomic Location: chr16:1842851...1891703
NR annotation: XP_047144921.1, disks large homolog 5-like [Hydra vulgaris]
| CDS | |||||
| evm.model.ptg000024l.780 | |||||
| Transcript |
| evm.model.ptg000024l.780 |
| Protein |
| evm.model.ptg000024l.780 |
| Uniprot term | Description | ||||
|---|---|---|---|---|---|
| Q8TDM6 | Disks large homolog 5 OS=Homo sapiens OX=9606 GN=DLG5 PE=1 SV=4 | ||||
| E9Q9R9 | Disks large homolog 5 OS=Mus musculus OX=10090 GN=Dlg5 PE=1 SV=1 | ||||
| Q07157 | Tight junction protein 1 OS=Homo sapiens OX=9606 GN=TJP1 PE=1 SV=3 |
| Gene family | Subfamily |
|---|---|
| Ubiquitin Family | UBD|Other|SH3 |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF00018 | SH3_1 | SH3 domain | Domain | Interproscan |
| PF00595 | PDZ | PDZ domain | Domain | Interproscan |
| PF00625 | Guanylate_kin | Guanylate kinase | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR001478 | Domain | PDZ domain | Interproscan |
| IPR036034 | Homologous_superfamily | PDZ superfamily | Interproscan |
| IPR027417 | Homologous_superfamily | P-loop containing nucleoside triphosphate hydrolase | Interproscan |
| IPR035537 | Domain | Disks large homologue 5, SH3 domain | Interproscan |
| IPR001452 | Domain | SH3 domain | Interproscan |
| IPR036028 | Homologous_superfamily | SH3-like domain superfamily | Interproscan |
| IPR011029 | Homologous_superfamily | Death-like domain superfamily | Interproscan |
| IPR008145 | Domain | Guanylate kinase/L-type calcium channel beta subunit | Interproscan |
| IPR008144 | Domain | Guanylate kinase-like domain | Interproscan |
| IPR053004 | Family | MAGUK Family Regulators of Signaling Pathways | Interproscan |
| IPR001315 | Domain | CARD domain | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR46360 | DISKS LARGE HOMOLOG 5 | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0005515 | Molecular Function | protein binding | Interproscan |
| GO:0005886 | Cellular Component | plasma membrane | Interproscan |
| GO:0035331 | Biological Process | negative regulation of hippo signaling | Interproscan |
| GO:0042981 | Biological Process | regulation of apoptotic process | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K24050 | DLG5; discs large protein 5 | - | Hippo signaling pathway - fly | ko04391 | deepkoala |