Genomic Location: chr5Alt:9116694...9148150
NR annotation: XP_029179721.2, ATP-dependent DNA helicase DDX11-like [Acropora millepora]
Species Acropora digitifera · all data for this species · gene families
| CDS |
| g10871.t1 |
| Transcript |
| chr5Alt.g10871.t1 |
| Protein |
| chr5Alt.g10871.t1 |
| UniProt accession | Description |
|---|---|
| Q6AXC6 | ATP-dependent DNA helicase DDX11 OS=Mus musculus OX=10090 GN=Ddx11 PE=1 SV=2 |
| F1R345 | ATP-dependent DNA helicase DDX11 OS=Danio rerio OX=7955 GN=ddx11 PE=2 SV=1 |
| A8MPP1 | Putative ATP-dependent DNA helicase DDX11-like protein 8 OS=Homo sapiens OX=9606 GN=DDX11L8 PE=1 SV=1 |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF06733 all species → | DEAD_2 | DEAD_2 | Family | Interproscan |
| PF13307 all species → | Helicase_C_2 | Helicase C-terminal domain | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR006554 all species → | Domain | Helicase-like, DEXD box c2 type | Interproscan |
| IPR014013 all species → | Domain | Helicase superfamily 1/2, ATP-binding domain, DinG/Rad3-type | Interproscan |
| IPR010614 all species → | Domain | RAD3-like helicase, DEAD | Interproscan |
| IPR006555 all species → | Domain | ATP-dependent helicase, C-terminal | Interproscan |
| IPR027417 all species → | Homologous_superfamily | P-loop containing nucleoside triphosphate hydrolase | Interproscan |
| IPR013020 all species → | Family | ATP-dependent helicase Rad3/Chl1-like | Interproscan |
| IPR045028 all species → | Family | Helicase superfamily 1/2, DinG/Rad3-like | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR11472 all species → | DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0003678 all species → | Molecular Function | DNA helicase activity | Interproscan |
| GO:0016818 all species → | Molecular Function | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | Interproscan |
| GO:0005524 all species → | Molecular Function | ATP binding | Interproscan |
| GO:0003677 all species → | Molecular Function | DNA binding | Interproscan |
| GO:0003676 all species → | Molecular Function | nucleic acid binding | Interproscan |
| GO:0004386 all species → | Molecular Function | helicase activity | Interproscan |
| GO:0006139 all species → | Biological Process | nucleobase-containing compound metabolic process | Interproscan |
| GO:0005634 all species → | Cellular Component | nucleus | Interproscan |
| GO:0032508 all species → | Biological Process | DNA duplex unwinding | Interproscan |
| GO:0034085 all species → | Biological Process | establishment of sister chromatid cohesion | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K11273 | DDX11, CHL1, CTF1; chromosome transmission fidelity protein 1 | EC:5.6.2.7 | Chromosome and associated proteins | ko03036 | deepkoala |
Transcript abundance of g10871.t1 across 39 RNA-seq samples of Acropora digitifera. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.
| Condition | Samples | TPM > 0 | Mean TPM | Max TPM | Mean, relative to max |
|---|---|---|---|---|---|
| Coral branch | 39 | 39 | 9.24 | 14.00 |
| SRA run | Condition | Tissue | Developmental stage | Treatment | Study | TPM |
|---|---|---|---|---|---|---|
| SRR23047208 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 14.00 |
| SRR23047210 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 13.46 |
| SRR23047209 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 13.30 |
| SRR23047240 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 12.68 |
| SRR23047233 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 12.33 |
| SRR23047221 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 12.02 |
| SRR23047206 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 11.64 |
| SRR23047242 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 11.49 |
| SRR23047238 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 10.76 |
| SRR23047239 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 10.63 |
| SRR23047229 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 10.48 |
| SRR23047214 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 10.37 |
| SRR23047231 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 10.15 |
| SRR23047232 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 10.05 |
| SRR23047213 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 9.84 |
| SRR23047216 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 9.39 |
| SRR23047215 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 9.26 |
| SRR23047241 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 8.89 |
| SRR23047243 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 8.81 |
| SRR23047234 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 8.78 |
| SRR23047225 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 8.73 |
| SRR23047227 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 8.70 |
| SRR23047219 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 8.41 |
| SRR23047220 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 8.33 |
| SRR23047228 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 8.25 |
| SRR23047207 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 8.19 |
| SRR23047230 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 8.01 |
| SRR23047223 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 7.92 |
| SRR23047237 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 7.89 |
| SRR23047222 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 7.81 |
| SRR23047226 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 7.62 |
| SRR23047212 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 7.36 |
| SRR23047235 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 6.84 |
| SRR23047224 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 6.72 |
| SRR23047218 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 6.71 |
| SRR23047217 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 6.62 |
| SRR23047211 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 6.59 |
| SRR23047236 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 5.63 |
| SRR23047244 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 5.56 |
Source: CnidoSite RNA-seq expression matrices (ADIGI_TPM,
StringTie quantification over 39 runs), joined to SRA sample
metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped
by the descriptor carried in the expression matrix itself.
Genes whose expression across the transcriptome samples of Acropora digitifera tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.
| Direction | Partners | Most correlated partner | PCC |
|---|---|---|---|
| Positively correlated | 7 | g10321.t1 | 0.730813792104653 |
| Negatively correlated | 16 | g7807.t1 | -0.745221822502701 |
Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list.
Whether this gene can be visualised in the single-cell atlases of Acropora digitifera, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.
No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.
Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.
| Assay | Sample | Peaks | Region |
|---|
No called peak overlaps this gene in 1 available assay. Either the gene is not near an accessible or marked region in those samples, or it is not represented in the peak caller’s annotation.
Browse the full epigenomic landscape of this species: DNase-seq (DHS).
Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.
| Analysis | What it does | Status | |
|---|---|---|---|
| Primer design | Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed. | template found | open → |
| BLAST | Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start. | template found | open → |
| Expression heatmap | Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it. | ready | open → |
| Gene family / orthogroup | Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue. | open → | |
| Gene set analysis | Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it. | open → |