Genomic Location: :...
NR annotation: XP_020615249.1, eIF-2-alpha kinase GCN2-like [Orbicella faveolata]
| CDS | |||||
| Transcript |
| Protein |
| Uniprot term | Description |
|---|---|
| D4A7V9 | eIF-2-alpha kinase GCN2 OS=Rattus norvegicus OX=10116 GN=Eif2ak4 PE=3 SV=2 |
| Q9P2K8 | eIF-2-alpha kinase GCN2 OS=Homo sapiens OX=9606 GN=EIF2AK4 PE=1 SV=3 |
| Q9QZ05 | eIF-2-alpha kinase GCN2 OS=Mus musculus OX=10090 GN=Eif2ak4 PE=1 SV=2 |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF00041 | fn3 | Fibronectin type III domain | Domain | Interproscan |
| PF05773 | RWD | RWD domain | Domain | Interproscan |
| PF12745 | HGTP_anticodon2 | Anticodon binding domain of tRNAs | Domain | Interproscan |
| PF13393 | tRNA-synt_His | Histidyl-tRNA synthetase | Domain | Interproscan |
| PF00069 | Pkinase | Protein kinase domain | Domain | Interproscan |
| PF20741 | GKRP-like_C | C-terminal lid domain of glucokinase regulatory protein | Domain | Interproscan |
| PF00535 | Glycos_transf_2 | Glycosyl transferase family 2 | Family | Interproscan |
| PF16158 | N_BRCA1_IG | Ig-like domain from next to BRCA1 gene | Domain | Interproscan |
| PF13499 | EF-hand_7 | EF-hand domain pair | Domain | Interproscan |
| PF00264 | Tyrosinase | Common central domain of tyrosinase | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR016024 | Homologous_superfamily | Armadillo-type fold | Interproscan |
| IPR003961 | Domain | Fibronectin type III | Interproscan |
| IPR013783 | Homologous_superfamily | Immunoglobulin-like fold | Interproscan |
| IPR050991 | Family | Extracellular Matrix Regulatory Proteins | Interproscan |
| IPR036116 | Homologous_superfamily | Fibronectin type III superfamily | Interproscan |
| IPR011989 | Homologous_superfamily | Armadillo-like helical | Interproscan |
| IPR000719 | Domain | Protein kinase domain | Interproscan |
| IPR050339 | Family | Cell Cycle and Stress Response Kinase | Interproscan |
| IPR006575 | Domain | RWD domain | Interproscan |
| IPR016135 | Homologous_superfamily | Ubiquitin-conjugating enzyme/RWD-like | Interproscan |
| IPR008266 | Active_site | Tyrosine-protein kinase, active site | Interproscan |
| IPR024435 | Domain | Histidyl tRNA synthetase-related domain | Interproscan |
| IPR008271 | Active_site | Serine/threonine-protein kinase, active site | Interproscan |
| IPR020635 | Domain | Tyrosine-protein kinase, catalytic domain | Interproscan |
| IPR011009 | Homologous_superfamily | Protein kinase-like domain superfamily | Interproscan |
| IPR045864 | Homologous_superfamily | Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL) | Interproscan |
| IPR017441 | Binding_site | Protein kinase, ATP binding site | Interproscan |
| IPR036621 | Homologous_superfamily | Anticodon-binding domain superfamily | Interproscan |
| IPR041715 | Domain | Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain | Interproscan |
| IPR016255 | Family | eIF-2-alpha kinase Gcn2 | Interproscan |
| IPR046348 | Homologous_superfamily | SIS domain superfamily | Interproscan |
| IPR001347 | Domain | SIS domain | Interproscan |
| IPR040190 | Family | N-acetylmuramic acid 6-phosphate etherase/glucokinase regulatory protein | Interproscan |
| IPR007265 | Family | Conserved oligomeric Golgi complex, subunit 3 | Interproscan |
| IPR029044 | Homologous_superfamily | Nucleotide-diphospho-sugar transferases | Interproscan |
| IPR001173 | Domain | Glycosyltransferase 2-like | Interproscan |
| IPR032350 | Domain | Next to BRCA1, central domain | Interproscan |
| IPR040415 | Family | SET domain-containing protein 9 | Interproscan |
| IPR046341 | Homologous_superfamily | SET domain superfamily | Interproscan |
| IPR001214 | Domain | SET domain | Interproscan |
| IPR002048 | Domain | EF-hand domain | Interproscan |
| IPR011992 | Homologous_superfamily | EF-hand domain pair | Interproscan |
| IPR018247 | Binding_site | EF-Hand 1, calcium-binding site | Interproscan |
| IPR008922 | Homologous_superfamily | Di-copper centre-containing domain superfamily | Interproscan |
