Gene detail

Detailed information of g11864.t1 in Montipora capitata

Genomic Location: Sc0000365:268380...286618
NR annotation: XP_029193213.2, rasGAP-activating-like protein 1 isoform X2 [Acropora millepora]
Species Montipora capitata · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

g11864.t1

atggcggagagtatcattttgtaccttcgaataggcgagggaaagaacctcccgcgaaaagatctgtcaggaaagagcgatccatattgtattgtcaaagtggacaaccacactgtggcgagaactgcgacaatttggagagatctggagccgttttggggcgaggaatacactctctttgttccacctacttttaaaaacttttcagtacacgtcttcgacgaggatacgtttggagttgatgacgtcattggaagagtgacttttgaccgggaaatgttgatgcaagaccccaaagaaaaggagaaatggtttccactgattcctgcttatcagatgcacaattattcagatattcaaggggagattaagatacaaacaacgctttacgagcagggagatgtaaagaaaataaaagcaagaatcctggaaatcaggaaccttcctgatgatgcttgtagcaacgtggagccttcagttacactgtcggtgctcggagagaatggttcatgtcaaacggtgctaacgttgagagagatacttctcaaactccccgagggaaacaagaaattttgggttcccaataaacagaagtatttggaatttcacttgaaggaaccaacatgtgaatacaagatgacagcccttgtgaagattgaatcagaaactcactggttttccggtcaggcttcattcatcttaccagagatcaagaacggtcaaattaaggaaatatggtacaaactacagccattgccaccaaccacaaaacaaaaaccggaaagtctcggcagtattaggatgaaagttcgtctaacacaggagcgcatcctgccacaacagtactaccagtctctcgtggagattctaatgaattctgtctcggacccagagagccagagtcccactgcgctgagcttaatagagaagttgacgcccgctgaccagatgacattagcttgccaactggttcgactgtttatcggtcagggattggtaatacagtttctggactacatgacacttcaggagataaggaagtcgaataatccaccaactctgtttagaggtaacagtctcgcagcaaaatgcatggagcaatttatgaagattgtgggtatgccatatctgtctgacacactaaagccagttcttgacagaatttttgaagagcataaatactgtgagttggacccaagtaaagtggctgtaaggcgcaaatcaagtaccttaaggcgtcttagtctaaggtcagttgacgacgaacaagacagaagcttatcagtgcttaccacttatctggaagccatcatgacgtccattttaagctcagttaaggcatgcccacgctacatgcgaatagcattcaggaacatcgcgcgcagagtgtcagaccactttggagataaacctgaatttgaggacgcgaagtacacagccgtgagtggttttctgttccttcgtttctacgctccagcaattcttggacccaagctctttggtttacaggacaaccacacggacaagaacgtctcacgcactctaacaattttggccaagactgtgcaaaagatcggaaacctagagtttcctcgtcgcggcgggaaggaggaatggatggaatcgctgcacacatggatcgcattctacacagatgaagtcaaggattttttagacaaacttgttgaagtggatgacgaagaagttaccggatgtgatgacaagcgaaccgtattcagccactcagtcgtcatcaaagaaggtttcatcaaaaagtgcctccgcagggacaccagactgtcaccctcattcaacttcaaaaagcgctactgttggctgaccaccgaaagtttcctgtacgctgaatcgaatgactctcagacgagacagtttcttccaacaaagaaaatccttgccattgagcgagttgatgaggcggcatttcaaaatccaaatgtttttcaagtggtaagcaaagatggcggggatgcgtttcaaatcctataccttgcggcacaggatgtgaatgaaatgaatcagtggttgtcagcgataaggaagataaccatttccaatgcgatatcgttaaatgaatttcaccccggagtctttcgcaaaaccaaatggacttgttgcaagcgtcttcttcggcaagctgaagggtgccgaccaacacacgcccacgtgactttgagtgactggcgagatccactcgactcagatttcgaagcacaaatgattttcactcagctgtttcaaagtcgcgaggaactgagacaaagattccagcaaactgctcaatgcgaaaaagatccaaaagaccacagtaacaattacctggacacgaaaccgcgcagaaagataactacgacgccagacttgacagtcgagtttgacaacgaaagaactgtggcggaaagattactagaggtgataaatgaactagaagaagctcatcaaacatttgaggagaaagtgacatag

