Gene detail

Detailed information of g12280.t1 in Montipora capitata

Genomic Location: Sc0000388:218040...224260
NR annotation: XP_029190468.2, lysosomal alpha-mannosidase-like isoform X1 [Acropora millepora]
Species Montipora capitata · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

g12280.t1

atggctgatccttccaagcggtttatttacgtggaaatcgcgttttttgagcgatggtggaacgaacaaagtgaagccatgcgagcagatgtaaagaagcttgtttccgaaaagagacttgagtttatcaacgcaggatggtgtatgaacgatgaagcagccacacattacaatggtattattgatcaaatgacttatggcttaaactttgtccaagaaacatttggttccgatgcaaggccaaggatagcctggcatattgatcccttcggtcactcgaatgaacaagcctccatcttctctcaaatgtcattcgatggattcttctttggtcgcatcgattaccaagacaaagatcttcgtctggagcagcagagaatggaactggtgtggagaggaagcagaagtttagcgcaaaagtcggacattttcacaggcgtgctttacaatgggtataatccgcctaaaggattttgctatgatcagttttgtgcagatccgcctgtacaagatgacccaaacctgtttgacctcaatgtcaaagaaagagttgcaaaatttgtagccacaacttgcagccaggctttgcactacaaaaccaaccacataatgttgacgatgggatcggatttcatgtacgaaaatgctaatttgtggtacaaaaatttggacaaactgattaaatacgtgaatgaagatggtcgtgtgaatgccttttattccacaccaaccatgtaccttgatgcacttcacaatgctaatcagacatgggagttaaagactgacgacttttttccatatgctgactgtccacactgttactggactggttatttcaccagccgaccagcaatcaagcgatatgtgaggctcaacaacaatttattgcaggtttgtaaacaactggaattggtaaatggccctgaaggaggcaacggtccatcttctgatactttacgccgagcaatggctgtggcccaacaccacgatgctgttactggtacagaaaaacaacatgtggctgatgattatgctaagcgacttgctattggtgccgttgaatgtcaggctttgataacagctgtcctgggaaaattcacagtgaaaaaaaccggtatccaacctcctgccatgacgttctgcgaccatcttaacataagcgtttgtgccgaaagtgaacaaaagaaagccttcacggtgacaatttacaacgccattgcgcggcaagtgagtgcgatgatccggcttccgttagcagatggctctatggctgtctatggaccgcagggacatccagttcaaagccaaattctccccatttcggatgctacaaaacaggtgcaaaaagaacagaatcaaggtcaaagcgtgtcgtcttttgagatcgtgtttaacgccgaacttccagccctgggctttgctacctatttcatcaattcgaccaagtcgtctcgtctaaaggaactattccgagaaccaccgaagaagcttaggaaagattccgaagaggtatcgattgaaaatgagtacatccaacttaccttttcttcggacagtggtcttttgacaagcatgacagataagagttctaaagtgacctccaaactgacccaaaatttttactggtaccgtggcagcgctgacaagaaacagccatctggtgcgtacatcttcagacccaatggcagtcaaccgattttgatctcgcagaaggtgacaaccaaactgtttaagggtcccctggtccaagagattcgacaggttatttcaccctttcttagtcaagtggtgaaggtgtatactggacagcggcatgccgagtttgaatacacagtggggcccattcccatcgcggataactggggaaaagagatcataagtcgtttcgacacggatattcagtccaatcaggtattcttcactgatgcgaatggaagagaaatgcaacaacgcaaggtgaattatcgacccacctggaaattgaacgtaacagagccagtggcaggcaattattatcccgtgaatagtcgaatgtacattaaagacagtaataagcagctgacgattctgactgaccgctcactgggtgggtcaagcctgaccagtggctctatggagatcatgcttcatagacgactgttggtagatgacaagagaggagtcaatgaaccgctaaacgagaccgggatctcgggaaagggtttgattgttcgtggcaaactatgcgtcattctggcgccaccccagtcctctgcagctctgcatcgtgaacttggagaaaagctgttattggaacccgtgctcgcttttgcgccgaacagcctcggtttcgaaaaatggacgaacctgtataactcactgcacggtggtcttaaacgtgaactaccgccgaacgttcaccttctgaccttggaaactgcgagggacttggccctgatccgcgtggagcatcagtatgaagttgacgaggatgctaagctatcacaacctgtgaacatttcattggcggagctgttcaccgattttgatatcgagtccatgacggaaatgaacctgtctgccaatcagctgatgaaggacaaacaacctcttcgctggaatattaaaaaaggaacgaaaatcgaaaagaagaagaaagagatgcctcgatcgccaactgatttaagtgtgcagcttagtccaatgcagatacgcacgttcaaggctgttattaaacgccattatggaaataaaatgcgctactag

