Genomic Location: chr11:9413275...9427674
NR annotation: XP_031556337.1, transmembrane prolyl 4-hydroxylase-like [Actinia tenebrosa]
| CDS | |||||
| evm.model.ptg000031l.64 | |||||
| Transcript |
| evm.model.ptg000031l.64 |
| Protein |
| evm.model.ptg000031l.64 |
| Uniprot term | Description |
|---|---|
| Q8BG58 | Transmembrane prolyl 4-hydroxylase OS=Mus musculus OX=10090 GN=P4htm PE=1 SV=1 |
| Q9NXG6 | Transmembrane prolyl 4-hydroxylase OS=Homo sapiens OX=9606 GN=P4HTM PE=1 SV=2 |
| Q24JN5 | Prolyl 4-hydroxylase 5 OS=Arabidopsis thaliana OX=3702 GN=P4H5 PE=2 SV=1 |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF13640 | 2OG-FeII_Oxy_3 | 2OG-Fe(II) oxygenase superfamily | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR005123 | Domain | Oxoglutarate/iron-dependent dioxygenase | Interproscan |
| IPR018247 | Binding_site | EF-Hand 1, calcium-binding site | Interproscan |
| IPR045054 | Family | Prolyl 4-hydroxylase | Interproscan |
| IPR002048 | Domain | EF-hand domain | Interproscan |
| IPR006620 | Domain | Prolyl 4-hydroxylase, alpha subunit | Interproscan |
| IPR011992 | Homologous_superfamily | EF-hand domain pair | Interproscan |
| IPR044862 | Domain | Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR10869 | PROLYL 4-HYDROXYLASE ALPHA SUBUNIT | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0004656 | Molecular Function | procollagen-proline 4-dioxygenase activity | Interproscan |
| GO:0005783 | Cellular Component | endoplasmic reticulum | Interproscan |
| GO:0018401 | Biological Process | peptidyl-proline hydroxylation to 4-hydroxy-L-proline | Interproscan |
| GO:0005509 | Molecular Function | calcium ion binding | Interproscan |
| GO:0005506 | Molecular Function | iron ion binding | Interproscan |
| GO:0016705 | Molecular Function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | Interproscan |
| GO:0031418 | Molecular Function | L-ascorbic acid binding | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K06711 | PH-4; hypoxia-inducible factor prolyl 4-hydroxylase | EC:1.14.11.- | Domain-containing proteins not elsewhere classified | ko04990 | deepkoala |