Genomic Location: :...
NR annotation: XP_047140440.1, ras-specific guanine nucleotide-releasing factor 1-like isoform X2 [Hydra vulgaris]
| CDS | |||||
| Transcript |
| Protein |
| Uniprot term | Description |
|---|---|
| Q13972 | Ras-specific guanine nucleotide-releasing factor 1 OS=Homo sapiens OX=9606 GN=RASGRF1 PE=1 SV=2 |
| A2CEA7 | Ras-specific guanine nucleotide-releasing factor 2 OS=Danio rerio OX=7955 GN=rasgrf2 PE=3 SV=1 |
| P28818 | Ras-specific guanine nucleotide-releasing factor 1 OS=Rattus norvegicus OX=10116 GN=Rasgrf1 PE=1 SV=1 |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF01549 | ShK | ShK domain-like | Domain | Interproscan |
| PF07648 | Kazal_2 | Kazal-type serine protease inhibitor domain | Domain | Interproscan |
| PF09607 | BrkDBD | Brinker DNA-binding domain | Domain | Interproscan |
| PF03221 | HTH_Tnp_Tc5 | Tc5 transposase DNA-binding domain | Domain | Interproscan |
| PF01494 | FAD_binding_3 | FAD binding domain | Family | Interproscan |
| PF00307 | CH | Calponin homology (CH) domain | Domain | Interproscan |
| PF00248 | Aldo_ket_red | Aldo/keto reductase family | Domain | Interproscan |
| PF00078 | RVT_1 | Reverse transcriptase (RNA-dependent DNA polymerase) | Domain | Interproscan |
| PF12783 | Sec7-like_HUS | Mon2/Sec7/BIG1-like, HUS domain | Domain | Interproscan |
| PF01369 | Sec7 | Sec7 domain | Domain | Interproscan |
| PF00169 | PH | PH domain | Domain | Interproscan |
| PF00732 | GMC_oxred_N | GMC oxidoreductase | Domain | Interproscan |
| PF05199 | GMC_oxred_C | GMC oxidoreductase | Domain | Interproscan |
| PF00665 | rve | Integrase core domain | Domain | Interproscan |
| PF00147 | Fibrinogen_C | Fibrinogen beta and gamma chains, C-terminal globular domain | Domain | Interproscan |
| PF00618 | RasGEF_N | RasGEF N-terminal motif | Domain | Interproscan |
| PF00621 | RhoGEF | RhoGEF domain | Domain | Interproscan |
| PF00617 | RasGEF | RasGEF domain | Family | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR003582 | Domain | ShKT domain | Interproscan |
| IPR036058 | Homologous_superfamily | Kazal domain superfamily | Interproscan |
| IPR002350 | Domain | Kazal domain | Interproscan |
| IPR018586 | Domain | Brinker DNA-binding domain | Interproscan |
| IPR006600 | Domain | HTH CenpB-type DNA-binding domain | Interproscan |
| IPR010921 | Homologous_superfamily | Trp repressor/replication initiator | Interproscan |
| IPR009057 | Homologous_superfamily | Homeobox-like domain superfamily | Interproscan |
| IPR036872 | Homologous_superfamily | CH domain superfamily | Interproscan |
| IPR036188 | Homologous_superfamily | FAD/NAD(P)-binding domain superfamily | Interproscan |
| IPR002938 | Domain | FAD-binding domain | Interproscan |
| IPR001715 | Domain | Calponin homology domain | Interproscan |
| IPR050540 | Family | F-actin Monooxygenase Mical | Interproscan |
| IPR020471 | Family | Aldo-keto reductase | Interproscan |
| IPR036812 | Homologous_superfamily | NADP-dependent oxidoreductase domain superfamily | Interproscan |
| IPR018170 | Conserved_site | Aldo/keto reductase, conserved site | Interproscan |
| IPR023210 | Domain | NADP-dependent oxidoreductase domain | Interproscan |
| IPR000477 | Domain | Reverse transcriptase domain | Interproscan |
| IPR043502 | Homologous_superfamily | DNA/RNA polymerase superfamily | Interproscan |
| IPR043128 | Homologous_superfamily | Reverse transcriptase/Diguanylate cyclase domain | Interproscan |
| IPR000904 | Domain | Sec7 domain | Interproscan |
| IPR035999 | Homologous_superfamily | Sec7 domain superfamily | Interproscan |
| IPR032691 | Domain | Mon2/Sec7/BIG1-like, HUS domain | Interproscan |
| IPR023394 | Homologous_superfamily | Sec7, C-terminal domain superfamily | Interproscan |
| IPR011993 | Homologous_superfamily | PH-like domain superfamily | Interproscan |
| IPR001849 | Domain | Pleckstrin homology domain | Interproscan |
| IPR045188 | Family | PH domain containing protein Boi1/Boi2-like | Interproscan |
| IPR052542 | Family | Cholesterol Oxidase Enzyme | Interproscan |
| IPR000172 | Domain | Glucose-methanol-choline oxidoreductase, N-terminal | Interproscan |
| IPR007867 | Domain | Glucose-methanol-choline oxidoreductase, C-terminal | Interproscan |
| IPR029058 | Homologous_superfamily | Alpha/Beta hydrolase fold | Interproscan |
| IPR050951 | Family | Retrovirus-related Pol polyprotein | Interproscan |
| IPR001584 | Domain | Integrase, catalytic core | Interproscan |
