Detailed information of g1141.t1 in Calvadosia cruxmelitensis

Genomic Location: :...
NR annotation: XP_004990052.1, thymidylate synthase [Salpingoeca rosetta]


 Gene Structure
More details in Jbrowse  Sequence
CDS
Transcript
Protein
 Uniprot Gene family
Uniprot termDescription
P04818Thymidylate synthase OS=Homo sapiens OX=9606 GN=TYMS PE=1 SV=3
O81395Bifunctional dihydrofolate reductase-thymidylate synthase OS=Zea mays OX=4577 GN=DRTS PE=2 SV=1
P07607Thymidylate synthase OS=Mus musculus OX=10090 GN=Tyms PE=1 SV=1
Gene familySubfamily
Ubiquitin FamilyE3|E3 activity|HECT

 Pfam domain
Pfam accessionPfam nameDescriptionTypeSource
PF00005ABC_tranABC transporterDomainInterproscan
PF08352oligo_HPYOligopeptide/dipeptide transporter, C-terminal regionFamilyInterproscan
PF00303Thymidylat_syntThymidylate synthaseDomainInterproscan
PF08718GLTPGlycolipid transfer protein (GLTP)DomainInterproscan
PF02825WWEWWE domainFamilyInterproscan
PF18701DUF5641Family of unknown function (DUF5641)DomainInterproscan

 InterPro
InterPro termTypeDescriptionSource
IPR000569DomainHECT domainInterproscan
IPR035983Homologous_superfamilyHECT, E3 ligase catalytic domainInterproscan
IPR003593DomainAAA+ ATPase domainInterproscan
IPR050388FamilyABC Transporter, Nickel and Peptide ImportInterproscan
IPR027417Homologous_superfamilyP-loop containing nucleoside triphosphate hydrolaseInterproscan
IPR013563DomainOligopeptide/dipeptide ABC transporter, C-terminalInterproscan
IPR003439DomainABC transporter-like, ATP-binding domainInterproscan
IPR017871Conserved_siteABC transporter-like, conserved siteInterproscan
IPR036926Homologous_superfamilyThymidylate synthase/dCMP hydroxymethylase superfamilyInterproscan
IPR000398FamilyThymidylate synthaseInterproscan
IPR045097FamilyThymidylate synthase/dCMP hydroxymethylaseInterproscan
IPR020940Active_siteThymidylate synthase, active siteInterproscan
IPR023451DomainThymidylate synthase/dCMP hydroxymethylase domainInterproscan
IPR036497Homologous_superfamilyGlycolipid transfer protein superfamilyInterproscan
IPR014830DomainGlycolipid transfer protein domainInterproscan
IPR037197Homologous_superfamilyWWE domain superfamilyInterproscan
IPR004170DomainWWE domainInterproscan
IPR036770Homologous_superfamilyAnkyrin repeat-containing domain superfamilyInterproscan
IPR000626DomainUbiquitin-like domainInterproscan
IPR040676DomainDomain of unknown function DUF5641Interproscan

 PANTHER
PANTHER termDescriptionSource
PTHR43297OLIGOPEPTIDE TRANSPORT ATP-BINDING PROTEIN APPDInterproscan
PTHR11548THYMIDYLATE SYNTHASE 1Interproscan
PTHR10219GLYCOLIPID TRANSFER PROTEIN-RELATEDInterproscan
PTHR23509PA-PL1 PHOSPHOLIPASE FAMILYInterproscan
PTHR33395TRANSCRIPTASE, PUTATIVE-RELATED-RELATEDInterproscan
PTHR22955RETROTRANSPOSONInterproscan

 Gene Ontology
GO termsCategoryDescriptionSource
GO:0004842Molecular Functionubiquitin-protein transferase activityInterproscan
GO:0016887Molecular FunctionATP hydrolysis activityInterproscan
GO:0000166Molecular Functionnucleotide bindingInterproscan
GO:0005524Molecular FunctionATP bindingInterproscan
GO:0015833Biological Processpeptide transportInterproscan
GO:0004799Molecular Functionthymidylate synthase activityInterproscan
GO:0006231Biological ProcessdTMP biosynthetic processInterproscan
GO:0005739Cellular ComponentmitochondrionInterproscan
GO:0005829Cellular ComponentcytosolInterproscan
GO:0016741Molecular Functiontransferase activity, transferring one-carbon groupsInterproscan
GO:0005737Cellular ComponentcytoplasmInterproscan
GO:0120009Biological Processintermembrane lipid transferInterproscan
GO:0120013Molecular Functionlipid transfer activityInterproscan
GO:0004620Molecular Functionphospholipase activityInterproscan
GO:0005515Molecular Functionprotein bindingInterproscan
GO:0007508Biological Processlarval heart developmentInterproscan
GO:0031012Cellular Componentextracellular matrixInterproscan
GO:0061343Biological Processcell adhesion involved in heart morphogenesisInterproscan

 KEGG pathway
KOEnzymeEnzyme IDpathwaymapIDSource
K00560thyA, TYMS; thymidylate synthaseEC:2.1.1.45
Antifolate resistanceko01523deepkoala

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