Transcript

g12280.t1

ATGGCTGATCCTTCCAAGCGGTTTATTTACGTGGAAATCGCGTTTTTTGAGCGATGGTGGAACGAACAAAGTGAAGCCATGCGAGCAGATGTAAAGAAGCTTGTTTCCGAAAAGAGACTTGAGTTTATCAACGCAGGATGGTGTATGAACGATGAAGCAGCCACACATTACAATGGTATTATTGATCAAATGACTTATGGCTTAAACTTTGTCCAAGAAACATTTGGTTCCGATGCAAGGCCAAGGATAGCCTGGCATATTGATCCCTTCGGTCACTCGAATGAACAAGCCTCCATCTTCTCTCAAATGTCATTCGATGGATTCTTCTTTGGTCGCATCGATTACCAAGACAAAGATCTTCGTCTGGAGCAGCAGAGAATGGAACTGGTGTGGAGAGGAAGCAGAAGTTTAGCGCAAAAGTCGGACATTTTCACAGGCGTGCTTTACAATGGGTATAATCCGCCTAAAGGATTTTGCTATGATCAGTTTTGTGCAGATCCGCCTGTACAAGATGACCCAAACCTGTTTGACCTCAATGTCAAAGAAAGAGTTGCAAAATTTGTAGCCACAACTTGCAGCCAGGCTTTGCACTACAAAACCAACCACATAATGTTGACGATGGGATCGGATTTCATGTACGAAAATGCTAATTTGTGGTACAAAAATTTGGACAAACTGATTAAATACGTGAATGAAGATGGTCGTGTGAATGCCTTTTATTCCACACCAACCATGTACCTTGATGCACTTCACAATGCTAATCAGACATGGGAGTTAAAGACTGACGACTTTTTTCCATATGCTGACTGTCCACACTGTTACTGGACTGGTTATTTCACCAGCCGACCAGCAATCAAGCGATATGTGAGGCTCAACAACAATTTATTGCAGGTTTGTAAACAACTGGAATTGGTAAATGGCCCTGAAGGAGGCAACGGTCCATCTTCTGATACTTTACGCCGAGCAATGGCTGTGGCCCAACACCACGATGCTGTTACTGGTACAGAAAAACAACATGTGGCTGATGATTATGCTAAGCGACTTGCTATTGGTGCCGTTGAATGTCAGGCTTTGATAACAGCTGTCCTGGGAAAATTCACAGTGAAAAAAACCGGTATCCAACCTCCTGCCATGACGTTCTGCGACCATCTTAACATAAGCGTTTGTGCCGAAAGTGAACAAAAGAAAGCCTTCACGGTGACAATTTACAACGCCATTGCGCGGCAAGTGAGTGCGATGATCCGGCTTCCGTTAGCAGATGGCTCTATGGCTGTCTATGGACCGCAGGGACATCCAGTTCAAAGCCAAATTCTCCCCATTTCGGATGCTACAAAACAGGTGCAAAAAGAACAGAATCAAGGTCAAAGCGTGTCGTCTTTTGAGATCGTGTTTAACGCCGAACTTCCAGCCCTGggctttgctacctatttcatCAATTCGACCAAGTCGTCTCGTCTAAAGGAACTATTCCGAGAACCACCGAAGAAGCTTAGGAAAGATTCCGAAGAGGTATCGATTGAAAATGAGTACATCCAACTTACCTTTTCTTCGGACAGTGGTCTTTTGACAAGCATGACAGATAAGAGTTCTAAAGTGACCTCCAAACTGACCCAAAATTTTTACTGGTACCGTGGCAGCGCTGACAAGAAACAGCCATCTGGTGCGTACATCTTCAGACCCAATGGCAGTCAACCGATTTTGATCTCGCAGAAGGTGacaaccaaactgtttaagggTCCCCTGGTCCAAGAGATTCGACAGGTTATTTCACCCTTTCTTAGTCAAGTGGTGAAGGTGTATACTGGACAGCGGCATGCCGAGTTTGAATACACAGTGGGGCCCATTCCCATCGCGGATAACTGGGGAAAAGAGATCATAAGTCGTTTCGACACGGATATTCAGTCCAATCAGGTATTCTTCACTGATGCGAATGGAAGAGAAATGCAACAACGCAAGGTGAATTATCGACCCACCTGGAAATTGAACGTAACAGAGCCAGTGGCAGGCAATTATTATCCCGTGAATAGTCGAAtgtacattaaagacagtaatAAGCAGCTGACGATTCTGACTGACCGCTCACTGGGTGGGTCAAGCCTGACCAGTGGCTCTATGGAGATCATGCTTCATAGACGACTGTTGGTAGATGACAAGAGAGGAGTCAATGAACCGCTAAACGAGACCGGGATCTCGGGAAAGGGTTTGATTGTTCGTGGCAAACTATGCGTCATTCTGGCGCCACCCCAGTCCTCTGCAGCTCTGCATCGTGAACTTGGAGAAAAGCTGTTATTGGAACCCGTGCTCGCTTTTGCGCCGAACAGCCTCGGTTTCGAAAAATGGACGAACCTGTATAACTCACTGCACGGTGGTCTTAAACGTGAACTACCGCCGAACGTTCACCTTCTGACCTTGGAAACTGCGAGGGACTTGGCCCTGATCCGCGTGGAGCATCAGTATGAAGTTGACGAGGATGCTAAGCTATCACAACCTGTGAACATTTCATTGGCGGAGCTGTTCACCGATTTTGATATCGAGTCCATGACGGAAATGAACCTGTCTGCCAATCAGCTGATGAAGGACAAACAACCTCTTCGCTGGAATATTAAAAAAGGAACGAAAAtcgaaaagaagaagaaagagatgCCTCGATCGCCAACTGATTTAAGTGTGCAGCTTAGTCCAATGCAGATACGCACGTTCAAGGCTGTTATTAAACGCCATTATGGAAATAAAATGCGCTACTAG

