Gene detail

Detailed information of g1240.t1 in Calvadosia cruxmelitensis

Genomic Location: not available for this species
NR annotation: XP_020615249.1, eIF-2-alpha kinase GCN2-like [Orbicella faveolata]
Species Calvadosia cruxmelitensis · all data for this species · gene families

Sequence

Sequence data are not available for Calvadosia cruxmelitensis.
Nucleotide and protein sequences are provided for the species whose genome annotation is complete (see annotated genomes); for this species only the assembly is archived. The functional annotation below is likewise unavailable.

UniProt (Swiss-Prot top hit)

UniProt accession	Description
D4A7V9	eIF-2-alpha kinase GCN2 OS=Rattus norvegicus OX=10116 GN=Eif2ak4 PE=3 SV=2
Q9P2K8	eIF-2-alpha kinase GCN2 OS=Homo sapiens OX=9606 GN=EIF2AK4 PE=1 SV=3
Q9QZ05	eIF-2-alpha kinase GCN2 OS=Mus musculus OX=10090 GN=Eif2ak4 PE=1 SV=2

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0000000 (this species only)
Orthogroup (gene family)	OG0000011 (this species only)
Orthogroup (gene family)	OG0000122 (this species only)
Orthogroup (gene family)	OG0000328 (this species only)
Orthogroup (gene family)	OG0001359 (this species only)
Orthogroup (gene family)	OG0002183 (this species only)
Orthogroup (gene family)	OG0002825 (this species only)
Orthogroup (gene family)	OG0003294 (this species only)
Orthogroup (gene family)	OG0004514 (this species only)
Orthogroup (gene family)	OG0005179 (this species only)
Orthogroup (gene family)	OG0008066 (this species only)
Orthogroup (gene family)	OG0009781 (this species only)
Orthogroup (gene family)	OG0021357 (this species only)
Orthogroup (gene family)	OG0048332 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF00041 all species →	fn3	Fibronectin type III domain	Domain	Interproscan
PF05773 all species →	RWD	RWD domain	Domain	Interproscan
PF12745 all species →	HGTP_anticodon2	Anticodon binding domain of tRNAs	Domain	Interproscan
PF13393 all species →	tRNA-synt_His	Histidyl-tRNA synthetase	Domain	Interproscan
PF00069 all species →	Pkinase	Protein kinase domain	Domain	Interproscan
PF20741 all species →	GKRP-like_C	C-terminal lid domain of glucokinase regulatory protein	Domain	Interproscan
PF00535 all species →	Glycos_transf_2	Glycosyl transferase family 2	Family	Interproscan
PF16158 all species →	N_BRCA1_IG	Ig-like domain from next to BRCA1 gene	Domain	Interproscan
PF13499 all species →	EF-hand_7	EF-hand domain pair	Domain	Interproscan
PF00264 all species →	Tyrosinase	Common central domain of tyrosinase	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR016024 all species →	Homologous_superfamily	Armadillo-type fold	Interproscan
IPR003961 all species →	Domain	Fibronectin type III	Interproscan
IPR013783 all species →	Homologous_superfamily	Immunoglobulin-like fold	Interproscan
IPR050991 all species →	Family	Extracellular Matrix Regulatory Proteins	Interproscan
IPR036116 all species →	Homologous_superfamily	Fibronectin type III superfamily	Interproscan
IPR011989 all species →	Homologous_superfamily	Armadillo-like helical	Interproscan
IPR000719 all species →	Domain	Protein kinase domain	Interproscan
IPR050339 all species →	Family	Cell Cycle and Stress Response Kinase	Interproscan
IPR006575 all species →	Domain	RWD domain	Interproscan
IPR016135 all species →	Homologous_superfamily	Ubiquitin-conjugating enzyme/RWD-like	Interproscan
IPR008266 all species →	Active_site	Tyrosine-protein kinase, active site	Interproscan
IPR024435 all species →	Domain	Histidyl tRNA synthetase-related domain	Interproscan
IPR008271 all species →	Active_site	Serine/threonine-protein kinase, active site	Interproscan
IPR020635 all species →	Domain	Tyrosine-protein kinase, catalytic domain	Interproscan
IPR011009 all species →	Homologous_superfamily	Protein kinase-like domain superfamily	Interproscan
IPR045864 all species →	Homologous_superfamily	Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL)	Interproscan
IPR017441 all species →	Binding_site	Protein kinase, ATP binding site	Interproscan
IPR036621 all species →	Homologous_superfamily	Anticodon-binding domain superfamily	Interproscan
IPR041715 all species →	Domain	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain	Interproscan
IPR016255 all species →	Family	eIF-2-alpha kinase Gcn2	Interproscan
IPR046348 all species →	Homologous_superfamily	SIS domain superfamily	Interproscan
IPR001347 all species →	Domain	SIS domain	Interproscan
IPR040190 all species →	Family	N-acetylmuramic acid 6-phosphate etherase/glucokinase regulatory protein	Interproscan
IPR007265 all species →	Family	Conserved oligomeric Golgi complex, subunit 3	Interproscan
IPR029044 all species →	Homologous_superfamily	Nucleotide-diphospho-sugar transferases	Interproscan
IPR001173 all species →	Domain	Glycosyltransferase 2-like	Interproscan
