Genomic Location: :...
NR annotation: XP_002162239.2, eukaryotic translation initiation factor 2 subunit 3, Y-linked [Hydra vulgaris]
| CDS | |||||
| Transcript |
| Protein |
| Uniprot term | Description | ||||
|---|---|---|---|---|---|
| C9WPN6 | Eukaryotic translation initiation factor 2 subunit 3, Y-linked OS=Rattus norvegicus OX=10116 GN=Eif2s3y PE=2 SV=2 | ||||
| P41091 | Eukaryotic translation initiation factor 2 subunit 3 OS=Homo sapiens OX=9606 GN=EIF2S3 PE=1 SV=3 | ||||
| Q9Z0N1 | Eukaryotic translation initiation factor 2 subunit 3, X-linked OS=Mus musculus OX=10090 GN=Eif2s3x PE=1 SV=2 |
| Gene family | Subfamily |
|---|---|
| Ubiquitin Family | UBD|ZnF|NZF |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF16172 | DOCK_N | DOCK N-terminus | Family | Interproscan |
| PF00641 | zf-RanBP | Zn-finger in Ran binding protein and others | Domain | Interproscan |
| PF00648 | Peptidase_C2 | Calpain family cysteine protease | Family | Interproscan |
| PF03144 | GTP_EFTU_D2 | Elongation factor Tu domain 2 | Domain | Interproscan |
| PF09173 | eIF2_C | Initiation factor eIF2 gamma, C terminal | Domain | Interproscan |
| PF00009 | GTP_EFTU | Elongation factor Tu GTP binding domain | Domain | Interproscan |
| PF03045 | DAN | DAN domain | Domain | Interproscan |
| PF02347 | GDC-P | Glycine cleavage system P-protein | Domain | Interproscan |
| PF15811 | SVIP | Small VCP/p97-interacting protein | Family | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR032376 | Domain | Dedicator of cytokinesis, N-terminal domain | Interproscan |
| IPR026791 | Family | Dedicator of cytokinesis | Interproscan |
| IPR042455 | Homologous_superfamily | Dedicator of cytokinesis, N-terminal, subdomain 1 | Interproscan |
| IPR001876 | Domain | Zinc finger, RanBP2-type | Interproscan |
| IPR050420 | Family | Calpain | Interproscan |
| IPR036443 | Homologous_superfamily | Zinc finger, RanBP2-type superfamily | Interproscan |
| IPR022684 | Family | Peptidase C2, calpain family | Interproscan |
| IPR038765 | Homologous_superfamily | Papain-like cysteine peptidase superfamily | Interproscan |
| IPR001300 | Domain | Peptidase C2, calpain, catalytic domain | Interproscan |
| IPR044128 | Domain | Initiation factor eIF2 gamma, GTP-binding domain | Interproscan |
| IPR027417 | Homologous_superfamily | P-loop containing nucleoside triphosphate hydrolase | Interproscan |
| IPR009000 | Homologous_superfamily | Translation protein, beta-barrel domain superfamily | Interproscan |
| IPR044127 | Domain | Initiation factor eIF2 gamma, domain 2 | Interproscan |
| IPR009001 | Homologous_superfamily | Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal | Interproscan |
| IPR050543 | Family | Eukaryotic Initiation Factor 2 Gamma Subunit | Interproscan |
| IPR000795 | Domain | Translational (tr)-type GTP-binding domain | Interproscan |
| IPR004161 | Domain | Translation elongation factor EFTu-like, domain 2 | Interproscan |
| IPR015256 | Domain | Initiation factor eIF2 gamma, C-terminal | Interproscan |
| IPR006207 | Domain | Cystine knot, C-terminal | Interproscan |
| IPR004133 | Domain | DAN | Interproscan |
| IPR029034 | Homologous_superfamily | Cystine-knot cytokine | Interproscan |
| IPR049315 | Domain | Glycine cleavage system P-protein, N-terminal domain | Interproscan |
| IPR015421 | Homologous_superfamily | Pyridoxal phosphate-dependent transferase, major domain | Interproscan |
| IPR020581 | Family | Glycine cleavage system P protein | Interproscan |