| IPR012337 | Homologous_superfamily | Ribonuclease H-like superfamily | Interproscan |
| IPR036397 | Homologous_superfamily | Ribonuclease H superfamily | Interproscan |
| IPR018247 | Binding_site | EF-Hand 1, calcium-binding site | Interproscan |
| IPR003299 | Family | Flagellar calcium-binding protein calflagin | Interproscan |
| IPR002048 | Domain | EF-hand domain | Interproscan |
| IPR011992 | Homologous_superfamily | EF-hand domain pair | Interproscan |
| IPR002181 | Domain | Fibrinogen, alpha/beta/gamma chain, C-terminal globular domain | Interproscan |
| IPR050373 | Family | Fibrinogen C-terminal domain-containing protein | Interproscan |
| IPR036056 | Homologous_superfamily | Fibrinogen-like, C-terminal | Interproscan |
| IPR014716 | Homologous_superfamily | Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1 | Interproscan |
| IPR001895 | Domain | Ras guanine-nucleotide exchange factors catalytic domain | Interproscan |
| IPR023578 | Homologous_superfamily | Ras guanine nucleotide exchange factor domain superfamily | Interproscan |
| IPR008937 | Family | Ras-like guanine nucleotide exchange factor | Interproscan |
| IPR019804 | Conserved_site | Ras guanine-nucleotide exchange factor, conserved site | Interproscan |
| IPR035899 | Homologous_superfamily | Dbl homology (DH) domain superfamily | Interproscan |
| IPR000219 | Domain | Dbl homology (DH) domain | Interproscan |
| IPR000651 | Domain | Ras-like guanine nucleotide exchange factor, N-terminal | Interproscan |
| IPR036964 | Homologous_superfamily | Ras guanine-nucleotide exchange factor, catalytic domain superfamily | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR23167 | CALPONIN HOMOLOGY DOMAIN-CONTAINING PROTEIN DDB_G0272472-RELATED | Interproscan |
| PTHR11732 | ALDO/KETO REDUCTASE | Interproscan |
| PTHR47331 | PHD-TYPE DOMAIN-CONTAINING PROTEIN | Interproscan |
| PTHR10663 | GUANYL-NUCLEOTIDE EXCHANGE FACTOR | Interproscan |
| PTHR22902 | SESQUIPEDALIAN | Interproscan |
| PTHR47470 | CHOLESTEROL OXIDASE | Interproscan |
| PTHR37984 | PROTEIN CBG26694 | Interproscan |
| PTHR19143 | FIBRINOGEN/TENASCIN/ANGIOPOEITIN | Interproscan |
| PTHR23113 | GUANINE NUCLEOTIDE EXCHANGE FACTOR | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0005515 | Molecular Function | protein binding | Interproscan |
| GO:0043565 | Molecular Function | sequence-specific DNA binding | Interproscan |
| GO:0071949 | Molecular Function | FAD binding | Interproscan |
| GO:0004032 | Molecular Function | aldose reductase (NADPH) activity | Interproscan |
| GO:0005829 | Cellular Component | cytosol | Interproscan |
| GO:0016491 | Molecular Function | oxidoreductase activity | Interproscan |
| GO:0005085 | Molecular Function | guanyl-nucleotide exchange factor activity | Interproscan |
| GO:0032012 | Biological Process | regulation of ARF protein signal transduction | Interproscan |
| GO:0001881 | Biological Process | receptor recycling | Interproscan |
| GO:0005769 | Cellular Component | early endosome | Interproscan |
| GO:0005802 | Cellular Component | trans-Golgi network | Interproscan |
| GO:0007032 | Biological Process | endosome organization | Interproscan |
| GO:0042147 | Biological Process | retrograde transport, endosome to Golgi | Interproscan |
| GO:0055037 | Cellular Component | recycling endosome | Interproscan |
| GO:0016614 | Molecular Function | oxidoreductase activity, acting on CH-OH group of donors | Interproscan |
| GO:0050660 | Molecular Function | flavin adenine dinucleotide binding | Interproscan |
| GO:0015074 | Biological Process | DNA integration | Interproscan |
| GO:0003676 | Molecular Function | nucleic acid binding | Interproscan |
| GO:0005509 | Molecular Function | calcium ion binding | Interproscan |
| GO:0005615 | Cellular Component | extracellular space | Interproscan |
| GO:0062023 | Cellular Component | collagen-containing extracellular matrix | Interproscan |
| GO:0007264 | Biological Process | small GTPase-mediated signal transduction | Interproscan |
| GO:0005886 | Cellular Component | plasma membrane | Interproscan |
| GO:0007265 | Biological Process | Ras protein signal transduction | Interproscan |
| GO:0043547 | Biological Process | positive regulation of GTPase activity | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K23791 | PHETA; sesquipedalian | - | Focal adhesion | ko04510 | deepkoala |
| Membrane trafficking | ko04131 | deepkoala | |||
| Membrane trafficking | ko04131 | deepkoala |