Detailed information of g11109.t1 in Montipora capitata

Genomic Location: Sc0000324:225132...264709
NR annotation: XP_029196674.2, dynein axonemal heavy chain 5-like [Acropora millepora]
Species Montipora capitata · all data for this species · gene families


 Gene Structure
More details in JBrowse  Sequence
CDS
Transcript
Protein
 UniProt (Swiss-Prot top hit)
UniProt accessionDescription
Q8TE73Dynein axonemal heavy chain 5 OS=Homo sapiens OX=9606 GN=DNAH5 PE=1 SV=3
Q91XQ0Dynein axonemal heavy chain 8 OS=Mus musculus OX=10090 GN=Dnah8 PE=1 SV=2
Q8VHE6Dynein axonemal heavy chain 5 OS=Mus musculus OX=10090 GN=Dnah5 PE=1 SV=2
 Gene family
Family typeMembership / link
Orthogroup (gene family)OG0000599 (this species only) · gene tree & orthology

 Pfam domain
Pfam accessionPfam nameDescriptionTypeSource
PF18198
all species →		AAA_lid_11Dynein heavy chain AAA lid domainDomainInterproscan
PF03028
all species →		Dynein_heavyDynein heavy chain region D6 P-loop domain DomainInterproscan
PF12775
all species →		AAA_7P-loop containing dynein motor regionDomainInterproscan
PF18199
all species →		Dynein_CDynein heavy chain C-terminal domainDomainInterproscan
PF17852
all species →		Dynein_AAA_lidDynein heavy chain AAA lid domainDomainInterproscan
PF12780
all species →		AAA_8P-loop containing dynein motor region D4DomainInterproscan
PF12781
all species →		AAA_9ATP-binding dynein motor regionDomainInterproscan
PF17857
all species →		AAA_lid_1AAA+ lid domainDomainInterproscan
PF12777
all species →		MTMicrotubule-binding stalk of dynein motorDomainInterproscan

 InterPro
InterPro termTypeDescriptionSource
IPR041658
all species →		DomainDynein heavy chain AAA lid domainInterproscan
IPR004273
all species →		DomainDynein heavy chain region D6 P-loop domainInterproscan
IPR027417
all species →		Homologous_superfamilyP-loop containing nucleoside triphosphate hydrolaseInterproscan
IPR041228
all species →		DomainDynein heavy chain, C-terminal domainInterproscan
IPR042219
all species →		Homologous_superfamilyDynein heavy chain AAA lid domain superfamilyInterproscan
IPR043160
all species →		Homologous_superfamilyDynein heavy chain, C-terminal domain, barrel regionInterproscan
IPR041466
all species →		DomainDynein heavy chain, AAA 5 extension domainInterproscan
IPR024317
all species →		DomainDynein heavy chain, AAA module D4Interproscan
IPR035706
all species →		DomainDynein heavy chain, ATP-binding dynein motor regionInterproscan
IPR026983
all species →		FamilyDynein heavy chainInterproscan
IPR041589
all species →		DomainDynein heavy chain 3, AAA+ lid domainInterproscan
IPR024743
all species →		DomainDynein heavy chain, coiled coil stalkInterproscan

 PANTHER
PANTHER termDescriptionSource
PTHR46961
all species →		DYNEIN HEAVY CHAIN 1, AXONEMAL-LIKE PROTEINInterproscan

 Gene Ontology
GO termCategoryDescriptionSource
GO:0007018
all species →		Biological Processmicrotubule-based movementInterproscan
GO:0008569
all species →		Molecular Functionminus-end-directed microtubule motor activityInterproscan
GO:0030286
all species →		Cellular Componentdynein complexInterproscan
GO:0045505
all species →		Molecular Functiondynein intermediate chain bindingInterproscan
GO:0051959
all species →		Molecular Functiondynein light intermediate chain bindingInterproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.
 KEGG pathway
KOEnzymeEnzyme IDPathwayMap IDSource
K10408DNAH; dynein axonemal heavy chain-Cytoskeleton proteinsko04812deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of g11109.t1 across 48 RNA-seq samples of Montipora capitata. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

48Samples
48TPM > 0
3Conditions
289.9Max TPM
64.0Mean TPM

By condition

ConditionSamplesTPM > 0 Mean TPMMax TPMMean, relative to max
whole organisms · ambient pH treatment 21 21 62.57 266.21
whole organisms · low pH treatment 15 15 56.34 207.24
whole organisms · extra low pH treatment pH treatment 12 12 76.12 289.88

