Detailed information of g12476.t1 in Montipora capitata

Genomic Location: Sc0000401:229615...239779
NR annotation: XP_029201510.2, rho GTPase-activating protein 18-like isoform X3 [Acropora millepora]
Species Montipora capitata · all data for this species · gene families


 Gene Structure
More details in JBrowse  Sequence
CDS
Transcript
Protein
 UniProt (Swiss-Prot top hit)
UniProt accessionDescription
Q8K0Q5Rho GTPase-activating protein 18 OS=Mus musculus OX=10090 GN=Arhgap18 PE=1 SV=1
Q8N392Rho GTPase-activating protein 18 OS=Homo sapiens OX=9606 GN=ARHGAP18 PE=1 SV=3
Q9P2N2Rho GTPase-activating protein 28 OS=Homo sapiens OX=9606 GN=ARHGAP28 PE=1 SV=3
 Gene family
Family typeMembership / link
Orthogroup (gene family)OG0002558 (this species only) · gene tree & orthology

 Pfam domain
Pfam accessionPfam nameDescriptionTypeSource
PF00620
all species →		RhoGAPRhoGAP domainDomainInterproscan

 InterPro
InterPro termTypeDescriptionSource
IPR000198
all species →		DomainRho GTPase-activating protein domainInterproscan
IPR008936
all species →		Homologous_superfamilyRho GTPase activation proteinInterproscan

 PANTHER
PANTHER termDescriptionSource
PTHR14963
all species →		RHO GTPASE ACTIVATING PROTEIN 18,19-RELATEDInterproscan

 Gene Ontology
GO termCategoryDescriptionSource
GO:0007165
all species →		Biological Processsignal transductionInterproscan
GO:0005096
all species →		Molecular FunctionGTPase activator activityInterproscan
GO:0005737
all species →		Cellular ComponentcytoplasmInterproscan
GO:0030833
all species →		Biological Processregulation of actin filament polymerizationInterproscan
GO:0051056
all species →		Biological Processregulation of small GTPase mediated signal transductionInterproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.
 KEGG pathway
No KEGG orthology assignment for g12476.t1.

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of g12476.t1 across 48 RNA-seq samples of Montipora capitata. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

48Samples
48TPM > 0
3Conditions
418.1Max TPM
184.9Mean TPM

By condition

ConditionSamplesTPM > 0 Mean TPMMax TPMMean, relative to max
whole organisms · ambient pH treatment 21 21 185.59 418.07
whole organisms · low pH treatment 15 15 187.54 346.57
whole organisms · extra low pH treatment pH treatment 12 12 180.41 328.31