| IPR015424 | Homologous_superfamily | Pyridoxal phosphate-dependent transferase | Interproscan |
| IPR031632 | Family | Small VCP/p97-interacting protein | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR45653 | DEDICATOR OF CYTOKINESIS | Interproscan |
| PTHR10183 | CALPAIN | Interproscan |
| PTHR42854 | EUKARYOTIC TRANSLATION INITIATION FACTOR 2 SUBUNIT 3 FAMILY MEMBER | Interproscan |
| PTHR15283 | GREMLIN 1 | Interproscan |
| PTHR11773 | GLYCINE DEHYDROGENASE, DECARBOXYLATING | Interproscan |
| PTHR35269 | SMALL VCP/P97-INTERACTING PROTEIN | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0005085 | Molecular Function | guanyl-nucleotide exchange factor activity | Interproscan |
| GO:0005737 | Cellular Component | cytoplasm | Interproscan |
| GO:0005886 | Cellular Component | plasma membrane | Interproscan |
| GO:0007264 | Biological Process | small GTPase-mediated signal transduction | Interproscan |
| GO:0031267 | Molecular Function | small GTPase binding | Interproscan |
| GO:0004198 | Molecular Function | calcium-dependent cysteine-type endopeptidase activity | Interproscan |
| GO:0006508 | Biological Process | proteolysis | Interproscan |
| GO:0005525 | Molecular Function | GTP binding | Interproscan |
| GO:0000049 | Molecular Function | tRNA binding | Interproscan |
| GO:0001731 | Biological Process | formation of translation preinitiation complex | Interproscan |
| GO:0003743 | Molecular Function | translation initiation factor activity | Interproscan |
| GO:0005829 | Cellular Component | cytosol | Interproscan |
| GO:0005850 | Cellular Component | eukaryotic translation initiation factor 2 complex | Interproscan |
| GO:0003924 | Molecular Function | GTPase activity | Interproscan |
| GO:0005615 | Cellular Component | extracellular space | Interproscan |
| GO:0009887 | Biological Process | animal organ morphogenesis | Interproscan |
| GO:0036122 | Molecular Function | BMP binding | Interproscan |
| GO:0038098 | Biological Process | sequestering of BMP from receptor via BMP binding | Interproscan |
| GO:0048018 | Molecular Function | receptor ligand activity | Interproscan |
| GO:0004375 | Molecular Function | glycine dehydrogenase (decarboxylating) activity | Interproscan |
| GO:0005739 | Cellular Component | mitochondrion | Interproscan |
| GO:0005960 | Cellular Component | glycine cleavage complex | Interproscan |
| GO:0006546 | Biological Process | glycine catabolic process | Interproscan |
| GO:0016594 | Molecular Function | glycine binding | Interproscan |
| GO:0019464 | Biological Process | glycine decarboxylation via glycine cleavage system | Interproscan |
| GO:0030170 | Molecular Function | pyridoxal phosphate binding | Interproscan |
| GO:0005789 | Cellular Component | endoplasmic reticulum membrane | Interproscan |
| GO:0010508 | Biological Process | positive regulation of autophagy | Interproscan |
| GO:0031225 | Cellular Component | obsolete anchored component of membrane | Interproscan |
| GO:1903070 | Biological Process | obsolete negative regulation of ER-associated ubiquitin-dependent protein catabolic process | Interproscan |
| GO:1904153 | Biological Process | negative regulation of retrograde protein transport, ER to cytosol | Interproscan |
| GO:1904240 | Biological Process | negative regulation of VCP-NPL4-UFD1 AAA ATPase complex assembly | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K14014 | SVIP; small VCP/p97-interacting protein | - | Translation factors | ko03012 | deepkoala |
| Protein processing in endoplasmic reticulum | ko04141 | deepkoala |