Genomic Location: :...
NR annotation: MBU2643235.1, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [bacterium]
| CDS | |||||
| Transcript |
| Protein |
| Uniprot term | Description | ||||
|---|---|---|---|---|---|
| Q0AYR3 | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase OS=Syntrophomonas wolfei subsp. wolfei (strain DSM 2245B / Goettingen) OX=335541 GN=murE PE=3 SV=1 | ||||
| Q97H84 | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase 1 OS=Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / IAM 19013 / LMG 5710 / NBRC 13948 / NRRL B-527 / VKM B-1787 / 2291 / W) OX=272562 GN=murE1 PE=3 SV=1 | ||||
| Q182Z8 | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase OS=Clostridioides difficile (strain 630) OX=272563 GN=murE PE=3 SV=1 |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF01168 | Ala_racemase_N | Alanine racemase, N-terminal domain | Domain | Interproscan |
| PF02875 | Mur_ligase_C | Mur ligase family, glutamate ligase domain | Domain | Interproscan |
| PF08245 | Mur_ligase_M | Mur ligase middle domain | Domain | Interproscan |
| PF00842 | Ala_racemase_C | Alanine racemase, C-terminal domain | Domain | Interproscan |
| PF00155 | Aminotran_1_2 | Aminotransferase class I and II | Domain | Interproscan |
| PF01979 | Amidohydro_1 | Amidohydrolase family | Domain | Interproscan |
| PF00651 | BTB | BTB/POZ domain | Domain | Interproscan |
| PF07707 | BACK | BTB And C-terminal Kelch | Domain | Interproscan |
| PF01344 | Kelch_1 | Kelch motif | Repeat | Interproscan |
| PF00400 | WD40 | WD domain, G-beta repeat | Repeat | Interproscan |
| PF03109 | ABC1 | ABC1 atypical kinase-like domain | Domain | Interproscan |
| PF08395 | 7tm_7 | 7tm Chemosensory receptor | Family | Interproscan |
| PF00270 | DEAD | DEAD/DEAH box helicase | Domain | Interproscan |
| PF00076 | RRM_1 | RNA recognition motif | Domain | Interproscan |
| PF00098 | zf-CCHC | Zinc knuckle | Domain | Interproscan |
| PF00271 | Helicase_C | Helicase conserved C-terminal domain | Domain | Interproscan |
| PF02277 | DBI_PRT | Phosphoribosyltransferase | Domain | Interproscan |
| PF00488 | MutS_V | MutS domain V | Domain | Interproscan |
| PF05190 | MutS_IV | MutS family domain IV | Domain | Interproscan |
| PF00018 | SH3_1 | SH3 domain | Domain | Interproscan |
| PF00790 | VHS | VHS domain | Repeat | Interproscan |
| PF00520 | Ion_trans | Ion transport protein | Family | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR036565 | Homologous_superfamily | Mur-like, catalytic domain superfamily | Interproscan |
| IPR009006 | Homologous_superfamily | Alanine racemase/group IV decarboxylase, C-terminal | Interproscan |
| IPR036615 | Homologous_superfamily | Mur ligase, C-terminal domain superfamily | Interproscan |
| IPR011079 | Domain | Alanine racemase, C-terminal | Interproscan |
| IPR005761 | Family | UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase | Interproscan |
| IPR000821 | Family | Alanine racemase | Interproscan |
| IPR001608 | Domain | Alanine racemase, N-terminal | Interproscan |
| IPR004101 | Domain | Mur ligase, C-terminal | Interproscan |
| IPR013221 | Domain | Mur ligase, central | Interproscan |
| IPR029066 | Homologous_superfamily | PLP-binding barrel | Interproscan |
| IPR018109 | Conserved_site | Folylpolyglutamate synthetase, conserved site | Interproscan |
| IPR035911 | Homologous_superfamily | MurE/MurF, N-terminal | Interproscan |
| IPR015422 | Homologous_superfamily | Pyridoxal phosphate-dependent transferase, small domain | Interproscan |
| IPR015421 | Homologous_superfamily | Pyridoxal phosphate-dependent transferase, major domain | Interproscan |
| IPR004839 | Domain | Aminotransferase, class I/classII | Interproscan |
| IPR015424 | Homologous_superfamily | Pyridoxal phosphate-dependent transferase | Interproscan |
| IPR050596 | Family | Class-I Pyridoxal-Phosphate-Dependent Aminotransferase | Interproscan |
| IPR051607 | Family | Metallo-dependent Hydrolases | Interproscan |
| IPR011059 | Homologous_superfamily | Metal-dependent hydrolase, composite domain superfamily | Interproscan |
| IPR014311 | Family | Guanine deaminase | Interproscan |
| IPR006680 | Domain | Amidohydrolase-related | Interproscan |
| IPR032466 | Homologous_superfamily | Metal-dependent hydrolase | Interproscan |
| IPR011043 | Homologous_superfamily | Galactose oxidase/kelch, beta-propeller | Interproscan |
| IPR011333 | Homologous_superfamily | SKP1/BTB/POZ domain superfamily | Interproscan |