| IPR036465 | Homologous_superfamily | von Willebrand factor A-like domain superfamily | Interproscan |
| IPR002227 | Domain | Tyrosinase copper-binding domain | Interproscan |
| IPR036397 | Homologous_superfamily | Ribonuclease H superfamily | Interproscan |
| IPR012337 | Homologous_superfamily | Ribonuclease H-like superfamily | Interproscan |
| IPR001584 | Domain | Integrase, catalytic core | Interproscan |
| IPR050951 | Family | Retrovirus-related Pol polyprotein | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR46708 | TENASCIN | Interproscan |
| PTHR47331 | PHD-TYPE DOMAIN-CONTAINING PROTEIN | Interproscan |
| PTHR11042 | EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE EIF2-ALPHA KINASE -RELATED | Interproscan |
| PTHR10088 | GLUCOKINASE REGULATORY PROTEIN | Interproscan |
| PTHR13302 | CONSERVED OLIGOMERIC GOLGI COMPLEX COMPONENT 3 | Interproscan |
| PTHR11675 | N-ACETYLGALACTOSAMINYLTRANSFERASE | Interproscan |
| PTHR33524 | C5ORF35 | Interproscan |
| PTHR37984 | PROTEIN CBG26694 | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0005515 | Molecular Function | protein binding | Interproscan |
| GO:0004672 | Molecular Function | protein kinase activity | Interproscan |
| GO:0005524 | Molecular Function | ATP binding | Interproscan |
| GO:0006468 | Biological Process | protein phosphorylation | Interproscan |
| GO:0004694 | Molecular Function | eukaryotic translation initiation factor 2alpha kinase activity | Interproscan |
| GO:0005634 | Cellular Component | nucleus | Interproscan |
| GO:0005737 | Cellular Component | cytoplasm | Interproscan |
| GO:0004713 | Molecular Function | protein tyrosine kinase activity | Interproscan |
| GO:0000077 | Biological Process | DNA damage checkpoint signaling | Interproscan |
| GO:0010998 | Biological Process | regulation of translational initiation by eIF2 alpha phosphorylation | Interproscan |
| GO:0097367 | Molecular Function | carbohydrate derivative binding | Interproscan |
| GO:1901135 | Biological Process | carbohydrate derivative metabolic process | Interproscan |
| GO:0004857 | Molecular Function | enzyme inhibitor activity | Interproscan |
| GO:0005654 | Cellular Component | nucleoplasm | Interproscan |
| GO:0005829 | Cellular Component | cytosol | Interproscan |
| GO:0009750 | Biological Process | response to fructose | Interproscan |
| GO:0019899 | Molecular Function | enzyme binding | Interproscan |
| GO:0030246 | Molecular Function | carbohydrate binding | Interproscan |
| GO:0033132 | Biological Process | negative regulation of glucokinase activity | Interproscan |
| GO:0042593 | Biological Process | glucose homeostasis | Interproscan |
| GO:0070095 | Molecular Function | fructose-6-phosphate binding | Interproscan |
| GO:0005801 | Cellular Component | cis-Golgi network | Interproscan |
| GO:0006886 | Biological Process | intracellular protein transport | Interproscan |
| GO:0006891 | Biological Process | intra-Golgi vesicle-mediated transport | Interproscan |
| GO:0007030 | Biological Process | Golgi organization | Interproscan |
| GO:0016020 | Cellular Component | membrane | Interproscan |
| GO:0017119 | Cellular Component | Golgi transport complex | Interproscan |
| GO:0004653 | Molecular Function | polypeptide N-acetylgalactosaminyltransferase activity | Interproscan |
| GO:0005794 | Cellular Component | Golgi apparatus | Interproscan |
| GO:0006493 | Biological Process | protein O-linked glycosylation | Interproscan |
| GO:0005509 | Molecular Function | calcium ion binding | Interproscan |
| GO:0016491 | Molecular Function | oxidoreductase activity | Interproscan |
| GO:0003676 | Molecular Function | nucleic acid binding | Interproscan |
| GO:0015074 | Biological Process | DNA integration | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K16196 | EIF2AK4; eukaryotic translation initiation factor 2-alpha kinase 4 | EC:2.7.11.1 | Protein kinases | ko01001 | deepkoala |