Genomic Location: Sc0000012:775889...788449
NR annotation: XP_029179659.2, cytochrome P450 27C1-like [Acropora millepora]
Species Montipora capitata · all data for this species · gene families
| CDS |
| g1084.t1 |
| Transcript |
| g1084.t1 |
| Protein |
| g1084.t1 |
| UniProt accession | Description |
|---|---|
| Q4G0S4 | Cytochrome P450 27C1 OS=Homo sapiens OX=9606 GN=CYP27C1 PE=1 SV=3 |
| P17178 | Sterol 26-hydroxylase, mitochondrial OS=Rattus norvegicus OX=10116 GN=Cyp27a1 PE=1 SV=1 |
| P0DOX0 | Cytochrome P450 27C1 OS=Aquarana catesbeiana OX=8400 GN=cyp27c1 PE=1 SV=1 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0000338 (this species only) · gene tree & orthology |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF00067 all species → | p450 | Cytochrome P450 | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR001128 all species → | Family | Cytochrome P450 | Interproscan |
| IPR036396 all species → | Homologous_superfamily | Cytochrome P450 superfamily | Interproscan |
| IPR017972 all species → | Conserved_site | Cytochrome P450, conserved site | Interproscan |
| IPR002401 all species → | Family | Cytochrome P450, E-class, group I | Interproscan |
| IPR050479 all species → | Family | Cytochrome P450, families 11 and 27 | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR24279 all species → | - | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0004497 all species → | Molecular Function | monooxygenase activity | Interproscan |
| GO:0005506 all species → | Molecular Function | iron ion binding | Interproscan |
| GO:0016705 all species → | Molecular Function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | Interproscan |
| GO:0020037 all species → | Molecular Function | heme binding | Interproscan |
| GO:0005743 all species → | Cellular Component | mitochondrial inner membrane | Interproscan |
| GO:0006700 all species → | Biological Process | C21-steroid hormone biosynthetic process | Interproscan |
| GO:0006704 all species → | Biological Process | glucocorticoid biosynthetic process | Interproscan |
| GO:0008203 all species → | Biological Process | cholesterol metabolic process | Interproscan |
| GO:0034650 all species → | Biological Process | cortisol metabolic process | Interproscan |
| GO:0071375 all species → | Biological Process | cellular response to peptide hormone stimulus | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K17951 | CYP27C1; all-trans-retinol 3,4-desaturase | EC:1.14.19.53 | Cytochrome P450 | ko00199 | deepkoala |
Transcript abundance of g1084.t1 across 48 RNA-seq samples of Montipora capitata. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.
| Condition | Samples | TPM > 0 | Mean TPM | Max TPM | Mean, relative to max |
|---|---|---|---|---|---|
| whole organisms · ambient pH treatment | 21 | 13 | 7.29 | 44.03 | |
| whole organisms · low pH treatment | 15 | 11 | 6.89 | 28.28 | |
| whole organisms · extra low pH treatment pH treatment | 12 | 8 | 9.22 | 37.07 |
| SRA run | Condition | Tissue | Developmental stage | Treatment | Study | TPM |
|---|---|---|---|---|---|---|
| SRR11452230 | whole organisms · ambient pH treatment | whole organisms | planulae | ambient pH treatment | SRP254626 | 44.03 |
| SRR11452222 | whole organisms · ambient pH treatment | whole organisms | planulae | ambient pH treatment | SRP254626 | 40.12 |
| SRR11452228 | whole organisms · ambient pH treatment | whole organisms | planulae | ambient pH treatment | SRP254626 | 27.53 |
| SRR11452232 | whole organisms · ambient pH treatment | whole organisms | blastula | ambient pH treatment | SRP254626 | 8.52 |
| SRR11452231 | whole organisms · ambient pH treatment | whole organisms | blastula | ambient pH treatment | SRP254626 | 7.46 |
| SRR11452234 | whole organisms · ambient pH treatment | whole organisms | morula | ambient pH treatment | SRP254626 | 4.55 |
| SRR11452237 | whole organisms · ambient pH treatment | whole organisms | gastrula | ambient pH treatment | SRP254626 | 4.23 |
| SRR11452252 | whole organisms · ambient pH treatment | whole organisms | prawn chip | ambient pH treatment | SRP254626 | 4.09 |
| SRR11452243 | whole organisms · ambient pH treatment | whole organisms | gastrula | ambient pH treatment | SRP254626 | 3.62 |
| SRR11452246 | whole organisms · ambient pH treatment | whole organisms | prawn chip | ambient pH treatment | SRP254626 | 2.94 |
| SRR11452250 | whole organisms · ambient pH treatment | whole organisms | prawn chip | ambient pH treatment | SRP254626 | 2.75 |
| SRR11452242 | whole organisms · ambient pH treatment | whole organisms | gastrula | ambient pH treatment | SRP254626 | 1.88 |
| SRR11452263 | whole organisms · ambient pH treatment | whole organisms | egg | ambient pH treatment | SRP254626 | 1.35 |
| SRR11452217 | whole organisms · ambient pH treatment | whole organisms | fertilized embryo | ambient pH treatment | SRP254626 | 0.00 |
| SRR11452233 | whole organisms · ambient pH treatment | whole organisms | morula | ambient pH treatment | SRP254626 | 0.00 |
| SRR11452240 | whole organisms · ambient pH treatment | whole organisms | fertilized embryo | ambient pH treatment | SRP254626 | 0.00 |
| SRR11452251 | whole organisms · ambient pH treatment | whole organisms | egg | ambient pH treatment | SRP254626 | 0.00 |
| SRR11452254 | whole organisms · ambient pH treatment | whole organisms | cleavage | ambient pH treatment | SRP254626 | 0.00 |
| SRR11452259 | whole organisms · ambient pH treatment | whole organisms | cleavage | ambient pH treatment | SRP254626 | 0.00 |