IPR032350 all species →	Domain	Next to BRCA1, central domain	Interproscan
IPR040415 all species →	Family	SET domain-containing protein 9	Interproscan
IPR046341 all species →	Homologous_superfamily	SET domain superfamily	Interproscan
IPR001214 all species →	Domain	SET domain	Interproscan
IPR002048 all species →	Domain	EF-hand domain	Interproscan
IPR011992 all species →	Homologous_superfamily	EF-hand domain pair	Interproscan
IPR018247 all species →	Binding_site	EF-Hand 1, calcium-binding site	Interproscan
IPR008922 all species →	Homologous_superfamily	Di-copper centre-containing domain superfamily	Interproscan
IPR036465 all species →	Homologous_superfamily	von Willebrand factor A-like domain superfamily	Interproscan
IPR002227 all species →	Domain	Tyrosinase copper-binding domain	Interproscan
IPR036397 all species →	Homologous_superfamily	Ribonuclease H superfamily	Interproscan
IPR012337 all species →	Homologous_superfamily	Ribonuclease H-like superfamily	Interproscan
IPR001584 all species →	Domain	Integrase, catalytic core	Interproscan
IPR050951 all species →	Family	Retrovirus-related Pol polyprotein	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR46708 all species →	TENASCIN	Interproscan
PTHR47331 all species →	PHD-TYPE DOMAIN-CONTAINING PROTEIN	Interproscan
PTHR11042 all species →	EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE EIF2-ALPHA KINASE -RELATED	Interproscan
PTHR10088 all species →	GLUCOKINASE REGULATORY PROTEIN	Interproscan
PTHR13302 all species →	CONSERVED OLIGOMERIC GOLGI COMPLEX COMPONENT 3	Interproscan
PTHR11675 all species →	N-ACETYLGALACTOSAMINYLTRANSFERASE	Interproscan
PTHR33524 all species →	C5ORF35	Interproscan
PTHR37984 all species →	PROTEIN CBG26694	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0005515 all species →	Molecular Function	protein binding	Interproscan
GO:0004672 all species →	Molecular Function	protein kinase activity	Interproscan
GO:0005524 all species →	Molecular Function	ATP binding	Interproscan
GO:0006468 all species →	Biological Process	protein phosphorylation	Interproscan
GO:0004694 all species →	Molecular Function	eukaryotic translation initiation factor 2alpha kinase activity	Interproscan
GO:0005634 all species →	Cellular Component	nucleus	Interproscan
GO:0005737 all species →	Cellular Component	cytoplasm	Interproscan
GO:0004713 all species →	Molecular Function	protein tyrosine kinase activity	Interproscan
GO:0000077 all species →	Biological Process	DNA damage checkpoint signaling	Interproscan
GO:0010998 all species →	Biological Process	regulation of translational initiation by eIF2 alpha phosphorylation	Interproscan
GO:0097367 all species →	Molecular Function	carbohydrate derivative binding	Interproscan
GO:1901135 all species →	Biological Process	carbohydrate derivative metabolic process	Interproscan
GO:0004857 all species →	Molecular Function	enzyme inhibitor activity	Interproscan
GO:0005654 all species →	Cellular Component	nucleoplasm	Interproscan
GO:0005829 all species →	Cellular Component	cytosol	Interproscan
GO:0009750 all species →	Biological Process	response to fructose	Interproscan
GO:0019899 all species →	Molecular Function	enzyme binding	Interproscan
GO:0030246 all species →	Molecular Function	carbohydrate binding	Interproscan
GO:0033132 all species →	Biological Process	negative regulation of glucokinase activity	Interproscan
GO:0042593 all species →	Biological Process	glucose homeostasis	Interproscan
GO:0070095 all species →	Molecular Function	fructose-6-phosphate binding	Interproscan
GO:0005801 all species →	Cellular Component	cis-Golgi network	Interproscan
GO:0006886 all species →	Biological Process	intracellular protein transport	Interproscan
GO:0006891 all species →	Biological Process	intra-Golgi vesicle-mediated transport	Interproscan
GO:0007030 all species →	Biological Process	Golgi organization	Interproscan
GO:0016020 all species →	Cellular Component	membrane	Interproscan
GO:0017119 all species →	Cellular Component	Golgi transport complex	Interproscan
GO:0004653 all species →	Molecular Function	polypeptide N-acetylgalactosaminyltransferase activity	Interproscan
GO:0005794 all species →	Cellular Component	Golgi apparatus	Interproscan
GO:0006493 all species →	Biological Process	protein O-linked glycosylation	Interproscan
GO:0005509 all species →	Molecular Function	calcium ion binding	Interproscan
GO:0016491 all species →	Molecular Function	oxidoreductase activity	Interproscan
GO:0003676 all species →	Molecular Function	nucleic acid binding	Interproscan
GO:0015074 all species →	Biological Process	DNA integration	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K16196	EIF2AK4; eukaryotic translation initiation factor 2-alpha kinase 4	EC:2.7.11.1	Protein kinases	ko01001	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.