Genomic Location: chr11:930986...938253
NR annotation: XP_027040711.1, hydroxymethylglutaryl-CoA synthase 1-like [Pocillopora damicornis]
| CDS | |||||
| evm.model.ptg000031l.512 | |||||
| Transcript |
| evm.model.ptg000031l.512 |
| Protein |
| evm.model.ptg000031l.512 |
| Uniprot term | Description |
|---|---|
| Q5R7Z9 | Hydroxymethylglutaryl-CoA synthase, cytoplasmic OS=Pongo abelii OX=9601 GN=HMGCS1 PE=2 SV=1 |
| Q01581 | Hydroxymethylglutaryl-CoA synthase, cytoplasmic OS=Homo sapiens OX=9606 GN=HMGCS1 PE=1 SV=2 |
| P17425 | Hydroxymethylglutaryl-CoA synthase, cytoplasmic OS=Rattus norvegicus OX=10116 GN=Hmgcs1 PE=1 SV=1 |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF01154 | HMG_CoA_synt_N | Hydroxymethylglutaryl-coenzyme A synthase N terminal | Domain | Interproscan |
| PF08540 | HMG_CoA_synt_C | Hydroxymethylglutaryl-coenzyme A synthase C terminal | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR010122 | Family | Hydroxymethylglutaryl-CoA synthase, eukaryotic | Interproscan |
| IPR000590 | Active_site | Hydroxymethylglutaryl-coenzyme A synthase, active site | Interproscan |
| IPR013528 | Domain | Hydroxymethylglutaryl-coenzyme A synthase, N-terminal | Interproscan |
| IPR013746 | Domain | Hydroxymethylglutaryl-coenzyme A synthase, C-terminal domain | Interproscan |
| IPR016039 | Homologous_superfamily | Thiolase-like | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR43323 | 3-HYDROXY-3-METHYLGLUTARYL COENZYME A SYNTHASE | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0004421 | Molecular Function | hydroxymethylglutaryl-CoA synthase activity | Interproscan |
| GO:0008299 | Biological Process | isoprenoid biosynthetic process | Interproscan |
| GO:0006084 | Biological Process | acetyl-CoA metabolic process | Interproscan |
| GO:0010142 | Biological Process | farnesyl diphosphate biosynthetic process, mevalonate pathway | Interproscan |
| GO:0016746 | Molecular Function | acyltransferase activity | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K01641 | HMGCS; hydroxymethylglutaryl-CoA synthase | EC:2.3.3.10 | PPAR signaling pathway | ko03320 | deepkoala |