Per sample · hover a bar for the full sample record

Show the sample table (48 samples)
SRA runConditionTissueDevelopmental stage TreatmentStudyTPM
SRR11452222 whole organisms · ambient pH treatment whole organisms planulae ambient pH treatment SRP254626 266.21
SRR11452230 whole organisms · ambient pH treatment whole organisms planulae ambient pH treatment SRP254626 190.75
SRR11452228 whole organisms · ambient pH treatment whole organisms planulae ambient pH treatment SRP254626 188.74
SRR11452232 whole organisms · ambient pH treatment whole organisms blastula ambient pH treatment SRP254626 125.66
SRR11452231 whole organisms · ambient pH treatment whole organisms blastula ambient pH treatment SRP254626 102.35
SRR11452234 whole organisms · ambient pH treatment whole organisms morula ambient pH treatment SRP254626 86.54
SRR11452233 whole organisms · ambient pH treatment whole organisms morula ambient pH treatment SRP254626 56.62
SRR11452217 whole organisms · ambient pH treatment whole organisms fertilized embryo ambient pH treatment SRP254626 32.47
SRR11452240 whole organisms · ambient pH treatment whole organisms fertilized embryo ambient pH treatment SRP254626 32.03
SRR11452262 whole organisms · ambient pH treatment whole organisms egg ambient pH treatment SRP254626 31.25
SRR11452251 whole organisms · ambient pH treatment whole organisms egg ambient pH treatment SRP254626 28.64
SRR11452263 whole organisms · ambient pH treatment whole organisms egg ambient pH treatment SRP254626 25.58
SRR11452254 whole organisms · ambient pH treatment whole organisms cleavage ambient pH treatment SRP254626 23.39
SRR11452246 whole organisms · ambient pH treatment whole organisms prawn chip ambient pH treatment SRP254626 17.78
SRR11452260 whole organisms · ambient pH treatment whole organisms cleavage ambient pH treatment SRP254626 17.19
SRR11452259 whole organisms · ambient pH treatment whole organisms cleavage ambient pH treatment SRP254626 16.82
SRR11452252 whole organisms · ambient pH treatment whole organisms prawn chip ambient pH treatment SRP254626 16.28
SRR11452250 whole organisms · ambient pH treatment whole organisms prawn chip ambient pH treatment SRP254626 16.25
SRR11452242 whole organisms · ambient pH treatment whole organisms gastrula ambient pH treatment SRP254626 14.54
SRR11452237 whole organisms · ambient pH treatment whole organisms gastrula ambient pH treatment SRP254626 12.92
SRR11452243 whole organisms · ambient pH treatment whole organisms gastrula ambient pH treatment SRP254626 11.96
SRR11452221 whole organisms · low pH treatment whole organisms planulae low pH treatment SRP254626 207.24
SRR11452224 whole organisms · low pH treatment whole organisms planulae low pH treatment SRP254626 203.21
SRR11452223 whole organisms · low pH treatment whole organisms planulae low pH treatment SRP254626 202.54
SRR11452229 whole organisms · low pH treatment whole organisms fertilized embryo low pH treatment SRP254626 38.64
SRR11452218 whole organisms · low pH treatment whole organisms fertilized embryo low pH treatment SRP254626 35.46
SRR11452216 whole organisms · low pH treatment whole organisms fertilized embryo low pH treatment SRP254626 24.09
SRR11452245 whole organisms · low pH treatment whole organisms prawn chip low pH treatment SRP254626 18.15
SRR11452253 whole organisms · low pH treatment whole organisms cleavage low pH treatment SRP254626 17.72
SRR11452255 whole organisms · low pH treatment whole organisms cleavage low pH treatment SRP254626 16.79
SRR11452247 whole organisms · low pH treatment whole organisms prawn chip low pH treatment SRP254626 16.18
SRR11452249 whole organisms · low pH treatment whole organisms prawn chip low pH treatment SRP254626 15.74
SRR11452258 whole organisms · low pH treatment whole organisms cleavage low pH treatment SRP254626 15.05
SRR11452241 whole organisms · low pH treatment whole organisms gastrula low pH treatment SRP254626 13.01
SRR11452236 whole organisms · low pH treatment whole organisms gastrula low pH treatment SRP254626 11.49
SRR11452238 whole organisms · low pH treatment whole organisms gastrula low pH treatment SRP254626 9.72
SRR11452225 whole organisms · extra low pH treatment pH treatment whole organisms planulae extra low pH treatment pH treatment SRP254626 289.88
SRR11452227 whole organisms · extra low pH treatment pH treatment whole organisms planulae extra low pH treatment pH treatment SRP254626 225.63
SRR11452226 whole organisms · extra low pH treatment pH treatment whole organisms planulae extra low pH treatment pH treatment SRP254626 211.06
SRR11452261 whole organisms · extra low pH treatment pH treatment whole organisms fertilized embryo extra low pH treatment pH treatment SRP254626 34.19
SRR11452220 whole organisms · extra low pH treatment pH treatment whole organisms fertilized embryo extra low pH treatment pH treatment SRP254626 27.38
SRR11452219 whole organisms · extra low pH treatment pH treatment whole organisms fertilized embryo extra low pH treatment pH treatment SRP254626 26.79
SRR11452256 whole organisms · extra low pH treatment pH treatment whole organisms cleavage extra low pH treatment pH treatment SRP254626 26.50
SRR11452257 whole organisms · extra low pH treatment pH treatment whole organisms cleavage extra low pH treatment pH treatment SRP254626 16.06
SRR11452248 whole organisms · extra low pH treatment pH treatment whole organisms prawn chip extra low pH treatment pH treatment SRP254626 16.03
SRR11452244 whole organisms · extra low pH treatment pH treatment whole organisms prawn chip extra low pH treatment pH treatment SRP254626 15.90
SRR11452239 whole organisms · extra low pH treatment pH treatment whole organisms gastrula extra low pH treatment pH treatment SRP254626 12.48
SRR11452235 whole organisms · extra low pH treatment pH treatment whole organisms gastrula extra low pH treatment pH treatment SRP254626 11.52

Source: CnidoSite RNA-seq expression matrices (MCAPI_TPM, StringTie quantification over 48 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.

Co-expression network

Genes whose expression across the transcriptome samples of Montipora capitata tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

DirectionPartnersMost correlated partnerPCC
Positively correlated29g4047.t10.994163711293285
Negatively correlated4g15027.t1-0.923805179185387

Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Montipora capitata, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

AnalysisWhat it doesStatus
Primer designDesign PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.template foundopen →
BLASTSearch this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.template foundopen →
Expression heatmapDraw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.readyopen →
Gene family / orthogroupLook this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.open →
Gene set analysisStart a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.open →
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