Transcript

g11864.t1

ATGGCGGAGAGTATCATTTTGTACCTTCGAATAGGCGAGGGAAAGAACCTCCCGCGAAAAGATCTGTCAGGAAAGAGCGATCCATATTGTATTGTCAAAGTGGACAACCACACTGTGGCGAGAACTGCGACAATTTGGAGAGATCTGGAGCCGTTTTGGGGCGAGGAATACACTCTCTTTGTTCCACCTACTTTTAAAAACTTTTCAGTACACGTCTTCGACGAGGATACGTTTGGagttgatgacgtcattggaAGAGTGACTTTTGACCGGGAAATGTTGATGCAAGACCCCAAAGAAAAGGAGAAATGGTTTCCACTGATTCCTGCTTATCAGATGCACAATTATTCAGATATTCAAGGGGAGATTAAGATACAAACAACGCTTTACGAGCAGGGAGatgtaaagaaaataaaagcaagaaTCCTGGAAATCAGGAACCTTCCTGATGATGCTTGTAGCAACGTGGAGCCTTCAGTTACACTGTCGGTGCTCGGAGAGAATGGTTCATGTCAAACGGTGCTAACGTTGAGAGAGATACTTCTCAAACTCCCCGAGGGAAACAAGAAATTTTGGGTTCCCAATAAACAGAAGTATTTGGAATTTCACTTGAAGGAACCAACATGTGAATACAAGATGACAGCCCTTGTGAAGATTGAATCAGAAACTCACTGGTTTTCCGGTCAGGCTTCATTCATCTTACCAGAGATCAAGAACGGTCAAATTAAGGAAATATGGTACAAACTACAGCCATTGCCACcaaccacaaaacaaaaaccGGAAAGTCTCGGCAGTATTAGGATGAAAGTTCGTCTAACACAGGAGCGCATCCTGCCACAACAGTACTACCAGTCTCTCGTGGAGATTCTAATGAATTCTGTCTCGGACCCAGAGAGCCAGAGTCCCACTGCGCTGAGCTTAATAGAGAAGTTGACGCCCGCTGACCAGATGACATTAGCTTGCCAACTGGTTCGACTGTTTATCGGTCAGGGATTGGTAATACAGTTTCTGGACTACATGACACTTCAGGAGATAAGGAAGTCGAATAATCCACCAACTCTGTTTAGAGGTAACAGTCTCGCAGCAAAATGCATGGAGCAATTTATGAAGattgTGGGTATGCCATATCTGTCTGACACACTAAAGCCAGTTCTTGACAGAATTTTTGAAGAGCATAAATACTGTGAGTTGGACCCAAGTAAAGTGGCTGTAAGGCGCAAATCAAGTACCTTAAGgCGTCTTAGTCTAAGGTCAGTTGACGACGAACAAGACAGAAGCTTATCAGTGCTTACCACTTATCTGGAAGCCATCATGACGTCCATTTTAAGCTCAGTTAAGGCATGCCCACGCTACATGCGAATAGCATTCAGGAACATCGCGCGCAGAGTGTCAGACCACTTTGGAGATAAACCTGAATTTGAGGACGCGAAGTACACAGCCGTGAGTGGTTTTCTGTTCCTTCGTTTCTACGCTCCAGCAATTCTTGGACCCAAGCTCTTTGGTTTACAGGACAACCACACGGACAAGAACGTCTCACGCACTCTAACAATTTTGGCCAAGACTGTGCAAAAGATCGGAAACCTAGAGTTTCCTCGTCGCGGCGGGAAGGAGGAATGGATGGAATCGCTGCACACATGGATCGCATTCTACACAGATGAAGTCAAGGATTTTTTAGACAAACTTGTTGAAGTGGATGACGAAGAAGTTACCGGATGTGATGACAAGCGAACCGTATTCAGCCACTCAGTCGTCATCAAAGAAGGTTTCATCAAAAAGTGCCTCCGCAGGGACACCAGACTGTCACCCTCATTCAACTTCAAAAAGCGCTACTGTTGGCTGACCACCGAAAGTTTCCTGTACGCTGAATCGAATGACTCTCAGACGAGACAGTTTCTTCCAACAAAGAAAATCCTTGCCATTGAGCGAGTTGATGAGGCGGCATTTCAAAATCCAAATGTTTTTCAAGTGGTAAGCAAAGATGGCGGGGATGCGTTTCAAATCCTATACCTTGCGGCACAGGatgtgaatgaaatgaatcagTGGTTGTCAGCGATAAGGAAGATAACCATTTCCAATGCGATATCGTTAAATGAATTTCACCCCGGAGTCTTTCGCAAAACCAAATGGACTTGTTGCAAGCGTCTTCTTCGGCAAGCTGAAGGGTGCCGACCAACACACGCCCACGTGACTTTGAGTGACTGGCGAGATCCACTCGACTCAGATTTCGAAGCACAAATGATTTTCACTCAGCTGTTTCAAAGTCGCGAGGAACTGAGACAAAGATTCCAGCAAACTGCTCAATGCGAAAAAGATCCAAAAGACCACAGTAACAATTACCTGGACACGAAACCGCGCAGAAAGATAACTACGACGCCAGACTTGACAGTCGAGTTTGACAACGAAAGAACTGTGGCGGAAAGATTACTAGAGGTGATAAATGAACTAGAAGAAGCTCATCAAACatttgaggagaaagtgacatAG