| IPR000210 | Domain | BTB/POZ domain | Interproscan |
| IPR006652 | Repeat | Kelch repeat type 1 | Interproscan |
| IPR011705 | Domain | BTB/Kelch-associated | Interproscan |
| IPR017096 | Family | BTB-kelch protein | Interproscan |
| IPR015915 | Homologous_superfamily | Kelch-type beta propeller | Interproscan |
| IPR050061 | Family | Peptidoglycan biosynthesis MurCDEF | Interproscan |
| IPR001680 | Repeat | WD40 repeat | Interproscan |
| IPR015943 | Homologous_superfamily | WD40/YVTN repeat-like-containing domain superfamily | Interproscan |
| IPR052596 | Family | Activating Molecule in BECN1-Regulated Autophagy | Interproscan |
| IPR011047 | Homologous_superfamily | Quinoprotein alcohol dehydrogenase-like superfamily | Interproscan |
| IPR034646 | Domain | ADCK3-like domain | Interproscan |
| IPR011009 | Homologous_superfamily | Protein kinase-like domain superfamily | Interproscan |
| IPR004147 | Domain | ABC1 atypical kinase-like domain | Interproscan |
| IPR051409 | Family | Atypical kinase ADCK | Interproscan |
| IPR013604 | Family | 7TM chemosensory receptor | Interproscan |
| IPR011545 | Domain | DEAD/DEAH box helicase domain | Interproscan |
| IPR000504 | Domain | RNA recognition motif domain | Interproscan |
| IPR001650 | Domain | Helicase, C-terminal domain-like | Interproscan |
| IPR012677 | Homologous_superfamily | Nucleotide-binding alpha-beta plait domain superfamily | Interproscan |
| IPR036875 | Homologous_superfamily | Zinc finger, CCHC-type superfamily | Interproscan |
| IPR001878 | Domain | Zinc finger, CCHC-type | Interproscan |
| IPR000629 | Conserved_site | ATP-dependent RNA helicase DEAD-box, conserved site | Interproscan |
| IPR014014 | Domain | RNA helicase, DEAD-box type, Q motif | Interproscan |
| IPR035979 | Homologous_superfamily | RNA-binding domain superfamily | Interproscan |
| IPR014001 | Domain | Helicase superfamily 1/2, ATP-binding domain | Interproscan |
| IPR027417 | Homologous_superfamily | P-loop containing nucleoside triphosphate hydrolase | Interproscan |
| IPR036087 | Homologous_superfamily | Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like superfamily | Interproscan |
| IPR003200 | Family | Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase | Interproscan |
| IPR045076 | Family | DNA mismatch repair MutS family | Interproscan |
| IPR036187 | Homologous_superfamily | DNA mismatch repair protein MutS, core domain superfamily | Interproscan |
| IPR000432 | Domain | DNA mismatch repair protein MutS, C-terminal | Interproscan |
| IPR007861 | Domain | DNA mismatch repair protein MutS, clamp | Interproscan |
| IPR001452 | Domain | SH3 domain | Interproscan |
| IPR002014 | Domain | VHS domain | Interproscan |
| IPR008942 | Homologous_superfamily | ENTH/VHS | Interproscan |
| IPR050670 | Family | Signal Transducing Adapter Molecule | Interproscan |
| IPR036028 | Homologous_superfamily | SH3-like domain superfamily | Interproscan |
| IPR027359 | Homologous_superfamily | Voltage-dependent channel domain superfamily | Interproscan |
| IPR028798 | Family | Two pore channel protein 2 | Interproscan |
| IPR005821 | Domain | Ion transport domain | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR23135 | MUR LIGASE FAMILY MEMBER | Interproscan |
| PTHR46383 | ASPARTATE AMINOTRANSFERASE | Interproscan |
| PTHR11271 | GUANINE DEAMINASE | Interproscan |
| PTHR45632 | LD33804P | Interproscan |
| PTHR43445 | UDP-N-ACETYLMURAMATE--L-ALANINE LIGASE-RELATED | Interproscan |
| PTHR22874 | ACTIVATING MOLECULE IN BECN1-REGULATED AUTOPHAGY PROTEIN 1 | Interproscan |
| PTHR43851 | - | Interproscan |
| PTHR21421 | GUSTATORY RECEPTOR | Interproscan |
| PTHR47958 | ATP-DEPENDENT RNA HELICASE DBP3 | Interproscan |
| PTHR43463 | NICOTINATE-NUCLEOTIDE--DIMETHYLBENZIMIDAZOLE PHOSPHORIBOSYLTRANSFERASE | Interproscan |
| PTHR11361 | DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER | Interproscan |
| PTHR45929 | JAK PATHWAY SIGNAL TRANSDUCTION ADAPTOR MOLECULE | Interproscan |
| PTHR46768 | TWO PORE CALCIUM CHANNEL PROTEIN 2 | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0005524 | Molecular Function | ATP binding | Interproscan |
| GO:0009058 | Biological Process | biosynthetic process | Interproscan |
| GO:0003824 | Molecular Function | catalytic activity | Interproscan |
| GO:0016881 | Molecular Function | acid-amino acid ligase activity | Interproscan |
| GO:0005737 | Cellular Component | cytoplasm | Interproscan |