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q60HE9	Lysosomal alpha-mannosidase OS=Macaca fascicularis OX=9541 GN=MAN2B1 PE=2 SV=1
O00754	Lysosomal alpha-mannosidase OS=Homo sapiens OX=9606 GN=MAN2B1 PE=1 SV=3
Q8VHC8	Lysosomal alpha-mannosidase OS=Cavia porcellus OX=10141 GN=MAN2B1 PE=1 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0002052 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF07748 all species →	Glyco_hydro_38C	Glycosyl hydrolases family 38 C-terminal domain	Domain	Interproscan
PF09261 all species →	Alpha-mann_mid	Alpha mannosidase middle domain	Domain	Interproscan
PF21260 all species →	Laman-like_dom	Lysosomal alpha-mannosidase-like, central domain	Domain	Interproscan
PF01074 all species →	Glyco_hydro_38N	Glycosyl hydrolases family 38 N-terminal domain	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR037094 all species →	Homologous_superfamily	Glycoside hydrolase family 38, central domain superfamily	Interproscan
IPR011013 all species →	Homologous_superfamily	Galactose mutarotase-like domain superfamily	Interproscan
IPR011682 all species →	Domain	Glycosyl hydrolase family 38, C-terminal	Interproscan
IPR015341 all species →	Domain	Glycoside hydrolase family 38, central domain	Interproscan
IPR050843 all species →	Family	Glycosyl Hydrolase Family 38	Interproscan
IPR011330 all species →	Homologous_superfamily	Glycoside hydrolase/deacetylase, beta/alpha-barrel	Interproscan
IPR048534 all species →	Domain	Lysosomal alpha-mannosidase-like, central domain	Interproscan
IPR027291 all species →	Homologous_superfamily	Glycoside hydrolase 38, N-terminal domain superfamily	Interproscan
IPR013780 all species →	Homologous_superfamily	Glycosyl hydrolase, all-beta	Interproscan
IPR028995 all species →	Homologous_superfamily	Glycoside hydrolase families 57/38, central domain superfamily	Interproscan
IPR000602 all species →	Domain	Glycoside hydrolase family 38, N-terminal domain	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR11607 all species →	ALPHA-MANNOSIDASE	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0004559 all species →	Molecular Function	alpha-mannosidase activity	Interproscan
GO:0006013 all species →	Biological Process	mannose metabolic process	Interproscan
GO:0003824 all species →	Molecular Function	catalytic activity	Interproscan
GO:0005975 all species →	Biological Process	carbohydrate metabolic process	Interproscan
GO:0030246 all species →	Molecular Function	carbohydrate binding	Interproscan
GO:0005764 all species →	Cellular Component	lysosome	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K12311	MAN2B1, LAMAN; lysosomal alpha-mannosidase	EC:3.2.1.24	Lysosome	ko04142	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of g12280.t1 across 48 RNA-seq samples of Montipora capitata. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

