Genomic Location: chr15:18895407...19014437
NR annotation: XP_047133014.1, paired amphipathic helix protein Sin3a-like [Hydra vulgaris]
| CDS | |||||
| evm.model.ptg000037l.47 | |||||
| Transcript |
| evm.model.ptg000037l.47 |
| Protein |
| evm.model.ptg000037l.47 |
| Uniprot term | Description | ||||
|---|---|---|---|---|---|
| Q96ST3 | Paired amphipathic helix protein Sin3a OS=Homo sapiens OX=9606 GN=SIN3A PE=1 SV=2 | ||||
| Q60520 | Paired amphipathic helix protein Sin3a OS=Mus musculus OX=10090 GN=Sin3a PE=1 SV=3 | ||||
| Q62141 | Paired amphipathic helix protein Sin3b OS=Mus musculus OX=10090 GN=Sin3b PE=1 SV=2 |
| Gene family | Subfamily |
|---|---|
| Transcription Factors Family | bHLH |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF00010 | HLH | Helix-loop-helix DNA-binding domain | Domain | Interproscan |
| PF02671 | PAH | Paired amphipathic helix repeat | Repeat | Interproscan |
| PF16879 | Sin3a_C | C-terminal domain of Sin3a protein | Family | Interproscan |
| PF08295 | Sin3_corepress | Sin3 family co-repressor | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR013194 | Domain | Histone deacetylase interacting domain | Interproscan |
| IPR003822 | Repeat | Paired amphipathic helix | Interproscan |
| IPR036638 | Homologous_superfamily | Helix-loop-helix DNA-binding domain superfamily | Interproscan |
| IPR036600 | Homologous_superfamily | Paired amphipathic helix superfamily | Interproscan |
| IPR011598 | Domain | Myc-type, basic helix-loop-helix (bHLH) domain | Interproscan |
| IPR031693 | Domain | Sin3, C-terminal | Interproscan |
| IPR039774 | Family | Transcriptional regulatory protein Sin3-like | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR12346 | SIN3B-RELATED | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0006355 | Biological Process | regulation of DNA-templated transcription | Interproscan |
| GO:0046983 | Molecular Function | protein dimerization activity | Interproscan |
| GO:0000118 | Cellular Component | histone deacetylase complex | Interproscan |
| GO:0000122 | Biological Process | negative regulation of transcription by RNA polymerase II | Interproscan |
| GO:0000785 | Cellular Component | chromatin | Interproscan |
| GO:0003714 | Molecular Function | transcription corepressor activity | Interproscan |
| GO:0016580 | Cellular Component | obsolete Sin3 complex | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K11644 | SIN3A; paired amphipathic helix protein Sin3a | - | Chromosome and associated proteins | ko03036 | deepkoala |
Maintained by Dr. Jiajie She from Prof. Longjun Wu's Lab & Prof. Pei-yuan Qian's Lab
Hong Kong Branch of the Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou)
Hong Kong University of Science and Technology
Clear Water Bay, Kowloon, Hong Kong
© 2026 All Rights Reserved.