| GO:0008360 | Biological Process | regulation of cell shape | Interproscan |
| GO:0051301 | Biological Process | cell division | Interproscan |
| GO:0006522 | Biological Process | alanine metabolic process | Interproscan |
| GO:0008784 | Molecular Function | alanine racemase activity | Interproscan |
| GO:0004326 | Molecular Function | tetrahydrofolylpolyglutamate synthase activity | Interproscan |
| GO:0009396 | Biological Process | folic acid-containing compound biosynthetic process | Interproscan |
| GO:0030170 | Molecular Function | pyridoxal phosphate binding | Interproscan |
| GO:0005829 | Cellular Component | cytosol | Interproscan |
| GO:0008270 | Molecular Function | zinc ion binding | Interproscan |
| GO:0008892 | Molecular Function | guanine deaminase activity | Interproscan |
| GO:0019239 | Molecular Function | deaminase activity | Interproscan |
| GO:0046098 | Biological Process | guanine metabolic process | Interproscan |
| GO:0016810 | Molecular Function | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds | Interproscan |
| GO:0006147 | Biological Process | guanine catabolic process | Interproscan |
| GO:0016787 | Molecular Function | hydrolase activity | Interproscan |
| GO:0005515 | Molecular Function | protein binding | Interproscan |
| GO:0006914 | Biological Process | autophagy | Interproscan |
| GO:0043231 | Cellular Component | intracellular membrane-bounded organelle | Interproscan |
| GO:0006744 | Biological Process | ubiquinone biosynthetic process | Interproscan |
| GO:0007606 | Biological Process | sensory perception of chemical stimulus | Interproscan |
| GO:0016020 | Cellular Component | membrane | Interproscan |
| GO:0050909 | Biological Process | sensory perception of taste | Interproscan |
| GO:0003676 | Molecular Function | nucleic acid binding | Interproscan |
| GO:0003723 | Molecular Function | RNA binding | Interproscan |
| GO:0003724 | Molecular Function | RNA helicase activity | Interproscan |
| GO:0005634 | Cellular Component | nucleus | Interproscan |
| GO:0007276 | Biological Process | gamete generation | Interproscan |
| GO:0030154 | Biological Process | cell differentiation | Interproscan |
| GO:0043186 | Cellular Component | P granule | Interproscan |
| GO:0008939 | Molecular Function | nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity | Interproscan |
| GO:0003690 | Molecular Function | double-stranded DNA binding | Interproscan |
| GO:0006298 | Biological Process | mismatch repair | Interproscan |
| GO:0030983 | Molecular Function | mismatched DNA binding | Interproscan |
| GO:0032301 | Cellular Component | MutSalpha complex | Interproscan |
| GO:0140664 | Molecular Function | ATP-dependent DNA damage sensor activity | Interproscan |
| GO:0035091 | Molecular Function | phosphatidylinositol binding | Interproscan |
| GO:0043130 | Molecular Function | ubiquitin binding | Interproscan |
| GO:0033565 | Cellular Component | ESCRT-0 complex | Interproscan |
| GO:0043328 | Biological Process | protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway | Interproscan |
| GO:0005765 | Cellular Component | lysosomal membrane | Interproscan |
| GO:0015280 | Molecular Function | ligand-gated sodium channel activity | Interproscan |
| GO:0019722 | Biological Process | calcium-mediated signaling | Interproscan |
| GO:0022832 | Molecular Function | voltage-gated channel activity | Interproscan |
| GO:0075509 | Biological Process | endocytosis involved in viral entry into host cell | Interproscan |
| GO:0097682 | Molecular Function | intracellularly phosphatidylinositol-3,5-bisphosphate-gated monatomic cation channel activity | Interproscan |
| GO:0005216 | Molecular Function | monoatomic ion channel activity | Interproscan |
| GO:0006811 | Biological Process | monoatomic ion transport | Interproscan |
| GO:0055085 | Biological Process | transmembrane transport | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K00768 | E2.4.2.21, cobU, cobT; nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase | EC:2.4.2.21 | Peptidoglycan biosynthesis and degradation proteins | ko01011 | deepkoala |
| Ion channels | ko04040 | deepkoala | |||
| Chromosome and associated proteins | ko03036 | deepkoala | |||
| Amino acid related enzymes | ko01007 | deepkoala | |||
| Membrane trafficking | ko04131 | deepkoala | |||
| Mitochondrial biogenesis | ko03029 | deepkoala | |||
| Purine metabolism | ko00230 | deepkoala | |||
| Porphyrin metabolism | ko00860 | deepkoala |