Genomic Location: :...
NR annotation: KAJ8022346.1, Leucine-, glutamate- and lysine-rich protein 1 [Holothuria leucospilota]
| CDS | |||||
| Transcript |
| Protein |
| Uniprot term | Description | ||||
|---|---|---|---|---|---|
| Q6DFC6 | WD repeat-containing protein 75 OS=Xenopus laevis OX=8355 GN=wdr75 PE=2 SV=1 | ||||
| Q7ZVR1 | WD repeat-containing protein 75 OS=Danio rerio OX=7955 GN=wdr75 PE=2 SV=2 | ||||
| Q3U821 | WD repeat-containing protein 75 OS=Mus musculus OX=10090 GN=Wdr75 PE=1 SV=1 |
| Gene family | Subfamily |
|---|---|
| Ubiquitin Family | UBD|Other|Beta-prp |
| Ubiquitin Family | E3|E3 adaptor Cullin RING|CDC20 |
| Ubiquitin Family | E3|E3 adaptor Cullin RING|DWD |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF00999 | Na_H_Exchanger | Sodium/hydrogen exchanger family | Family | Interproscan |
| PF02775 | TPP_enzyme_C | Thiamine pyrophosphate enzyme, C-terminal TPP binding domain | Domain | Interproscan |
| PF00205 | TPP_enzyme_M | Thiamine pyrophosphate enzyme, central domain | Domain | Interproscan |
| PF10226 | CCDC85 | CCDC85 family | Family | Interproscan |
| PF03131 | bZIP_Maf | bZIP Maf transcription factor | Coiled-coil | Interproscan |
| PF00189 | Ribosomal_S3_C | Ribosomal protein S3, C-terminal domain | Domain | Interproscan |
| PF07650 | KH_2 | KH domain | Domain | Interproscan |
| PF00024 | PAN_1 | PAN domain | Domain | Interproscan |
| PF10296 | MMM1 | Maintenance of mitochondrial morphology protein 1 | Family | Interproscan |
| PF17820 | PDZ_6 | PDZ domain | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR006153 | Domain | Cation/H+ exchanger | Interproscan |
| IPR018422 | Family | Cation/H+ exchanger, CPA1 family | Interproscan |
| IPR029035 | Homologous_superfamily | DHS-like NAD/FAD-binding domain superfamily | Interproscan |
| IPR045229 | Family | Thiamine pyrophosphate enzyme | Interproscan |
| IPR029061 | Homologous_superfamily | Thiamin diphosphate-binding fold | Interproscan |
| IPR011766 | Domain | Thiamine pyrophosphate enzyme, TPP-binding | Interproscan |
| IPR012000 | Domain | Thiamine pyrophosphate enzyme, central domain | Interproscan |
| IPR015943 | Homologous_superfamily | WD40/YVTN repeat-like-containing domain superfamily | Interproscan |
| IPR036322 | Homologous_superfamily | WD40-repeat-containing domain superfamily | Interproscan |
| IPR001680 | Repeat | WD40 repeat | Interproscan |
| IPR019359 | Family | CCDC85 family | Interproscan |
| IPR046347 | Homologous_superfamily | Basic-leucine zipper domain superfamily | Interproscan |
| IPR004827 | Domain | Basic-leucine zipper domain | Interproscan |
| IPR024874 | Family | Transcription factor Maf family | Interproscan |
| IPR008917 | Homologous_superfamily | Transcription factor, Skn-1-like, DNA-binding domain superfamily | Interproscan |
| IPR004826 | Domain | Basic leucine zipper domain, Maf-type | Interproscan |
| IPR015946 | Homologous_superfamily | K homology domain-like, alpha/beta | Interproscan |
| IPR001351 | Domain | Small ribosomal subunit protein uS3, C-terminal | Interproscan |
| IPR009019 | Homologous_superfamily | K homology domain superfamily, prokaryotic type | Interproscan |
| IPR036419 | Homologous_superfamily | Ribosomal protein S3, C-terminal domain superfamily | Interproscan |
| IPR005703 | Family | Small ribosomal subunit protein uS3, eukaryotic/archaeal | Interproscan |
| IPR004044 | Domain | K Homology domain, type 2 | Interproscan |
| IPR003609 | Domain | PAN/Apple domain | Interproscan |
| IPR001478 | Domain | PDZ domain | Interproscan |
| IPR019411 | Domain | MMM1 domain | Interproscan |
| IPR031468 | Domain | Synaptotagmin-like mitochondrial-lipid-binding domain | Interproscan |
| IPR039275 | Family | PDZ domain-containing protein 8 | Interproscan |
| IPR036034 | Homologous_superfamily | PDZ superfamily | Interproscan |
| IPR041489 | Domain | PDZ domain 6 | Interproscan |
| IPR038799 | Family | Protein LEKR1 | Interproscan |
| IPR050951 | Family | Retrovirus-related Pol polyprotein | Interproscan |
| IPR001584 | Domain | Integrase, catalytic core | Interproscan |
| IPR012337 | Homologous_superfamily | Ribonuclease H-like superfamily | Interproscan |
| IPR036397 | Homologous_superfamily | Ribonuclease H superfamily | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR10110 | SODIUM/HYDROGEN EXCHANGER | Interproscan |