Per sample · hover a bar for the full sample record

Show the sample table (48 samples)
SRA runConditionTissueDevelopmental stage TreatmentStudyTPM
SRR11452263 whole organisms · ambient pH treatment whole organisms egg ambient pH treatment SRP254626 418.07
SRR11452262 whole organisms · ambient pH treatment whole organisms egg ambient pH treatment SRP254626 393.11
SRR11452251 whole organisms · ambient pH treatment whole organisms egg ambient pH treatment SRP254626 328.96
SRR11452240 whole organisms · ambient pH treatment whole organisms fertilized embryo ambient pH treatment SRP254626 317.43
SRR11452217 whole organisms · ambient pH treatment whole organisms fertilized embryo ambient pH treatment SRP254626 278.67
SRR11452254 whole organisms · ambient pH treatment whole organisms cleavage ambient pH treatment SRP254626 245.05
SRR11452259 whole organisms · ambient pH treatment whole organisms cleavage ambient pH treatment SRP254626 233.23
SRR11452260 whole organisms · ambient pH treatment whole organisms cleavage ambient pH treatment SRP254626 232.95
SRR11452250 whole organisms · ambient pH treatment whole organisms prawn chip ambient pH treatment SRP254626 211.43
SRR11452252 whole organisms · ambient pH treatment whole organisms prawn chip ambient pH treatment SRP254626 206.19
SRR11452246 whole organisms · ambient pH treatment whole organisms prawn chip ambient pH treatment SRP254626 200.60
SRR11452234 whole organisms · ambient pH treatment whole organisms morula ambient pH treatment SRP254626 103.75
SRR11452230 whole organisms · ambient pH treatment whole organisms planulae ambient pH treatment SRP254626 96.54
SRR11452233 whole organisms · ambient pH treatment whole organisms morula ambient pH treatment SRP254626 94.20
SRR11452222 whole organisms · ambient pH treatment whole organisms planulae ambient pH treatment SRP254626 93.56
SRR11452232 whole organisms · ambient pH treatment whole organisms blastula ambient pH treatment SRP254626 89.99
SRR11452228 whole organisms · ambient pH treatment whole organisms planulae ambient pH treatment SRP254626 88.08
SRR11452242 whole organisms · ambient pH treatment whole organisms gastrula ambient pH treatment SRP254626 83.34
SRR11452237 whole organisms · ambient pH treatment whole organisms gastrula ambient pH treatment SRP254626 72.41
SRR11452243 whole organisms · ambient pH treatment whole organisms gastrula ambient pH treatment SRP254626 69.35
SRR11452231 whole organisms · ambient pH treatment whole organisms blastula ambient pH treatment SRP254626 40.46
SRR11452229 whole organisms · low pH treatment whole organisms fertilized embryo low pH treatment SRP254626 346.57
SRR11452218 whole organisms · low pH treatment whole organisms fertilized embryo low pH treatment SRP254626 336.78
SRR11452255 whole organisms · low pH treatment whole organisms cleavage low pH treatment SRP254626 297.19
SRR11452216 whole organisms · low pH treatment whole organisms fertilized embryo low pH treatment SRP254626 270.22
SRR11452253 whole organisms · low pH treatment whole organisms cleavage low pH treatment SRP254626 260.50
SRR11452247 whole organisms · low pH treatment whole organisms prawn chip low pH treatment SRP254626 227.56
SRR11452249 whole organisms · low pH treatment whole organisms prawn chip low pH treatment SRP254626 213.97
SRR11452258 whole organisms · low pH treatment whole organisms cleavage low pH treatment SRP254626 204.06
SRR11452245 whole organisms · low pH treatment whole organisms prawn chip low pH treatment SRP254626 197.83
SRR11452223 whole organisms · low pH treatment whole organisms planulae low pH treatment SRP254626 83.72
SRR11452238 whole organisms · low pH treatment whole organisms gastrula low pH treatment SRP254626 78.80
SRR11452241 whole organisms · low pH treatment whole organisms gastrula low pH treatment SRP254626 78.79
SRR11452236 whole organisms · low pH treatment whole organisms gastrula low pH treatment SRP254626 76.95
SRR11452224 whole organisms · low pH treatment whole organisms planulae low pH treatment SRP254626 75.41
SRR11452221 whole organisms · low pH treatment whole organisms planulae low pH treatment SRP254626 64.74
SRR11452219 whole organisms · extra low pH treatment pH treatment whole organisms fertilized embryo extra low pH treatment pH treatment SRP254626 328.31
SRR11452261 whole organisms · extra low pH treatment pH treatment whole organisms fertilized embryo extra low pH treatment pH treatment SRP254626 298.11
SRR11452256 whole organisms · extra low pH treatment pH treatment whole organisms cleavage extra low pH treatment pH treatment SRP254626 248.62
SRR11452257 whole organisms · extra low pH treatment pH treatment whole organisms cleavage extra low pH treatment pH treatment SRP254626 247.19
SRR11452220 whole organisms · extra low pH treatment pH treatment whole organisms fertilized embryo extra low pH treatment pH treatment SRP254626 233.98
SRR11452248 whole organisms · extra low pH treatment pH treatment whole organisms prawn chip extra low pH treatment pH treatment SRP254626 213.70
SRR11452244 whole organisms · extra low pH treatment pH treatment whole organisms prawn chip extra low pH treatment pH treatment SRP254626 184.50
SRR11452225 whole organisms · extra low pH treatment pH treatment whole organisms planulae extra low pH treatment pH treatment SRP254626 91.67
SRR11452239 whole organisms · extra low pH treatment pH treatment whole organisms gastrula extra low pH treatment pH treatment SRP254626 88.27
SRR11452227 whole organisms · extra low pH treatment pH treatment whole organisms planulae extra low pH treatment pH treatment SRP254626 86.16
SRR11452235 whole organisms · extra low pH treatment pH treatment whole organisms gastrula extra low pH treatment pH treatment SRP254626 72.24
SRR11452226 whole organisms · extra low pH treatment pH treatment whole organisms planulae extra low pH treatment pH treatment SRP254626 72.14

Source: CnidoSite RNA-seq expression matrices (MCAPI_TPM, StringTie quantification over 48 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.

Co-expression network

Genes whose expression across the transcriptome samples of Montipora capitata tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

DirectionPartnersMost correlated partnerPCC
Positively correlated31g8232.t10.976572807831448
Negatively correlated7g16981.t1-0.928249639766799

Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Montipora capitata, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

AnalysisWhat it doesStatus
Primer designDesign PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.template foundopen →
BLASTSearch this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.template foundopen →
Expression heatmapDraw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.readyopen →
Gene family / orthogroupLook this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.open →
Gene set analysisStart a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.open →
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