Genomic Location: :...
NR annotation: XP_047134035.1, E3 ubiquitin-protein ligase HACE1 [Hydra vulgaris]
| CDS | |||||
| g1212.t1 | |||||
| Transcript |
| g1212.t1 |
| Protein |
| g1212.t1.1 |
| Uniprot term | Description | ||||
|---|---|---|---|---|---|
| Q28BK1 | E3 ubiquitin-protein ligase HACE1 OS=Xenopus tropicalis OX=8364 GN=hace1 PE=2 SV=1 | ||||
| Q6DCL5 | E3 ubiquitin-protein ligase HACE1 OS=Xenopus laevis OX=8355 GN=hace1 PE=2 SV=1 | ||||
| Q8IYU2 | E3 ubiquitin-protein ligase HACE1 OS=Homo sapiens OX=9606 GN=HACE1 PE=1 SV=2 |
| Gene family | Subfamily |
|---|---|
| Ubiquitin Family | E3|E3 activity|HECT |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF00632 | HECT | HECT-domain (ubiquitin-transferase) | Domain | Interproscan |
| PF12796 | Ank_2 | Ankyrin repeats (3 copies) | Repeat | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR002110 | Repeat | Ankyrin repeat | Interproscan |
| IPR000569 | Domain | HECT domain | Interproscan |
| IPR050409 | Family | E3 ubiquitin-protein ligase | Interproscan |
| IPR036770 | Homologous_superfamily | Ankyrin repeat-containing domain superfamily | Interproscan |
| IPR035983 | Homologous_superfamily | HECT, E3 ligase catalytic domain | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR11254 | HECT DOMAIN UBIQUITIN-PROTEIN LIGASE | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0005515 | Molecular Function | protein binding | Interproscan |
| GO:0004842 | Molecular Function | ubiquitin-protein transferase activity | Interproscan |
| GO:0000139 | Cellular Component | Golgi membrane | Interproscan |
| GO:0000209 | Biological Process | protein polyubiquitination | Interproscan |
| GO:0005634 | Cellular Component | nucleus | Interproscan |
| GO:0005737 | Cellular Component | cytoplasm | Interproscan |
| GO:0007030 | Biological Process | Golgi organization | Interproscan |
| GO:0016567 | Biological Process | protein ubiquitination | Interproscan |
| GO:0061025 | Biological Process | membrane fusion | Interproscan |
| GO:0061630 | Molecular Function | ubiquitin protein ligase activity | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K12166 | HACE1; E3 ubiquitin-protein ligase HACE1 | EC:2.3.2.26 | Ubiquitin system | ko04121 | deepkoala |