Genomic Location: :...
NR annotation: XP_002423116.1, protein JTB precursor, putative [Pediculus humanus corporis]
| CDS | |||||
| Transcript |
| Protein |
| Uniprot term | Description |
|---|---|
| O70279 | Splicing factor ESS-2 homolog OS=Mus musculus OX=10090 GN=Ess2 PE=1 SV=2 |
| Q96DF8 | Splicing factor ESS-2 homolog OS=Homo sapiens OX=9606 GN=ESS2 PE=1 SV=1 |
| O44424 | Splicing factor ESS-2 homolog OS=Drosophila melanogaster OX=7227 GN=Es2 PE=1 SV=2 |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF05439 | JTB | Jumping translocation breakpoint protein (JTB) | Family | Interproscan |
| PF00616 | RasGAP | GTPase-activator protein for Ras-like GTPase | Family | Interproscan |
| PF18151 | DUF5601 | Domain of unknown function (DUF5601) | Domain | Interproscan |
| PF02204 | VPS9 | Vacuolar sorting protein 9 (VPS9) domain | Family | Interproscan |
| PF09751 | Es2 | Nuclear protein Es2 | Family | Interproscan |
| PF00069 | Pkinase | Protein kinase domain | Domain | Interproscan |
| PF00004 | AAA | ATPase family associated with various cellular activities (AAA) | Domain | Interproscan |
| PF16450 | Prot_ATP_ID_OB_C | Proteasomal ATPase OB C-terminal domain | Domain | Interproscan |
| PF17862 | AAA_lid_3 | AAA+ lid domain | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR036691 | Homologous_superfamily | Endonuclease/exonuclease/phosphatase superfamily | Interproscan |
| IPR008657 | Family | Jumping translocation breakpoint | Interproscan |
| IPR001936 | Domain | Ras GTPase-activating domain | Interproscan |
| IPR037191 | Homologous_superfamily | VPS9 domain superfamily | Interproscan |
| IPR003123 | Domain | VPS9 domain | Interproscan |
| IPR045046 | Family | Vacuolar protein sorting-associated protein 9-like | Interproscan |
| IPR008936 | Homologous_superfamily | Rho GTPase activation protein | Interproscan |
| IPR041545 | Domain | RABX5, catalytic core helical domain | Interproscan |
| IPR019148 | Family | Nuclear protein DGCR14/ESS-2 | Interproscan |
| IPR000719 | Domain | Protein kinase domain | Interproscan |
| IPR017441 | Binding_site | Protein kinase, ATP binding site | Interproscan |
| IPR011009 | Homologous_superfamily | Protein kinase-like domain superfamily | Interproscan |
| IPR008271 | Active_site | Serine/threonine-protein kinase, active site | Interproscan |
| IPR012340 | Homologous_superfamily | Nucleic acid-binding, OB-fold | Interproscan |
| IPR050221 | Family | 26S Proteasome Regulatory ATPase | Interproscan |
| IPR003959 | Domain | ATPase, AAA-type, core | Interproscan |
| IPR046347 | Homologous_superfamily | Basic-leucine zipper domain superfamily | Interproscan |
| IPR003960 | Conserved_site | ATPase, AAA-type, conserved site | Interproscan |
| IPR003593 | Domain | AAA+ ATPase domain | Interproscan |
| IPR027417 | Homologous_superfamily | P-loop containing nucleoside triphosphate hydrolase | Interproscan |
| IPR032501 | Domain | Proteasomal ATPase, second OB domain | Interproscan |
| IPR041569 | Domain | AAA ATPase, AAA+ lid domain | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR46670 | ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN | Interproscan |
| PTHR13041 | JTB PROTEIN-RELATED | Interproscan |
| PTHR23101 | RAB GDP/GTP EXCHANGE FACTOR | Interproscan |
| PTHR12940 | ES-2 PROTEIN - RELATED | Interproscan |
| PTHR24342 | SERINE/THREONINE-PROTEIN KINASE 17 | Interproscan |
| PTHR23073 | 26S PROTEASOME REGULATORY SUBUNIT | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0016020 | Cellular Component | membrane | Interproscan |
| GO:0000281 | Biological Process | mitotic cytokinesis | Interproscan |
| GO:0005737 | Cellular Component | cytoplasm | Interproscan |
| GO:0005813 | Cellular Component | centrosome | Interproscan |
| GO:0005819 | Cellular Component | spindle | Interproscan |
| GO:0030496 | Cellular Component | midbody | Interproscan |
| GO:0043087 | Biological Process | regulation of GTPase activity | Interproscan |
| GO:0005085 | Molecular Function | guanyl-nucleotide exchange factor activity | Interproscan |
| GO:0005829 | Cellular Component | cytosol | Interproscan |
| GO:0016192 | Biological Process | vesicle-mediated transport | Interproscan |
| GO:0030139 | Cellular Component | endocytic vesicle | Interproscan |
| GO:0031267 | Molecular Function | small GTPase binding | Interproscan |
| GO:0071013 | Cellular Component | catalytic step 2 spliceosome | Interproscan |
| GO:0004672 | Molecular Function | protein kinase activity | Interproscan |
| GO:0005524 | Molecular Function | ATP binding | Interproscan |
| GO:0006468 | Biological Process | protein phosphorylation | Interproscan |
| GO:0004674 | Molecular Function | protein serine/threonine kinase activity | Interproscan |
| GO:0005634 | Cellular Component | nucleus | Interproscan |
| GO:0035556 | Biological Process | intracellular signal transduction | Interproscan |
| GO:0043065 | Biological Process | positive regulation of apoptotic process | Interproscan |
| GO:0008540 | Cellular Component | proteasome regulatory particle, base subcomplex | Interproscan |
| GO:0036402 | Molecular Function | proteasome-activating activity | Interproscan |
| GO:0043161 | Biological Process | proteasome-mediated ubiquitin-dependent protein catabolic process | Interproscan |
| GO:0016887 | Molecular Function | ATP hydrolysis activity | Interproscan |
| GO:0003700 | Molecular Function | DNA-binding transcription factor activity | Interproscan |
| GO:0006355 | Biological Process | regulation of DNA-templated transcription | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K03066 | PSMC5, RPT6; 26S proteasome regulatory subunit T6 | - | Membrane trafficking | ko04131 | deepkoala |
| Proteasome | ko03051 | deepkoala |