48Samples

48TPM > 0

3Conditions

89.1Max TPM

42.3Mean TPM

By condition

Condition	Samples	TPM > 0	Mean TPM	Max TPM
whole organisms · ambient pH treatment	21	21	40.67	86.09
whole organisms · low pH treatment	15	15	41.10	89.06
whole organisms · extra low pH treatment pH treatment	12	12	46.58	82.96

Per sample · hover a bar for the full sample record · show / hide the sample table

SRA run	Condition	Tissue	Developmental stage	Treatment	Study	TPM
SRR11452251	whole organisms · ambient pH treatment	whole organisms	egg	ambient pH treatment	SRP254626	86.09
SRR11452217	whole organisms · ambient pH treatment	whole organisms	fertilized embryo	ambient pH treatment	SRP254626	74.06
SRR11452263	whole organisms · ambient pH treatment	whole organisms	egg	ambient pH treatment	SRP254626	67.17
SRR11452222	whole organisms · ambient pH treatment	whole organisms	planulae	ambient pH treatment	SRP254626	63.24
SRR11452228	whole organisms · ambient pH treatment	whole organisms	planulae	ambient pH treatment	SRP254626	62.56
SRR11452230	whole organisms · ambient pH treatment	whole organisms	planulae	ambient pH treatment	SRP254626	59.29
SRR11452240	whole organisms · ambient pH treatment	whole organisms	fertilized embryo	ambient pH treatment	SRP254626	57.81
SRR11452262	whole organisms · ambient pH treatment	whole organisms	egg	ambient pH treatment	SRP254626	57.22
SRR11452232	whole organisms · ambient pH treatment	whole organisms	blastula	ambient pH treatment	SRP254626	35.90
SRR11452231	whole organisms · ambient pH treatment	whole organisms	blastula	ambient pH treatment	SRP254626	35.35
SRR11452254	whole organisms · ambient pH treatment	whole organisms	cleavage	ambient pH treatment	SRP254626	34.45
SRR11452260	whole organisms · ambient pH treatment	whole organisms	cleavage	ambient pH treatment	SRP254626	32.45
SRR11452234	whole organisms · ambient pH treatment	whole organisms	morula	ambient pH treatment	SRP254626	23.56
SRR11452246	whole organisms · ambient pH treatment	whole organisms	prawn chip	ambient pH treatment	SRP254626	23.09
SRR11452252	whole organisms · ambient pH treatment	whole organisms	prawn chip	ambient pH treatment	SRP254626	21.79
SRR11452242	whole organisms · ambient pH treatment	whole organisms	gastrula	ambient pH treatment	SRP254626	21.57
SRR11452237	whole organisms · ambient pH treatment	whole organisms	gastrula	ambient pH treatment	SRP254626	20.40
SRR11452259	whole organisms · ambient pH treatment	whole organisms	cleavage	ambient pH treatment	SRP254626	20.14
SRR11452250	whole organisms · ambient pH treatment	whole organisms	prawn chip	ambient pH treatment	SRP254626	20.13
SRR11452243	whole organisms · ambient pH treatment	whole organisms	gastrula	ambient pH treatment	SRP254626	18.99
SRR11452233	whole organisms · ambient pH treatment	whole organisms	morula	ambient pH treatment	SRP254626	18.79
SRR11452229	whole organisms · low pH treatment	whole organisms	fertilized embryo	low pH treatment	SRP254626	89.06
SRR11452216	whole organisms · low pH treatment	whole organisms	fertilized embryo	low pH treatment	SRP254626	63.92
SRR11452221	whole organisms · low pH treatment	whole organisms	planulae	low pH treatment	SRP254626	62.20