| PTHR18968 | THIAMINE PYROPHOSPHATE ENZYMES | Interproscan |
| PTHR44215 | WD REPEAT-CONTAINING PROTEIN 75 | Interproscan |
| PTHR13546 | RE60986P | Interproscan |
| PTHR10129 | TRANSCRIPTION FACTOR MAF | Interproscan |
| PTHR11760 | 30S/40S RIBOSOMAL PROTEIN S3 | Interproscan |
| PTHR21519 | PDZ DOMAIN-CONTAINING PROTEIN 8 | Interproscan |
| PTHR34251 | LEUCINE-, GLUTAMATE- AND LYSINE-RICH PROTEIN 1 | Interproscan |
| PTHR37984 | PROTEIN CBG26694 | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0006812 | Biological Process | monoatomic cation transport | Interproscan |
| GO:0015297 | Molecular Function | antiporter activity | Interproscan |
| GO:0016020 | Cellular Component | membrane | Interproscan |
| GO:0055085 | Biological Process | transmembrane transport | Interproscan |
| GO:1902600 | Biological Process | proton transmembrane transport | Interproscan |
| GO:0005886 | Cellular Component | plasma membrane | Interproscan |
| GO:0015385 | Molecular Function | sodium:proton antiporter activity | Interproscan |
| GO:0015386 | Molecular Function | potassium:proton antiporter activity | Interproscan |
| GO:0051453 | Biological Process | regulation of intracellular pH | Interproscan |
| GO:0071805 | Biological Process | potassium ion transmembrane transport | Interproscan |
| GO:0098719 | Biological Process | sodium ion import across plasma membrane | Interproscan |
| GO:0003984 | Molecular Function | acetolactate synthase activity | Interproscan |
| GO:0005948 | Cellular Component | acetolactate synthase complex | Interproscan |
| GO:0009097 | Biological Process | isoleucine biosynthetic process | Interproscan |
| GO:0009099 | Biological Process | L-valine biosynthetic process | Interproscan |
| GO:0050660 | Molecular Function | flavin adenine dinucleotide binding | Interproscan |
| GO:0003824 | Molecular Function | catalytic activity | Interproscan |
| GO:0030976 | Molecular Function | thiamine pyrophosphate binding | Interproscan |
| GO:0000287 | Molecular Function | magnesium ion binding | Interproscan |
| GO:0005515 | Molecular Function | protein binding | Interproscan |
| GO:0003723 | Molecular Function | RNA binding | Interproscan |
| GO:0005730 | Cellular Component | nucleolus | Interproscan |
| GO:0045943 | Biological Process | positive regulation of transcription by RNA polymerase I | Interproscan |
| GO:2000234 | Biological Process | positive regulation of rRNA processing | Interproscan |
| GO:0005634 | Cellular Component | nucleus | Interproscan |
| GO:0045892 | Biological Process | negative regulation of DNA-templated transcription | Interproscan |
| GO:0003700 | Molecular Function | DNA-binding transcription factor activity | Interproscan |
| GO:0006355 | Biological Process | regulation of DNA-templated transcription | Interproscan |
| GO:0000978 | Molecular Function | RNA polymerase II cis-regulatory region sequence-specific DNA binding | Interproscan |
| GO:0000981 | Molecular Function | DNA-binding transcription factor activity, RNA polymerase II-specific | Interproscan |
| GO:0006357 | Biological Process | regulation of transcription by RNA polymerase II | Interproscan |
| GO:0003677 | Molecular Function | DNA binding | Interproscan |
| GO:0003735 | Molecular Function | structural constituent of ribosome | Interproscan |
| GO:0006412 | Biological Process | translation | Interproscan |
| GO:0022627 | Cellular Component | cytosolic small ribosomal subunit | Interproscan |
| GO:2001235 | Biological Process | positive regulation of apoptotic signaling pathway | Interproscan |
| GO:0015935 | Cellular Component | small ribosomal subunit | Interproscan |
| GO:0008289 | Molecular Function | lipid binding | Interproscan |
| GO:0044233 | Cellular Component | mitochondria-associated endoplasmic reticulum membrane contact site | Interproscan |
| GO:0051560 | Biological Process | mitochondrial calcium ion homeostasis | Interproscan |
| GO:1990456 | Biological Process | mitochondrion-endoplasmic reticulum membrane tethering | Interproscan |
| GO:0015074 | Biological Process | DNA integration | Interproscan |
| GO:0003676 | Molecular Function | nucleic acid binding | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K09037 | MAFF_G_K; transcription factor MAFF/G/K | - | Ribosome biogenesis | ko03009 | deepkoala |
| Transcription factors | ko03000 | deepkoala |