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
O95294	RasGAP-activating-like protein 1 OS=Homo sapiens OX=9606 GN=RASAL1 PE=1 SV=3
Q9Z268	RasGAP-activating-like protein 1 OS=Mus musculus OX=10090 GN=Rasal1 PE=1 SV=2
Q6PFQ7	Ras GTPase-activating protein 4 OS=Mus musculus OX=10090 GN=Rasa4 PE=1 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0006928 (this species only) · gene tree & orthology

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF00168 all species →	C2	C2 domain	Domain	Interproscan
PF00779 all species →	BTK	BTK motif	Motif	Interproscan
PF00616 all species →	RasGAP	GTPase-activator protein for Ras-like GTPase	Family	Interproscan
PF00169 all species →	PH	PH domain	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR001849 all species →	Domain	Pleckstrin homology domain	Interproscan
IPR039360 all species →	Family	Ras GTPase-activating protein	Interproscan
IPR001936 all species →	Domain	Ras GTPase-activating domain	Interproscan
IPR011993 all species →	Homologous_superfamily	PH-like domain superfamily	Interproscan
IPR000008 all species →	Domain	C2 domain	Interproscan
IPR001562 all species →	Conserved_site	Zinc finger, Btk motif	Interproscan
IPR035892 all species →	Homologous_superfamily	C2 domain superfamily	Interproscan
IPR008936 all species →	Homologous_superfamily	Rho GTPase activation protein	Interproscan
IPR023152 all species →	Conserved_site	Ras GTPase-activating protein, conserved site	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR10194 all species →	RAS GTPASE-ACTIVATING PROTEINS	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0043087 all species →	Biological Process	regulation of GTPase activity	Interproscan
GO:0035556 all species →	Biological Process	intracellular signal transduction	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K17632	RASAL1; RAS protein activator-like 1	-	Ras signaling pathway	ko04014	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of g11864.t1 across 48 RNA-seq samples of Montipora capitata. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

48Samples

25TPM > 0

3Conditions

6.6Max TPM

1.1Mean TPM

By condition

Condition	Samples	TPM > 0	Mean TPM	Max TPM
whole organisms · ambient pH treatment	21	12	1.20	6.61
whole organisms · low pH treatment	15	6	0.95	4.90
whole organisms · extra low pH treatment pH treatment	12	7	0.96	4.54

Per sample · hover a bar for the full sample record · show / hide the sample table