SRR11452218	whole organisms · low pH treatment	whole organisms	fertilized embryo	low pH treatment	SRP254626	61.27
SRR11452223	whole organisms · low pH treatment	whole organisms	planulae	low pH treatment	SRP254626	60.62
SRR11452224	whole organisms · low pH treatment	whole organisms	planulae	low pH treatment	SRP254626	56.67
SRR11452255	whole organisms · low pH treatment	whole organisms	cleavage	low pH treatment	SRP254626	38.43
SRR11452253	whole organisms · low pH treatment	whole organisms	cleavage	low pH treatment	SRP254626	33.83
SRR11452245	whole organisms · low pH treatment	whole organisms	prawn chip	low pH treatment	SRP254626	23.73
SRR11452238	whole organisms · low pH treatment	whole organisms	gastrula	low pH treatment	SRP254626	23.08
SRR11452236	whole organisms · low pH treatment	whole organisms	gastrula	low pH treatment	SRP254626	22.52
SRR11452258	whole organisms · low pH treatment	whole organisms	cleavage	low pH treatment	SRP254626	20.87
SRR11452247	whole organisms · low pH treatment	whole organisms	prawn chip	low pH treatment	SRP254626	20.77
SRR11452241	whole organisms · low pH treatment	whole organisms	gastrula	low pH treatment	SRP254626	20.38
SRR11452249	whole organisms · low pH treatment	whole organisms	prawn chip	low pH treatment	SRP254626	19.19
SRR11452220	whole organisms · extra low pH treatment pH treatment	whole organisms	fertilized embryo	extra low pH treatment pH treatment	SRP254626	82.96
SRR11452219	whole organisms · extra low pH treatment pH treatment	whole organisms	fertilized embryo	extra low pH treatment pH treatment	SRP254626	78.64
SRR11452227	whole organisms · extra low pH treatment pH treatment	whole organisms	planulae	extra low pH treatment pH treatment	SRP254626	69.31
SRR11452225	whole organisms · extra low pH treatment pH treatment	whole organisms	planulae	extra low pH treatment pH treatment	SRP254626	63.63
SRR11452226	whole organisms · extra low pH treatment pH treatment	whole organisms	planulae	extra low pH treatment pH treatment	SRP254626	60.16
SRR11452261	whole organisms · extra low pH treatment pH treatment	whole organisms	fertilized embryo	extra low pH treatment pH treatment	SRP254626	54.49
SRR11452256	whole organisms · extra low pH treatment pH treatment	whole organisms	cleavage	extra low pH treatment pH treatment	SRP254626	35.20
SRR11452257	whole organisms · extra low pH treatment pH treatment	whole organisms	cleavage	extra low pH treatment pH treatment	SRP254626	33.36
SRR11452235	whole organisms · extra low pH treatment pH treatment	whole organisms	gastrula	extra low pH treatment pH treatment	SRP254626	23.43
SRR11452239	whole organisms · extra low pH treatment pH treatment	whole organisms	gastrula	extra low pH treatment pH treatment	SRP254626	21.29
SRR11452244	whole organisms · extra low pH treatment pH treatment	whole organisms	prawn chip	extra low pH treatment pH treatment	SRP254626	18.42
SRR11452248	whole organisms · extra low pH treatment pH treatment	whole organisms	prawn chip	extra low pH treatment pH treatment	SRP254626	18.13

Source: CnidoSite RNA-seq expression matrices (MCAPI_TPM, StringTie quantification over 48 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.