| SRR11452260 | whole organisms · ambient pH treatment | whole organisms | cleavage | ambient pH treatment | SRP254626 | 0.00 |
| SRR11452262 | whole organisms · ambient pH treatment | whole organisms | egg | ambient pH treatment | SRP254626 | 0.00 |
| SRR11452223 | whole organisms · low pH treatment | whole organisms | planulae | low pH treatment | SRP254626 | 28.28 |
| SRR11452224 | whole organisms · low pH treatment | whole organisms | planulae | low pH treatment | SRP254626 | 27.90 |
| SRR11452221 | whole organisms · low pH treatment | whole organisms | planulae | low pH treatment | SRP254626 | 26.59 |
| SRR11452247 | whole organisms · low pH treatment | whole organisms | prawn chip | low pH treatment | SRP254626 | 4.55 |
| SRR11452245 | whole organisms · low pH treatment | whole organisms | prawn chip | low pH treatment | SRP254626 | 2.92 |
| SRR11452258 | whole organisms · low pH treatment | whole organisms | cleavage | low pH treatment | SRP254626 | 2.70 |
| SRR11452241 | whole organisms · low pH treatment | whole organisms | gastrula | low pH treatment | SRP254626 | 2.44 |
| SRR11452218 | whole organisms · low pH treatment | whole organisms | fertilized embryo | low pH treatment | SRP254626 | 2.19 |
| SRR11452238 | whole organisms · low pH treatment | whole organisms | gastrula | low pH treatment | SRP254626 | 2.08 |
| SRR11452236 | whole organisms · low pH treatment | whole organisms | gastrula | low pH treatment | SRP254626 | 2.07 |
| SRR11452249 | whole organisms · low pH treatment | whole organisms | prawn chip | low pH treatment | SRP254626 | 1.61 |
| SRR11452216 | whole organisms · low pH treatment | whole organisms | fertilized embryo | low pH treatment | SRP254626 | 0.00 |
| SRR11452229 | whole organisms · low pH treatment | whole organisms | fertilized embryo | low pH treatment | SRP254626 | 0.00 |
| SRR11452253 | whole organisms · low pH treatment | whole organisms | cleavage | low pH treatment | SRP254626 | 0.00 |
| SRR11452255 | whole organisms · low pH treatment | whole organisms | cleavage | low pH treatment | SRP254626 | 0.00 |
| SRR11452227 | whole organisms · extra low pH treatment pH treatment | whole organisms | planulae | extra low pH treatment pH treatment | SRP254626 | 37.07 |
| SRR11452226 | whole organisms · extra low pH treatment pH treatment | whole organisms | planulae | extra low pH treatment pH treatment | SRP254626 | 32.28 |
| SRR11452225 | whole organisms · extra low pH treatment pH treatment | whole organisms | planulae | extra low pH treatment pH treatment | SRP254626 | 28.36 |
| SRR11452248 | whole organisms · extra low pH treatment pH treatment | whole organisms | prawn chip | extra low pH treatment pH treatment | SRP254626 | 4.60 |
| SRR11452244 | whole organisms · extra low pH treatment pH treatment | whole organisms | prawn chip | extra low pH treatment pH treatment | SRP254626 | 3.01 |
| SRR11452239 | whole organisms · extra low pH treatment pH treatment | whole organisms | gastrula | extra low pH treatment pH treatment | SRP254626 | 2.39 |
| SRR11452235 | whole organisms · extra low pH treatment pH treatment | whole organisms | gastrula | extra low pH treatment pH treatment | SRP254626 | 2.26 |
| SRR11452257 | whole organisms · extra low pH treatment pH treatment | whole organisms | cleavage | extra low pH treatment pH treatment | SRP254626 | 0.67 |
| SRR11452219 | whole organisms · extra low pH treatment pH treatment | whole organisms | fertilized embryo | extra low pH treatment pH treatment | SRP254626 | 0.00 |
| SRR11452220 | whole organisms · extra low pH treatment pH treatment | whole organisms | fertilized embryo | extra low pH treatment pH treatment | SRP254626 | 0.00 |
| SRR11452256 | whole organisms · extra low pH treatment pH treatment | whole organisms | cleavage | extra low pH treatment pH treatment | SRP254626 | 0.00 |
| SRR11452261 | whole organisms · extra low pH treatment pH treatment | whole organisms | fertilized embryo | extra low pH treatment pH treatment | SRP254626 | 0.00 |
Source: CnidoSite RNA-seq expression matrices (MCAPI_TPM,
StringTie quantification over 48 runs), joined to SRA sample
metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped
by the descriptor carried in the expression matrix itself.
Genes whose expression across the transcriptome samples of Montipora capitata tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.
| Direction | Partners | Most correlated partner | PCC |
|---|---|---|---|
| Positively correlated | 22 | g12097.t1 | 0.988055840947 |
| Negatively correlated | 3 | g19376.t1 | -0.895484613152097 |
Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list.
Whether this gene can be visualised in the single-cell atlases of Montipora capitata, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.
No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.
Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.
No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.
Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.
| Analysis | What it does | Status | |
|---|---|---|---|
| Primer design | Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed. | template found | open → |
| BLAST | Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start. | template found | open → |
| Expression heatmap | Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it. | ready | open → |
| Gene family / orthogroup | Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue. | open → | |
| Gene set analysis | Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it. | open → |