SRA run	Condition	Tissue	Developmental stage	Treatment	Study	TPM
SRR11452242	whole organisms · ambient pH treatment	whole organisms	gastrula	ambient pH treatment	SRP254626	6.61
SRR11452243	whole organisms · ambient pH treatment	whole organisms	gastrula	ambient pH treatment	SRP254626	5.16
SRR11452237	whole organisms · ambient pH treatment	whole organisms	gastrula	ambient pH treatment	SRP254626	4.05
SRR11452233	whole organisms · ambient pH treatment	whole organisms	morula	ambient pH treatment	SRP254626	2.97
SRR11452234	whole organisms · ambient pH treatment	whole organisms	morula	ambient pH treatment	SRP254626	1.79
SRR11452232	whole organisms · ambient pH treatment	whole organisms	blastula	ambient pH treatment	SRP254626	1.58
SRR11452250	whole organisms · ambient pH treatment	whole organisms	prawn chip	ambient pH treatment	SRP254626	0.78
SRR11452231	whole organisms · ambient pH treatment	whole organisms	blastula	ambient pH treatment	SRP254626	0.67
SRR11452228	whole organisms · ambient pH treatment	whole organisms	planulae	ambient pH treatment	SRP254626	0.57
SRR11452230	whole organisms · ambient pH treatment	whole organisms	planulae	ambient pH treatment	SRP254626	0.45
SRR11452246	whole organisms · ambient pH treatment	whole organisms	prawn chip	ambient pH treatment	SRP254626	0.33
SRR11452252	whole organisms · ambient pH treatment	whole organisms	prawn chip	ambient pH treatment	SRP254626	0.29
SRR11452217	whole organisms · ambient pH treatment	whole organisms	fertilized embryo	ambient pH treatment	SRP254626	0.00
SRR11452222	whole organisms · ambient pH treatment	whole organisms	planulae	ambient pH treatment	SRP254626	0.00
SRR11452240	whole organisms · ambient pH treatment	whole organisms	fertilized embryo	ambient pH treatment	SRP254626	0.00
SRR11452251	whole organisms · ambient pH treatment	whole organisms	egg	ambient pH treatment	SRP254626	0.00
SRR11452254	whole organisms · ambient pH treatment	whole organisms	cleavage	ambient pH treatment	SRP254626	0.00
SRR11452259	whole organisms · ambient pH treatment	whole organisms	cleavage	ambient pH treatment	SRP254626	0.00
SRR11452260	whole organisms · ambient pH treatment	whole organisms	cleavage	ambient pH treatment	SRP254626	0.00
SRR11452262	whole organisms · ambient pH treatment	whole organisms	egg	ambient pH treatment	SRP254626	0.00
SRR11452263	whole organisms · ambient pH treatment	whole organisms	egg	ambient pH treatment	SRP254626	0.00
SRR11452241	whole organisms · low pH treatment	whole organisms	gastrula	low pH treatment	SRP254626	4.90
SRR11452236	whole organisms · low pH treatment	whole organisms	gastrula	low pH treatment	SRP254626	3.81
SRR11452238	whole organisms · low pH treatment	whole organisms	gastrula	low pH treatment	SRP254626	3.19
SRR11452223	whole organisms · low pH treatment	whole organisms	planulae	low pH treatment	SRP254626	1.07
SRR11452221	whole organisms · low pH treatment	whole organisms	planulae	low pH treatment	SRP254626	0.75
SRR11452224	whole organisms · low pH treatment	whole organisms	planulae	low pH treatment	SRP254626	0.47
SRR11452216	whole organisms · low pH treatment	whole organisms	fertilized embryo	low pH treatment	SRP254626	0.00
SRR11452218	whole organisms · low pH treatment	whole organisms	fertilized embryo	low pH treatment	SRP254626	0.00
SRR11452229	whole organisms · low pH treatment	whole organisms	fertilized embryo	low pH treatment	SRP254626	0.00
SRR11452245	whole organisms · low pH treatment	whole organisms	prawn chip	low pH treatment	SRP254626	0.00
SRR11452247	whole organisms · low pH treatment	whole organisms	prawn chip	low pH treatment	SRP254626	0.00
SRR11452249	whole organisms · low pH treatment	whole organisms	prawn chip	low pH treatment	SRP254626	0.00
SRR11452253	whole organisms · low pH treatment	whole organisms	cleavage	low pH treatment	SRP254626	0.00
SRR11452255	whole organisms · low pH treatment	whole organisms	cleavage	low pH treatment	SRP254626	0.00
SRR11452258	whole organisms · low pH treatment	whole organisms	cleavage	low pH treatment	SRP254626	0.00
SRR11452239	whole organisms · extra low pH treatment pH treatment	whole organisms	gastrula	extra low pH treatment pH treatment	SRP254626	4.54
SRR11452235	whole organisms · extra low pH treatment pH treatment	whole organisms	gastrula	extra low pH treatment pH treatment	SRP254626	4.45
SRR11452225	whole organisms · extra low pH treatment pH treatment	whole organisms	planulae	extra low pH treatment pH treatment	SRP254626	0.79
SRR11452244	whole organisms · extra low pH treatment pH treatment	whole organisms	prawn chip	extra low pH treatment pH treatment	SRP254626	0.68
SRR11452227	whole organisms · extra low pH treatment pH treatment	whole organisms	planulae	extra low pH treatment pH treatment	SRP254626	0.49
SRR11452226	whole organisms · extra low pH treatment pH treatment	whole organisms	planulae	extra low pH treatment pH treatment	SRP254626	0.42
SRR11452256	whole organisms · extra low pH treatment pH treatment	whole organisms	cleavage	extra low pH treatment pH treatment	SRP254626	0.21
SRR11452219	whole organisms · extra low pH treatment pH treatment	whole organisms	fertilized embryo	extra low pH treatment pH treatment	SRP254626	0.00
SRR11452220	whole organisms · extra low pH treatment pH treatment	whole organisms	fertilized embryo	extra low pH treatment pH treatment	SRP254626	0.00
SRR11452248	whole organisms · extra low pH treatment pH treatment	whole organisms	prawn chip	extra low pH treatment pH treatment	SRP254626	0.00
SRR11452257	whole organisms · extra low pH treatment pH treatment	whole organisms	cleavage	extra low pH treatment pH treatment	SRP254626	0.00
SRR11452261	whole organisms · extra low pH treatment pH treatment	whole organisms	fertilized embryo	extra low pH treatment pH treatment	SRP254626	0.00

Source: CnidoSite RNA-seq expression matrices (MCAPI_TPM, StringTie quantification over 48 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.